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The protein encoded by this gene tethers heterochromatin to the nuclear laminar scaffold by binding heterochromatin protein 1 (HP1) and the nuclear lamina. The tether is broken during mitosis and reforms quickly after mitosis, with the encoded protein first binding HP1 and then attaching to the nuclear lamina. This protein also has been shown to promote MyoD activity and skelet... See more...
Aliases for PRR14 Gene
External Ids for PRR14 Gene
- HGNC: 28458
- Entrez Gene: 78994
- Ensembl: ENSG00000156858
- OMIM: 617423
- UniProtKB: Q9BWN1
Previous GeneCards Identifiers for PRR14 Gene
- GC16P030570
- GC16P030662
- GC16P028225
Summaries for PRR14 Gene
-
The protein encoded by this gene tethers heterochromatin to the nuclear laminar scaffold by binding heterochromatin protein 1 (HP1) and the nuclear lamina. The tether is broken during mitosis and reforms quickly after mitosis, with the encoded protein first binding HP1 and then attaching to the nuclear lamina. This protein also has been shown to promote MyoD activity and skeletal myogenesis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2016]
GeneCards Summary for PRR14 Gene
PRR14 (Proline Rich 14) is a Protein Coding gene. An important paralog of this gene is PRR14L.
UniProtKB/Swiss-Prot Summary for PRR14 Gene
-
Functions in tethering peripheral heterochromatin to the nuclear lamina during interphase, possibly through the interaction with heterochromatin protein CBX5/HP1 alpha (PubMed:24209742). Might play a role in reattaching heterochromatin to the nuclear lamina at mitotic exit (PubMed:24209742). Promotes myoblast differentiation during skeletal myogenesis, possibly by stimulating transcription factor MyoD activity via binding to CBX5/HP1 alpha (PubMed:25906157). Involved in the positive regulation of the PI3K-Akt-mTOR signaling pathway and in promoting cell proliferation, possibly via binding to GRB2 (PubMed:27041574).
Additional gene information for PRR14 Gene
- HGNC(28458)
- Entrez Gene(78994)
- Ensembl(ENSG00000156858)
- OMIM(617423)
- UniProtKB(Q9BWN1)
- Open Targets Platform(ENSG00000156858)
- Search for PRR14 at DataMed
- Search for PRR14 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for PRR14 Gene
Genomics for PRR14 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for PRR14 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around PRR14 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for PRR14
- Top Transcription factor binding sites by QIAGEN in the PRR14 gene promoter:
-
- c-Myb
- CUTL1
- E2F
- E2F-1
- E2F-2
- E2F-3a
- E2F-4
- E2F-5
- Pax-4a
- Pax-5
Genomic Locations for PRR14 Gene
Genomic Locations for PRR14 Gene
- chr16:30,650,717-30,656,440
- (GRCh38/hg38)
- Size:
- 5,724 bases
- Orientation:
- Plus strand
- chr16:30,662,038-30,667,761
- (GRCh37/hg19)
- Size:
- 5,724 bases
- Orientation:
- Plus strand
Genomic View for PRR14 Gene
Genes around PRR14 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 16p11.2 by HGNC
- 16p11.2 by Entrez Gene
- 16p11.2 by Ensembl
PRR14 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for PRR14 Gene
Proteins for PRR14 Gene
-
Protein details for PRR14 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9BWN1-PRR14_HUMAN
- Recommended name:
- Proline-rich protein 14
- Protein Accession:
- Q9BWN1
- Q8WTX2
Protein attributes for PRR14 Gene
- Size:
- 585 amino acids
- Molecular mass:
- 64328 Da
- Quaternary structure:
-
- Interacts (via proline-rich region) with GRB2 (via SH3 domain 2) (PubMed:27041574). Interacts (via N-terminus) with CBX5 (PubMed:25906157).
