Aliases for PRSS47 Gene

Aliases for PRSS47 Gene

  • Serine Protease 47 2 3 5
  • Putative Serine Protease 47 3 4
  • Protease, Serine 47 2 3
  • EC 3.4.21.- 4
  • PRSS47 5

External Ids for PRSS47 Gene

Previous GeneCards Identifiers for PRSS47 Gene

  • GC09M094941
  • GC09U902017

Summaries for PRSS47 Gene

GeneCards Summary for PRSS47 Gene

PRSS47 (Serine Protease 47) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase activity.

Additional gene information for PRSS47 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for PRSS47 Gene

Genomics for PRSS47 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for PRSS47 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09J092189 Enhancer 0.7 Ensembl CraniofacialAtlas 600.7 +1.3 1296 1.9 GABPA NFIC BCOR GABPB1 RARA NFIA ETV4 ZNF48 ZMYM3 ELF1 PRSS47 CENPP OGN CARD19 lnc-CENPP-8 SPTLC1
GH09J092192 Enhancer 0.2 Ensembl 600.7 -0.9 -944 0.2 PRSS47 ENSG00000236115 IARS1
GH09J092145 Promoter/Enhancer 1.7 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.3 +43.8 43778 3.6 ARHGAP35 SP1 PRDM10 ZNF629 ZNF512 LEF1 IKZF1 ZNF692 TARDBP JUND lnc-SPTLC1-4 NOL8 MTND4P15 SPTLC1 IARS1 MTCO3P29 LINC00475 ENSG00000234537 LOC112268047 ENSG00000236717
GH09J092180 Enhancer 1 Ensembl ENCODE 0.4 +10.9 10855 4.2 IKZF1 JUND ZIC2 REST NR2C1 ZNF24 HDAC1 MGA CBX3 UBTF CENPP ENSG00000236115 SPTLC1 OGN CARD19 piR-54390-003 lnc-CENPP-8 PRSS47
GH09J092197 Enhancer 0.9 Ensembl ENCODE 0.4 -5.9 -5944 0.6 GATAD2A TFE3 RXRB CEBPA SOX13 CEBPB ZSCAN5C FOXA2 CREB1 TEAD1 ENSG00000236115 PRSS47 IARS1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around PRSS47 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for PRSS47

Genomic Locations for PRSS47 Gene

Genomic Locations for PRSS47 Gene
chr9:92,177,235-92,191,156
(GRCh38/hg38)
Size:
13,922 bases
Orientation:
Minus strand

Genomic View for PRSS47 Gene

Genes around PRSS47 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PRSS47 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PRSS47 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PRSS47 Gene

Proteins for PRSS47 Gene

  • Protein details for PRSS47 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MTI9-PRS47_HUMAN
    Recommended name:
    Putative serine protease 47
    Protein Accession:
    A8MTI9

    Protein attributes for PRSS47 Gene

    Size:
    375 amino acids
    Molecular mass:
    41188 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PRSS47 Gene

Post-translational modifications for PRSS47 Gene

  • Glycosylation at Asn183 and Asn203
  • Modification sites at PhosphoSitePlus

Other Protein References for PRSS47 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for PRSS47 Gene

Domains & Families for PRSS47 Gene

Gene Families for PRSS47 Gene

Protein Domains for PRSS47 Gene

Suggested Antigen Peptide Sequences for PRSS47 Gene

GenScript: Design optimal peptide antigens:
  • Putative serine protease 47 (PRS47_HUMAN)

Graphical View of Domain Structure for InterPro Entry

A8MTI9

UniProtKB/Swiss-Prot:

PRS47_HUMAN :
  • Belongs to the peptidase S1 family.
Family:
  • Belongs to the peptidase S1 family.
genes like me logo Genes that share domains with PRSS47: view

Function for PRSS47 Gene

Enzyme Numbers (IUBMB) for PRSS47 Gene

Phenotypes From GWAS Catalog for PRSS47 Gene

Gene Ontology (GO) - Molecular Function for PRSS47 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004252 serine-type endopeptidase activity IBA 21873635
genes like me logo Genes that share ontologies with PRSS47: view

Phenotypes for PRSS47 Gene

genes like me logo Genes that share phenotypes with PRSS47: view

Animal Model Products

  • Taconic Biosciences Mouse Models for PRSS47

No data available for Molecular function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PRSS47 Gene

Localization for PRSS47 Gene

Subcellular locations from UniProtKB/Swiss-Prot for PRSS47 Gene

Secreted.

Gene Ontology (GO) - Cellular Components for PRSS47 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IBA 21873635
genes like me logo Genes that share ontologies with PRSS47: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for PRSS47 Gene

Pathways & Interactions for PRSS47 Gene

PathCards logo

SuperPathways for PRSS47 Gene

No Data Available

Interacting Proteins for PRSS47 Gene

Gene Ontology (GO) - Biological Process for PRSS47 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006508 proteolysis IBA 21873635
genes like me logo Genes that share ontologies with PRSS47: view

No data available for Pathways by source and SIGNOR curated interactions for PRSS47 Gene

Drugs & Compounds for PRSS47 Gene

No Compound Related Data Available

Transcripts for PRSS47 Gene

mRNA/cDNA for PRSS47 Gene

1 REFSEQ mRNAs :
2 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for PRSS47 Gene

No ASD Table

Relevant External Links for PRSS47 Gene

GeneLoc Exon Structure for
PRSS47

Expression for PRSS47 Gene

Protein differential expression in normal tissues from HIPED for PRSS47 Gene

This gene is overexpressed in Breast (58.6) and Monocytes (10.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for PRSS47 Gene



Protein tissue co-expression partners for PRSS47 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for PRSS47

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for PRSS47 Gene

Orthologs for PRSS47 Gene

Evolution for PRSS47 Gene

ENSEMBL:
Gene Tree for PRSS47 (if available)
TreeFam:
Gene Tree for PRSS47 (if available)

No data available for Orthologs for PRSS47 Gene

Paralogs for PRSS47 Gene

genes like me logo Genes that share paralogs with PRSS47: view

No data available for Paralogs for PRSS47 Gene

Variants for PRSS47 Gene

Additional dbSNP identifiers (rs#s) for PRSS47 Gene

Additional Variant Information for PRSS47 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
PRSS47

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for PRSS47 Gene

Disorders for PRSS47 Gene

Additional Disease Information for PRSS47

No disorders were found for PRSS47 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PRSS47 Gene

Publications for PRSS47 Gene

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3
  2. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray SJ … Dunham I (Nature 2004) 4

Products for PRSS47 Gene

Sources for PRSS47 Gene