Aliases for PRSS40B Gene

Aliases for PRSS40B Gene

  • Serine Protease 40B (Pseudogene) 2 3 5
  • Serine Protease 40B 2
  • PRSS40B 5

External Ids for PRSS40B Gene

Previous GeneCards Identifiers for PRSS40B Gene

  • GC02M130537
  • GC02M130542
  • GC02M130606

Summaries for PRSS40B Gene

GeneCards Summary for PRSS40B Gene

PRSS40B (Serine Protease 40B (Pseudogene)) is a Pseudogene.

Additional gene information for PRSS40B Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for PRSS40B Gene

Genomics for PRSS40B Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for PRSS40B Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02J130719 Enhancer 0.4 Ensembl 6.6 -170.3 -170273 0.8 KLF1 EGR2 ZFHX2 EGR1 PRSS40B RF00994-515 GPR148 piR-43708-003 ENSG00000229797 POTEJ
GH02J130547 Promoter 0.3 EPDnew 0.7 +2.5 2466 0.1 piR-42839-001 HSALNG0018826 PRSS40B lnc-PRSS40B-1 HSALNG0018827-001 lnc-PRSS40B-2 CFC1B CFC1
GH02J130543 Enhancer 0.2 Ensembl 0.4 +5.5 5527 1.6 HSALNG0018827-001 piR-42839-001 HSALNG0018826 PRSS40B lnc-PRSS40B-1 CFC1B CFC1
GH02J130536 Enhancer 0.2 dbSUPER 0.4 +13.4 13354 0.9 piR-46320-001 ENSG00000225341 PRSS40B lnc-PRSS40B-1 HSALNG0018826 CFC1B CFC1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around PRSS40B on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for PRSS40B Gene

Latest Assembly
chr2:130,536,570-130,549,928
(GRCh38/hg38)
Size:
13,359 bases
Orientation:
Minus strand

Previous Assembly
chr2:131,294,143-131,307,488
(GRCh37/hg19 by Entrez Gene)
Size:
13,346 bases
Orientation:
Minus strand

chr2:131,296,668-131,307,456
(GRCh37/hg19 by Ensembl)
Size:
10,789 bases
Orientation:
Minus strand

Genomic View for PRSS40B Gene

Genes around PRSS40B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PRSS40B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PRSS40B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PRSS40B Gene

Proteins for PRSS40B Gene

Post-translational modifications for PRSS40B Gene

No Post-translational modifications

No data available for DME Specific Peptides for PRSS40B Gene

Domains & Families for PRSS40B Gene

Gene Families for PRSS40B Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
genes like me logo Genes that share domains with PRSS40B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for PRSS40B Gene

Function for PRSS40B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PRSS40B Gene

Localization for PRSS40B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for PRSS40B Gene

Pathways & Interactions for PRSS40B Gene

PathCards logo

SuperPathways for PRSS40B Gene

No Data Available

Gene Ontology (GO) - Biological Process for PRSS40B Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for PRSS40B Gene

Drugs & Compounds for PRSS40B Gene

No Compound Related Data Available

Transcripts for PRSS40B Gene

mRNA/cDNA for PRSS40B Gene

1 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for PRSS40B Gene

No ASD Table

Relevant External Links for PRSS40B Gene

GeneLoc Exon Structure for
PRSS40B

Expression for PRSS40B Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for PRSS40B

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for PRSS40B Gene

Orthologs for PRSS40B Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for PRSS40B Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia -- 30
  • 95 (a)
OneToOne
Species where no ortholog for PRSS40B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for PRSS40B Gene

ENSEMBL:
Gene Tree for PRSS40B (if available)
TreeFam:
Gene Tree for PRSS40B (if available)
Alliance of Genome Resources:
Additional Orthologs for PRSS40B

Paralogs for PRSS40B Gene

No data available for Paralogs for PRSS40B Gene

Variants for PRSS40B Gene

Structural Variations from Database of Genomic Variants (DGV) for PRSS40B Gene

Variant ID Type Subtype PubMed ID
dgv2032n106 OTHER inversion 24896259
dgv2035n106 CNV duplication 24896259
dgv4074n100 CNV gain 25217958
esv2759092 CNV gain+loss 17122850
esv3584076 CNV loss 25503493
esv3592455 CNV loss 21293372
nsv1005664 CNV loss 25217958
nsv1072452 CNV deletion 25765185
nsv1072453 CNV deletion 25765185
nsv1118879 CNV deletion 24896259
nsv1147463 OTHER inversion 26484159
nsv1148026 CNV duplication 26484159
nsv428403 CNV loss 18775914
nsv583134 CNV loss 21841781
nsv7327 OTHER inversion 18451855
nsv953164 CNV deletion 24416366
nsv961509 CNV duplication 23825009

Additional Variant Information for PRSS40B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
PRSS40B
Leiden Open Variation Database (LOVD)
PRSS40B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , dbSNP identifiers (rs#s) for variants without ClinVar clinical significance and Variation tolerance for PRSS40B Gene

Disorders for PRSS40B Gene

Additional Disease Information for PRSS40B

No disorders were found for PRSS40B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PRSS40B Gene

Publications for PRSS40B Gene

No publications were found for PRSS40B Gene.

No data available for Mastermind for PRSS40B Gene

Products for PRSS40B Gene

Sources for PRSS40B Gene