Aliases for PRPF18 Gene
External Ids for PRPF18 Gene
Previous GeneCards Identifiers for PRPF18 Gene
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to the yeast splicing factor Prp18. [provided by RefSeq, Jul 2008]
GeneCards Summary for PRPF18 Gene
PRPF18 (Pre-MRNA Processing Factor 18) is a Protein Coding gene. Among its related pathways are mRNA Splicing - Major Pathway. Gene Ontology (GO) annotations related to this gene include potassium channel inhibitor activity. An important paralog of this gene is ENSG00000282246.
UniProtKB/Swiss-Prot Summary for PRPF18 Gene
Participates in the second step of pre-mRNA splicing.