Aliases for PRSS16 Gene
External Ids for PRSS16 Gene
Previous GeneCards Identifiers for PRSS16 Gene
This gene encodes a serine protease expressed exclusively in the thymus. It is thought to play a role in the alternative antigen presenting pathway used by cortical thymic epithelial cells during the positive selection of T cells. The gene is found in the large histone gene cluster on chromosome 6, near the major histocompatibility complex (MHC) class I region. A second transcript variant has been described, but its full length nature has not been determined. [provided by RefSeq, Jul 2008]
GeneCards Summary for PRSS16 Gene
PRSS16 (Protease, Serine 16) is a Protein Coding gene. Diseases associated with PRSS16 include Diabetes Mellitus, Insulin-Dependent. Gene Ontology (GO) annotations related to this gene include serine-type peptidase activity. An important paralog of this gene is DPP7.
UniProtKB/Swiss-Prot for PRSS16 Gene
Protease that may play a role in T-cell development.