Aliases for PRR29 Gene

Aliases for PRR29 Gene

  • Proline Rich 29 2 3 5
  • Proline-Rich Protein 29 3 4
  • C17orf72 3 4
  • Chromosome 17 Open Reading Frame 72 2

External Ids for PRR29 Gene

Previous HGNC Symbols for PRR29 Gene

  • C17orf72

Summaries for PRR29 Gene

GeneCards Summary for PRR29 Gene

PRR29 (Proline Rich 29) is a Protein Coding gene.

Additional gene information for PRR29 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for PRR29 Gene

Genomics for PRR29 Gene

GeneHancer (GH) Regulatory Elements for PRR29 Gene

Promoters and enhancers for PRR29 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J063997 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 516.6 0.0 -18 2.6 HNRNPK ZBTB40 ZNF217 SIN3A NRF1 ZIC2 ZBTB26 SAP30 RFX1 U2AF2 PRR29 PRR29-AS1 SCN4A
GH17J064000 Promoter 0.7 Ensembl 500.7 +2.0 1957 0.2 TRIM24 CEBPG BCOR ZNF664 ATF4 CEBPB ATF3 ATF2 ATF7 SMARCA5 PRR29 PRR29-AS1 piR-45146 piR-53421
GH17J064013 Promoter/Enhancer 2.1 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 33.9 +21.7 21683 12.9 FOXK2 ZBTB40 ZNF217 CTCF USF1 SP1 BCLAF1 PHB2 TEAD4 ZNF639 ICAM2 lnc-ERN1-4 PRR29 CSHL1 GH1 SCN4A ACE MILR1 CEP95 LIMD2
GH17J064005 Promoter/Enhancer 1.8 EPDnew Ensembl ENCODE dbSUPER 37.9 +9.5 9455 5.1 NRF1 POLR2G NCOR1 ZBTB5 ZIC2 ZNF263 HES1 TOE1 MYC CTBP1 ICAM2 PRR29 CSHL1 GH1 RF00017-2500 lnc-ICAM2-2 lnc-ERN1-4
GH17J064001 Enhancer 0.7 ENCODE dbSUPER 40.8 +3.8 3780 1.3 CEBPB POLR2G GABPB1 ETV4 NFIL3 HLF POLR2A NR3C1 ETV5 RBFOX2 lnc-ICAM2-2 piR-45146 piR-53421 PRR29 PRR29-AS1 ICAM2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around PRR29 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for PRR29

Genomic Locations for PRR29 Gene

Genomic Locations for PRR29 Gene
chr17:63,998,344-64,004,305
(GRCh38/hg38)
Size:
5,962 bases
Orientation:
Plus strand
chr17:62,075,711-62,081,664
(GRCh37/hg19)
Size:
5,954 bases
Orientation:
Plus strand

Genomic View for PRR29 Gene

Genes around PRR29 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PRR29 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PRR29 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PRR29 Gene

Proteins for PRR29 Gene

  • Protein details for PRR29 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0C7W0-PRR29_HUMAN
    Recommended name:
    Proline-rich protein 29
    Protein Accession:
    P0C7W0
    Secondary Accessions:
    • B3KMP0
    • B4DZJ9
    • B4E2F8
    • E9PGL5
    • J3QKX4

    Protein attributes for PRR29 Gene

    Size:
    189 amino acids
    Molecular mass:
    20715 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for PRR29 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for PRR29 Gene

Post-translational modifications for PRR29 Gene

No Post-translational modifications

No data available for DME Specific Peptides for PRR29 Gene

Domains & Families for PRR29 Gene

Gene Families for PRR29 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for PRR29 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for PRR29 Gene

GenScript: Design optimal peptide antigens:
  • cDNA FLJ52641 (B4DG13_HUMAN)
genes like me logo Genes that share domains with PRR29: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for PRR29 Gene

Function for PRR29 Gene

Phenotypes for PRR29 Gene

genes like me logo Genes that share phenotypes with PRR29: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PRR29

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PRR29 Gene

Localization for PRR29 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for PRR29 gene
Compartment Confidence
plasma membrane 2
mitochondrion 1
peroxisome 1
nucleus 1
cytosol 1
extracellular 0

Subcellular locations from the

Human Protein Atlas (HPA)

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for PRR29 Gene

Pathways & Interactions for PRR29 Gene

PathCards logo

SuperPathways for PRR29 Gene

No Data Available

Interacting Proteins for PRR29 Gene

;

Gene Ontology (GO) - Biological Process for PRR29 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for PRR29 Gene

Drugs & Compounds for PRR29 Gene

No Compound Related Data Available

Transcripts for PRR29 Gene

mRNA/cDNA for PRR29 Gene

4 REFSEQ mRNAs :
9 NCBI additional mRNA sequence :
10 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PRR29

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for PRR29 Gene

No ASD Table

Relevant External Links for PRR29 Gene

GeneLoc Exon Structure for
PRR29

Expression for PRR29 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for PRR29 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for PRR29

genes like me logo Genes that share expression patterns with PRR29: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for PRR29 Gene

Orthologs for PRR29 Gene

This gene was present in the common ancestor of chordates.

Orthologs for PRR29 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C17H17orf72 30
  • 99.47 (n)
C17orf72 31
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C9H17orf72 30
  • 81.24 (n)
C17orf72 31
  • 60 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C19H17orf72 30
  • 75.69 (n)
mouse
(Mus musculus)
Mammalia 2310007L24Rik 31 30
  • 74.23 (n)
OneToOne
Prr29 17
rat
(Rattus norvegicus)
Mammalia RGD1307288 30
  • 72.79 (n)
oppossum
(Monodelphis domestica)
Mammalia C17orf72 31
  • 39 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C17orf72 31
  • 30 (a)
OneToOne
Species where no ortholog for PRR29 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for PRR29 Gene

ENSEMBL:
Gene Tree for PRR29 (if available)
TreeFam:
Gene Tree for PRR29 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for PRR29: view image

Paralogs for PRR29 Gene

No data available for Paralogs for PRR29 Gene

Variants for PRR29 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for PRR29 Gene

SNP ID Clinical significance and condition Chr 17 pos Variation AA Info Type
rs62070903 - p.Thr24Ser

Additional dbSNP identifiers (rs#s) for PRR29 Gene

Structural Variations from Database of Genomic Variants (DGV) for PRR29 Gene

Variant ID Type Subtype PubMed ID
nsv517272 CNV gain+loss 19592680
nsv833511 CNV loss 17160897
nsv952357 CNV deletion 24416366

Variation tolerance for PRR29 Gene

Gene Damage Index Score: 9.49; 88.76% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for PRR29 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
PRR29

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PRR29 Gene

Disorders for PRR29 Gene

Additional Disease Information for PRR29

No disorders were found for PRR29 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PRR29 Gene

Publications for PRR29 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 54
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 54
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 54
  4. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody MC … Nusbaum C (Nature 2006) 4 54

Products for PRR29 Gene

Sources for PRR29 Gene