Aliases for PRR7 Gene
External Ids for PRR7 Gene
Previous GeneCards Identifiers for PRR7 Gene
GeneCards Summary for PRR7 Gene
PRR7 (Proline Rich 7, Synaptic) is a Protein Coding gene. An important paralog of this gene is WBP1.
UniProtKB/Swiss-Prot Summary for PRR7 Gene
Acts as a synapse-to-nucleus messenger to promote NMDA receptor-mediated excitotoxicity in neurons in a JUN-dependent manner (By similarity). Inhibits ubiquitination-mediated degradation and promotes phosphorylation and transcriptional activity of transcription factor JUN (PubMed:27458189). Might play a redundant role in the regulation of T cell receptor signaling (PubMed:21460222). Might promote apoptosis in T cells (PubMed:21460222).