Aliases for PRPS2 Gene
External Ids for PRPS2 Gene
Previous GeneCards Identifiers for PRPS2 Gene
This gene encodes a phosphoribosyl pyrophosphate synthetase that plays a central role in the synthesis of purines and pyrimidines. The encoded protein catalyzes the synthesis of 5-phosphoribosyl 1-pyrophosphate from ATP and D-ribose 5-phosphate. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
GeneCards Summary for PRPS2 Gene
PRPS2 (Phosphoribosyl Pyrophosphate Synthetase 2) is a Protein Coding gene. Among its related pathways are Pyrimidine metabolism (KEGG) and Metabolism. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and carbohydrate binding. An important paralog of this gene is PRPS1.
UniProtKB/Swiss-Prot for PRPS2 Gene
Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.