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Aliases for PRR29 Gene

Aliases for PRR29 Gene

  • Proline Rich 29 2 3 5
  • C17orf72 3 4
  • Chromosome 17 Open Reading Frame 72 2
  • Proline-Rich Protein 29 3

External Ids for PRR29 Gene

Previous HGNC Symbols for PRR29 Gene

  • C17orf72

Summaries for PRR29 Gene

GeneCards Summary for PRR29 Gene

PRR29 (Proline Rich 29) is a Protein Coding gene.

Additional gene information for PRR29 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PRR29 Gene

Genomics for PRR29 Gene

GeneHancer (GH) Regulatory Elements for PRR29 Gene

Promoters and enhancers for PRR29 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J063997 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE dbSUPER 666.7 -0.4 -418 1.8 ARID4B SIN3A GLIS2 ELK1 ATF7 RUNX3 SP3 SP5 NCOA1 MXD4 PRR29 PRR29-AS1 FTSJ3 POLG2 SLC16A6P1 MAP3K3 SCN4A
GH17J064013 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 33.9 +21.7 21683 12.9 HDGF PKNOX1 FOXA2 SMAD1 MLX ARNT ARID4B SIN3A YBX1 DMAP1 ICAM2 CEP95 FTSJ3 POLG2 DDX42 DDX5 SLC16A6P1 SMARCD2 PRR29 ENSG00000265982
GH17J064005 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE dbSUPER 37.9 +9.5 9456 5.2 HDGF PKNOX1 FOXA2 NEUROD1 POLR2B ZNF766 ZNF263 SP5 ZNF592 SMARCA4 ICAM2 PRR29 CEP95 DDX42 DDX5 ENSG00000265982 CSHL1 GH1 KPNA2P3 POLG2
GH17J064001 Enhancer 1 Ensembl ENCODE dbSUPER 40.9 +3.8 3780 1.3 NFIL3 POLR2A HLF ETV4 CEBPA CEBPB CEBPG ETV5 GABPA GC17P064004 GC17M064000 PIR38145 PIR47420 PRR29 PRR29-AS1 ICAM2
GH17J064027 Enhancer 0.6 ENCODE 22.3 +29.2 29202 0.1 ZNF687 USF1 L3MBTL2 NFYC MAX USF2 NFYB CBFA2T2 FOSL2 MGA PRR29 CSHL1 GH1 GC17P064030 ICAM2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around PRR29 on UCSC Golden Path with GeneCards custom track

Genomic Locations for PRR29 Gene

Genomic Locations for PRR29 Gene
chr17:63,998,344-64,004,305
(GRCh38/hg38)
Size:
5,962 bases
Orientation:
Plus strand
chr17:62,075,711-62,081,664
(GRCh37/hg19)
Size:
5,954 bases
Orientation:
Plus strand

Genomic View for PRR29 Gene

Genes around PRR29 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PRR29 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PRR29 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PRR29 Gene

Proteins for PRR29 Gene

  • Protein details for PRR29 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0C7W0-PRR29_HUMAN
    Recommended name:
    Proline-rich protein 29
    Protein Accession:
    P0C7W0
    Secondary Accessions:
    • B3KMP0
    • B4DZJ9
    • B4E2F8
    • E9PGL5
    • J3QKX4

    Protein attributes for PRR29 Gene

    Size:
    189 amino acids
    Molecular mass:
    20715 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for PRR29 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for PRR29 Gene

Post-translational modifications for PRR29 Gene

No Post-translational modifications

No data available for DME Specific Peptides for PRR29 Gene

Domains & Families for PRR29 Gene

Gene Families for PRR29 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for PRR29 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for PRR29 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with PRR29: view

No data available for UniProtKB/Swiss-Prot for PRR29 Gene

Function for PRR29 Gene

Phenotypes for PRR29 Gene

genes like me logo Genes that share phenotypes with PRR29: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PRR29

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PRR29 Gene

Localization for PRR29 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for PRR29 gene
Compartment Confidence
plasma membrane 2
cytosol 2
extracellular 1
mitochondrion 1
peroxisome 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for PRR29 Gene

Pathways & Interactions for PRR29 Gene

SuperPathways for PRR29 Gene

No Data Available

Interacting Proteins for PRR29 Gene

Gene Ontology (GO) - Biological Process for PRR29 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for PRR29 Gene

Drugs & Compounds for PRR29 Gene

No Compound Related Data Available

Transcripts for PRR29 Gene

mRNA/cDNA for PRR29 Gene

(8) REFSEQ mRNAs :
(10) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PRR29

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for PRR29 Gene

No ASD Table

Relevant External Links for PRR29 Gene

GeneLoc Exon Structure for
PRR29
ECgene alternative splicing isoforms for
PRR29

Expression for PRR29 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for PRR29 Gene

NURSA nuclear receptor signaling pathways regulating expression of PRR29 Gene:

PRR29
genes like me logo Genes that share expression patterns with PRR29: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for PRR29 Gene

Orthologs for PRR29 Gene

This gene was present in the common ancestor of chordates.

Orthologs for PRR29 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C17H17orf72 33
  • 99.47 (n)
C17orf72 34
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C9H17orf72 33
  • 81.24 (n)
C17orf72 34
  • 60 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C19H17orf72 33
  • 75.69 (n)
mouse
(Mus musculus)
Mammalia 2310007L24Rik 34 33
  • 74.23 (n)
OneToOne
Prr29 16
rat
(Rattus norvegicus)
Mammalia RGD1307288 33
  • 72.79 (n)
oppossum
(Monodelphis domestica)
Mammalia C17orf72 34
  • 39 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C17orf72 34
  • 30 (a)
OneToOne
Species where no ortholog for PRR29 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for PRR29 Gene

ENSEMBL:
Gene Tree for PRR29 (if available)
TreeFam:
Gene Tree for PRR29 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for PRR29: view image

Paralogs for PRR29 Gene

No data available for Paralogs for PRR29 Gene

Variants for PRR29 Gene

Sequence variations from dbSNP and Humsavar for PRR29 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1000648479 -- 63,999,304(+) G/A intron_variant
rs1000751123 -- 63,999,666(+) A/T intron_variant
rs1000904637 -- 64,004,537(+) A/G downstream_transcript_variant
rs1000949632 -- 64,004,251(+) C/T 3_prime_UTR_variant, genic_downstream_transcript_variant
rs1001128721 -- 63,999,795(+) G/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for PRR29 Gene

Variant ID Type Subtype PubMed ID
nsv517272 CNV gain+loss 19592680
nsv833511 CNV loss 17160897
nsv952357 CNV deletion 24416366

Variation tolerance for PRR29 Gene

Gene Damage Index Score: 9.49; 88.76% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for PRR29 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
PRR29

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PRR29 Gene

Disorders for PRR29 Gene

Additional Disease Information for PRR29

No disorders were found for PRR29 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PRR29 Gene

Publications for PRR29 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58
  4. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody MC … Nusbaum C (Nature 2006) 4 58

Products for PRR29 Gene

Sources for PRR29 Gene

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