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Aliases for PRR30 Gene
Aliases for PRR30 Gene
External Ids for PRR30 Gene
- HGNC: 28677
- Entrez Gene: 339779
- Ensembl: ENSG00000186143
- UniProtKB: Q53SZ7
Previous HGNC Symbols for PRR30 Gene
- C2orf53
Summaries for PRR30 Gene
GeneCards Summary for PRR30 Gene
PRR30 (Proline Rich 30) is a Protein Coding gene.
Additional gene information for PRR30 Gene
- HGNC(28677)
- Entrez Gene(339779)
- Ensembl(ENSG00000186143)
- UniProtKB(Q53SZ7)
- Open Targets Platform(ENSG00000186143)
- Search for PRR30 at DataMed
- Search for PRR30 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for PRR30 Gene
Genomics for PRR30 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for PRR30 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around PRR30 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for PRR30
Genomic Locations for PRR30 Gene
Genomic Locations for PRR30 Gene
- chr2:27,136,848-27,139,410
- (GRCh38/hg38)
- Size:
- 2,563 bases
- Orientation:
- Minus strand
- chr2:27,359,715-27,362,332
- (GRCh37/hg19)
- Size:
- 2,618 bases
- Orientation:
- Minus strand
Genomic View for PRR30 Gene
Genes around PRR30 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2p23.3 by HGNC
- 2p23.3 by Entrez Gene
- 2p23.3 by Ensembl
PRR30 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for PRR30 Gene
Proteins for PRR30 Gene
-
Protein details for PRR30 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q53SZ7-PRR30_HUMAN
- Recommended name:
- Proline-rich protein 30
- Protein Accession:
- Q53SZ7
- Q86UE2
Protein attributes for PRR30 Gene
- Size:
- 412 amino acids
- Molecular mass:
- 44690 Da
- Quaternary structure:
- No Data Available
Protein Expression for PRR30 Gene
Post-translational modifications for PRR30 Gene
Other Protein References for PRR30 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Creative Diagnostics Anti-C2ORF53 (aa 324-373) polyclonal antibody
-
Custom Antibody ServicesOriGene Antibodies for PRR30
- Novus Biologicals Antibodies for PRR30
- Invitrogen Antibodies for PRR30 (AFLGC-PRR30)
- antibodies-online: Show 20 available PRR30 Antibodies ranked by validation data
Protein Products
-
OriGene Purified Proteins for PRR30
- Search Origene for MassSpec and Protein Over-expression Lysates for PRR30
- Origene Custom Protein Services for PRR30
No data available for DME Specific Peptides for PRR30 Gene
Domains & Families for PRR30 Gene
Gene Families for PRR30 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for PRR30 Gene
Function for PRR30 Gene
Phenotypes From GWAS Catalog for PRR30 Gene
Phenotypes for PRR30 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for PRR30 - Select products 50% OFF >
- * PRR30 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for PRR30
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for PRR30
-
Santa Cruz Biotechnology (SCBT) CRISPR for PRR30
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PRR30
- Browse OriGene Inhibitory RNA Products For PRR30
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PRR30
Clone Products
- Applied Biological Materials (abm): Clones for PRR30 - Select products 50% OFF >
- * PRR30 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for PRR30
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PRR30
Cell Line Products
-
Horizon Cell Lines for PRR30
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PRR30 Gene
Localization for PRR30 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 2 |
| cytosol | 1 |
| peroxisome | 0 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for PRR30 Gene
Pathways & Interactions for PRR30 Gene
Interacting Proteins for PRR30 Gene
Selected Interacting proteins:
Q53SZ7-PRR30_HUMAN
ENSP00000335017
for PRR30 Gene via
UniProtKB
STRING
GPS-Prot Interaction Network for PRR30
No data available for Pathways by source and SIGNOR curated interactions for PRR30 Gene
Transcripts for PRR30 Gene
mRNA/cDNA for PRR30 Gene
- 1 REFSEQ mRNAs :
- 6 NCBI additional mRNA sequence :
- 2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000335524 2008 nts (view in UCSC)
- ENST00000432962 1440 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for PRR30 - Select products 50% OFF >
- * PRR30 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for PRR30
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for PRR30
-
Santa Cruz Biotechnology (SCBT) CRISPR for PRR30
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PRR30
- Browse OriGene Inhibitory RNA Products For PRR30
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PRR30
Clone Products
- Applied Biological Materials (abm): Clones for PRR30 - Select products 50% OFF >
- * PRR30 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for PRR30
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PRR30
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | · | 4c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||
| SP2: | - | - | |||||||||||||||||
| SP3: |
Relevant External Links for PRR30 Gene
- GeneLoc Exon Structure for
- PRR30
Expression for PRR30 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Testis (Reproductive System)
This gene is overexpressed in Testis (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for PRR30 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for PRR30
Primer Products
-
OriGene qPCR primer pairs for PRR30
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for PRR30 Gene
Orthologs for PRR30 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | C2AH2orf53 30 |
|
||
| C2orf53 31 |
|
OneToOne | |||
| Cow (Bos Taurus) |
Mammalia | C11H2orf53 30 |
|
||
| C2orf53 31 |
|
OneToOne | |||
| Rat (Rattus norvegicus) |
Mammalia | LOC100322897 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | 1700110M21Rik 30 31 |
|
OneToOne | |
| Prr30 17 |
|
||||
| Platypus (Ornithorhynchus anatinus) |
Mammalia | C2orf53 31 |
|
OneToOne |
- Species where no ortholog for PRR30 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- Dog (Canis familiaris)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Evolution for PRR30 Gene
- ENSEMBL:
- Gene Tree for PRR30 (if available)
- TreeFam:
- Gene Tree for PRR30 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for PRR30: view image
Paralogs for PRR30 Gene
No data available for Paralogs for PRR30 Gene
Variants for PRR30 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for PRR30 Gene
| SNP ID | Clinical significance and condition | Chr 02 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs17855664 | - | p.Arg194Gly | |||
| rs3739097 | - | p.Arg222Cys |
Residual Variation Intolerance Score:
83.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.45;
71.47% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for PRR30 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PRR30 Gene
Disorders for PRR30 Gene
Additional Disease Information for PRR30
No disorders were found for PRR30 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PRR30 Gene
Publications for PRR30 Gene
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3
- A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P … Vidal M (Genomics 2007) 3
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier LW … Wilson RK (Nature 2005) 4
ExternalLinks
Products for PRR30 Gene
- Custom Antibody ServicesOriGene Antibodies for PRR30
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for PRR30
- Search Origene for MassSpec and Protein Over-expression Lysates for PRR30
- Origene Custom Protein Services for PRR30
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PRR30
- Browse OriGene Inhibitory RNA Products For PRR30
- OriGene qPCR primer pairs for PRR30
- OriGene CRISPR knockouts for PRR30
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For PRR30
- Sino Biological Human cDNA Clone for PRR30
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for PRR30
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for PRR30 (AFLGC-PRR30)
- VectorBuilder Custom and pre-made DNA vectors for PRR30 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for PRR30 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for PRR30 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for PRR30 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for PRR30
- antibodies-online: Show 20 available PRR30 Antibodies ranked by validation data
- antibodies-online: Search results for available PRR30 related products ranked by validation data
- antibodies-online: Search results for available PRR30 related products ranked by validation data
- Horizon Cell Lines for PRR30
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for PRR30
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PRR30
- Search GeneCopoeia for miRNA 3'UTR Target clone products for PRR30
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PRR30
Sources for PRR30 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB