Free for academic non-profit institutions. Other users need a Commercial license
PRSS53 (Serine Protease 53) is a Protein Coding gene. Diseases associated with PRSS53 include Episodic Kinesigenic Dyskinesia 1. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase activity. An important paralog of this gene is PRSS36.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0004252 | serine-type endopeptidase activity | IBA | 21873635 |
GO:0008233 | peptidase activity | IEA | -- |
GO:0008236 | serine-type peptidase activity | IEA | -- |
GO:0016787 | hydrolase activity | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005576 | extracellular region | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006508 | proteolysis | IEA | -- |
Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
---|---|---|---|---|---|---|
Warfarin | Approved | Pharma | 609 |
ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | |||||||||||||||||||||
SP2: | |||||||||||||||||||||
SP3: |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | PRSS53 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | PRSS53 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | PRSS53 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Prss53 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Prss53 30 |
|
||
Oppossum (Monodelphis domestica) |
Mammalia | PRSS53 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | PRSS53 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | PRSS53 31 |
|
OneToOne | |
Zebrafish (Danio rerio) |
Actinopterygii | BX571714.1 31 |
|
ManyToMany | |
zgc:92313 31 |
|
ManyToMany |
SNP ID | Clinical significance and condition | Chr 16 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs201075024 | Benign: Vitamin K-Dependent Clotting Factors | 31,087,679(-) | C/T | MISSENSE_VARIANT |
Disorder | Aliases | PubMed IDs |
---|---|---|
episodic kinesigenic dyskinesia 1 |
|
|