Protein Expression for PRR14 Gene
Post-translational modifications for PRR14 Gene
Other Protein References for PRR14 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for PRR14
- Invitrogen Antibodies for PRR14 (AFLGC-PRR14)
- antibodies-online: Show 8 available PRR14 Antibodies ranked by validation data
Protein Products
-
OriGene Purified Proteins for PRR14
- Search Origene for MassSpec and Protein Over-expression Lysates for PRR14
- Origene Custom Protein Services for PRR14
No data available for DME Specific Peptides for PRR14 Gene
Domains & Families for PRR14 Gene
Gene Families for PRR14 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for PRR14 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for PRR14 Gene
- GenScript: Design optimal peptide antigens:
-
- Proline-rich protein 14 (PRR14_HUMAN)
- PRR14 protein (Q96D88_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for PRR14 Gene
Function for PRR14 Gene
Molecular function for PRR14 Gene
- UniProtKB/Swiss-Prot Function:
- Functions in tethering peripheral heterochromatin to the nuclear lamina during interphase, possibly through the interaction with heterochromatin protein CBX5/HP1 alpha (PubMed:24209742). Might play a role in reattaching heterochromatin to the nuclear lamina at mitotic exit (PubMed:24209742). Promotes myoblast differentiation during skeletal myogenesis, possibly by stimulating transcription factor MyoD activity via binding to CBX5/HP1 alpha (PubMed:25906157). Involved in the positive regulation of the PI3K-Akt-mTOR signaling pathway and in promoting cell proliferation, possibly via binding to GRB2 (PubMed:27041574).
Phenotypes From GWAS Catalog for PRR14 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 16189514 |
Phenotypes for PRR14 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for PRR14 - Select products 50% OFF >
- * PRR14 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for PRR14
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for PRR14
-
Santa Cruz Biotechnology (SCBT) CRISPR for PRR14
miRNA for PRR14 Gene
- miRTarBase miRNAs that target PRR14
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PRR14
- Browse OriGene Inhibitory RNA Products For PRR14
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PRR14
Clone Products
- Applied Biological Materials (abm): Clones for PRR14 - Select products 50% OFF >
- * PRR14 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for PRR14
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PRR14
Cell Line Products
-
Horizon Cell Lines for PRR14
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for PRR14 Gene
Localization for PRR14 Gene
Subcellular locations from UniProtKB/Swiss-Prot for PRR14 Gene
- Chromosome. Nucleus. Nucleus lamina. Nucleus, nucleoplasm. Note=During interphase, associated with peripheral heterochromatin at the nuclear lamina. Released from the nuclear lamina in mitotic prophase and remains highly dispersed in metaphase. Associates with chromatin at the onset of anaphase and relocalizes to the nuclear lamina in telophase. {ECO:0000269 PubMed:24209742}.
| Compartment | Confidence |
|---|---|
| nucleus | 4 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| cytosol | 1 |
| plasma membrane | 0 |
| extracellular | 0 |
| peroxisome | 0 |
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005652 | nuclear lamina | IEA | -- |
| GO:0005654 | nucleoplasm | IEA | -- |
| GO:0005694 | chromosome | IEA | -- |
Pathways & Interactions for PRR14 Gene
Interacting Proteins for PRR14 Gene
Selected Interacting proteins:
Q9BWN1-PRR14_HUMAN
ENSP00000441641
for PRR14 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for PRR14
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007517 | muscle organ development | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for PRR14 Gene
Transcripts for PRR14 Gene
mRNA/cDNA for PRR14 Gene
- 2 REFSEQ mRNAs :
- 11 NCBI additional mRNA sequence :
- 13 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000287463 2124 nts (view in UCSC)
- ENST00000300835 2198 nts (view in UCSC)
- ENST00000542965 2316 nts (view in UCSC)
- ENST00000563211 786 nts (view in UCSC)
- ENST00000563399 554 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for PRR14 - Select products 50% OFF >
- * PRR14 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for PRR14
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for PRR14
-
Santa Cruz Biotechnology (SCBT) CRISPR for PRR14
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PRR14
- Browse OriGene Inhibitory RNA Products For PRR14
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PRR14
Clone Products
- Applied Biological Materials (abm): Clones for PRR14 - Select products 50% OFF >
- * PRR14 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for PRR14
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PRR14
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | · | 3c | · | 3d | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12a | · | 12b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||||||||||||||||||||
