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PRPF38B (Pre-MRNA Processing Factor 38B) is a Protein Coding gene. Diseases associated with PRPF38B include Ulceroglandular Tularemia. Among its related pathways are mRNA Splicing - Major Pathway.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003723 | RNA binding | HDA | 22658674 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IEA | -- |
GO:0005681 | spliceosomal complex | IEA | -- |
GO:0071011 | precatalytic spliceosome | IEA,IBA | 21873635 |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | mRNA Splicing - Major Pathway |
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|
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000398 | mRNA splicing, via spliceosome | IEA | -- |
GO:0006397 | mRNA processing | IEA | -- |
GO:0008380 | RNA splicing | IEA | -- |
ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | · | 8c | ^ | 9a | · | 9b |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | |||||||||||||||||||||||||||||
SP2: | - | - | - | - | - | - | - | ||||||||||||||||||||||||
SP3: | - | - | - | - | - | ||||||||||||||||||||||||||
SP4: | - | - | - | - | |||||||||||||||||||||||||||
SP5: | - | - | |||||||||||||||||||||||||||||
SP6: | |||||||||||||||||||||||||||||||
SP7: | - | ||||||||||||||||||||||||||||||
SP8: |
This gene was present in the common ancestor of eukaryotes.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | PRPF38B 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | PRPF38B 30 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | PRPF38B 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | PRPF38B 30 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | PRPF38B 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Prpf38b 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Prpf38b 30 17 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | PRPF38B 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | PRPF38B 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | prpf38b 30 |
|
||
Str.11052 30 |
|
||||
African clawed frog (Xenopus laevis) |
Amphibia | Xl.8346 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | prpf38b 30 31 |
|
OneToOne | |
wufc43b05 30 |
|
||||
Fruit Fly (Drosophila melanogaster) |
Insecta | CG1622 31 |
|
OneToOne | |
Worm (Caenorhabditis elegans) |
Secernentea | Y108G3AL.2 31 |
|
OneToOne | |
Rice (Oryza sativa) |
Liliopsida | Os.10119 30 |
|
||
Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.10416 31 |
|
OneToOne | |
Sea Vase (Ciona intestinalis) |
Ascidiacea | Cin.9541 30 |
|
SNP ID | Clinical significance and condition | Chr 01 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs111751551 | Benign: not provided | 108,699,434(+) |
G/A NM_018061.4(PRPF38B):c.1055G>A (p.Arg352Lys) |
MISSENSE | |
rs386352353 | Uncertain Significance: not provided | 108,699,842(+) |
G/A NM_018061.4(PRPF38B):c.1463G>A (p.Arg488Gln) |
MISSENSE | |
rs761679182 | Uncertain Significance: Severe Myopia | 108,699,701(+) |
G/A NM_018061.4(PRPF38B):c.1322G>A (p.Ser441Asn) |
MISSENSE |
Disorder | Aliases | PubMed IDs |
---|---|---|
ulceroglandular tularemia |
|
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