| SP6: | - | ||||||||||||||||||||||||||||||||||||||||
| SP7: | |||||||||||||||||||||||||||||||||||||||||
| SP8: |
Relevant External Links for PRR14 Gene
- GeneLoc Exon Structure for
- PRR14
Expression for PRR14 Gene
This gene is overexpressed in Monocytes (29.3), Lung (24.3), and Bone marrow mesenchymal stem cell (7.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for PRR14 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for PRR14
SOURCE GeneReport for Unigene cluster for PRR14 Gene:
Hs.293629Evidence on tissue expression from TISSUES for PRR14 Gene
- Eye(4.3)
- Pancreas(4.2)
- Liver(4.1)
- Nervous system(3.9)
- Skin(2.9)
Primer Products
-
OriGene qPCR primer pairs for PRR14
-
OriGene qPCR primer pairs and template standards for PRR14
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for PRR14 Gene
Orthologs for PRR14 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | PRR14 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | PRR14 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | PRR14 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Prr14 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Prr14 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | PRR14 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | PRR14 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | PRR14 31 |
|
OneToOne | |
| Zebrafish (Danio rerio) |
Actinopterygii | prr14 31 |
|
OneToOne | |
| wufi75a02 30 |
|
||||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.2700 31 |
|
OneToMany |
- Species where no ortholog for PRR14 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for PRR14 Gene
- ENSEMBL:
- Gene Tree for PRR14 (if available)
- TreeFam:
- Gene Tree for PRR14 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for PRR14: view image
Paralogs for PRR14 Gene
Variants for PRR14 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for PRR14 Gene
| SNP ID | Clinical significance and condition | Chr 16 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs3747481 | - | p.Pro359Leu |
Residual Variation Intolerance Score:
14.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
11.63;
93.13% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for PRR14 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PRR14 Gene
Disorders for PRR14 Gene
Additional Disease Information for PRR14
No disorders were found for PRR14 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PRR14 Gene
Publications for PRR14 Gene
- The human protein PRR14 tethers heterochromatin to the nuclear lamina during interphase and mitotic exit. (PMID: 24209742) Poleshko A … Katz RA (Cell reports 2013) 2 3 4
- PRR14 is a novel activator of the PI3K pathway promoting lung carcinogenesis. (PMID: 27041574) Yang M … Yuan ZM (Oncogene 2016) 3 4
- A novel role of PRR14 in the regulation of skeletal myogenesis. (PMID: 25906157) Yang M … Yuan ZM (Cell death & disease 2015) 3 4
- A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
- Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations. (PMID: 31515488) Fragoza R … Yu H (Nature communications 2019) 3
ExternalLinks
Products for PRR14 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for PRR14
- Search Origene for MassSpec and Protein Over-expression Lysates for PRR14
- Origene Custom Protein Services for PRR14
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PRR14
- Browse OriGene Inhibitory RNA Products For PRR14
- OriGene qPCR primer pairs for PRR14
- OriGene qPCR primer pairs and template standards for PRR14
- OriGene CRISPR knockouts for PRR14
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For PRR14
- Sino Biological Human cDNA Clone for PRR14
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for PRR14
- Novus Biologicals proteins and lysates for PRR14
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for PRR14 (AFLGC-PRR14)
- VectorBuilder Custom and pre-made DNA vectors for PRR14 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for PRR14 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for PRR14 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for PRR14 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for PRR14
- antibodies-online: Show 8 available PRR14 Antibodies ranked by validation data
- antibodies-online: Search results for available PRR14 related products ranked by validation data
- antibodies-online: Search results for available PRR14 related products ranked by validation data
- Horizon Cell Lines for PRR14
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for PRR14
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PRR14
- Search GeneCopoeia for miRNA 3'UTR Target clone products for PRR14
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PRR14
Sources for PRR14 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
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- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
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- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB