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Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to the yeast splicing factor Prp18. [provided by... See more...
Aliases for PRPF18 Gene
Aliases for PRPF18 Gene
External Ids for PRPF18 Gene
- HGNC: 17351
- Entrez Gene: 8559
- Ensembl: ENSG00000165630
- OMIM: 604993
- UniProtKB: Q99633
Previous GeneCards Identifiers for PRPF18 Gene
- GC10P013611
- GC10P013779
- GC10P013633
- GC10P013669
- GC10P013540
- GC10P013628
Summaries for PRPF18 Gene
-
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to the yeast splicing factor Prp18. [provided by RefSeq, Jul 2008]
GeneCards Summary for PRPF18 Gene
PRPF18 (Pre-MRNA Processing Factor 18) is a Protein Coding gene. Among its related pathways are mRNA Splicing - Major Pathway. Gene Ontology (GO) annotations related to this gene include potassium channel inhibitor activity. An important paralog of this gene is ENSG00000282246.
UniProtKB/Swiss-Prot Summary for PRPF18 Gene
-
Participates in the second step of pre-mRNA splicing.
Additional gene information for PRPF18 Gene
- HGNC(17351)
- Entrez Gene(8559)
- Ensembl(ENSG00000165630)
- OMIM(604993)
- UniProtKB(Q99633)
- Open Targets Platform(ENSG00000165630)
- Monarch Initiative
- Search for PRPF18 at DataMed
- Search for PRPF18 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for PRPF18 Gene
Genomics for PRPF18 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for PRPF18 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around PRPF18 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for PRPF18
- Top Transcription factor binding sites by QIAGEN in the PRPF18 gene promoter:
-
- Bach1
- E47
- GCNF
- Lhx3a
- LHX3b
- POU2F1
- POU2F1a
- SREBP-1a
- SREBP-1b
- SREBP-1c
Genomic Locations for PRPF18 Gene
Genomic Locations for PRPF18 Gene
- chr10:13,586,811-13,645,344
- (GRCh38/hg38)
- Size:
- 58,534 bases
- Orientation:
- Plus strand
- chr10:13,628,927-13,672,868
- (GRCh37/hg19)
- Size:
- 43,942 bases
- Orientation:
- Plus strand
Genomic View for PRPF18 Gene
Genes around PRPF18 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 10p13 by HGNC
- 10p13 by Entrez Gene
- 10p13 by Ensembl
PRPF18 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for PRPF18 Gene
Proteins for PRPF18 Gene
-
Protein details for PRPF18 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q99633-PRP18_HUMAN
- Recommended name:
- Pre-mRNA-splicing factor 18
- Protein Accession:
- Q99633
- Q5T9P9
- Q9BUI9
Protein attributes for PRPF18 Gene
- Size:
- 342 amino acids
- Molecular mass:
- 39860 Da
- Quaternary structure:
-
- Heterodimer with PPIH. Interacts with PRPF4 and with the spliceosome. Part of a complex containing U4/U6 snRNPs.
Protein Expression for PRPF18 Gene
Post-translational modifications for PRPF18 Gene
Other Protein References for PRPF18 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- G Biosciences Immunotag™ PRPF18 Antibody
- Novus Biologicals Antibodies for PRPF18
-
Abcam antibodies for PRPF18
- Invitrogen Antibodies for PRPF18 (AFLGC-PRPF18)
-
Santa Cruz Biotechnology (SCBT) Antibodies for PRPF18
- Sino Biological Antibodies for PRPF18
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for PRPF18
- Origene Custom Protein Services for PRPF18
-
Abcam proteins for PRPF18
No data available for DME Specific Peptides for PRPF18 Gene
Domains & Families for PRPF18 Gene
Gene Families for PRPF18 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for PRPF18 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for PRPF18 Gene
- GenScript: Design optimal peptide antigens:
-
- PRP18 homolog (PRP18_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q99633- Family:
-
- Belongs to the PRP18 family.
Function for PRPF18 Gene
Molecular function for PRPF18 Gene
- UniProtKB/Swiss-Prot Function:
- Participates in the second step of pre-mRNA splicing.
Phenotypes From GWAS Catalog for PRPF18 Gene
Phenotypes for PRPF18 Gene
- MGI mutant phenotypes for PRPF18:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for PRPF18:
-
- Decreased hepcidin::fluc mRNA expression
- no effect
- Decreased vaccinia virus (VACV) infection
- Decreased viability
- shRNA abundance <= 25%
- Decreased G3BP1 protein expression and assembly in stress granules after arsenite stimulation
- Increased shRNA abundance (Z-score > 2)
- Decreased shRNA abundance (Z-score < -2)
- Decreased homologous recombination repair frequency
- Decreased viability in ovarian lineage
- Synthetic lethal with vaccinia virus (VACV) infection
Animal Models for PRPF18 Gene
- MGI Knock Outs for PRPF18:
-
- Prpf18 Prpf18<tm1.1(KOMP)Vlcg>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for PRPF18 - Select products 50% OFF >
- * PRPF18 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for PRPF18
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for PRPF18
-
Santa Cruz Biotechnology (SCBT) CRISPR for PRPF18
miRNA for PRPF18 Gene
- miRTarBase miRNAs that target PRPF18
-
- mmu-miR-541-5p (MIRT008207)
- mmu-miR-425-5p (MIRT008658)
- mmu-miR-5098 (MIRT586264)
- mmu-miR-466c-3p (MIRT586265)
- mmu-miR-466p-3p (MIRT586266)
- mmu-miR-466b-3p (MIRT586267)
- mmu-miR-466o-3p (MIRT586268)
- mmu-miR-466m-3p (MIRT586269)
- mmu-miR-1b-5p (MIRT586270)
- mmu-miR-717 (MIRT600504)
- mmu-miR-329-3p (MIRT600505)
- mmu-miR-362-3p (MIRT600506)
- mmu-miR-466g (MIRT600507)
- mmu-miR-3097-3p (MIRT603561)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PRPF18
- Browse OriGene Inhibitory RNA Products For PRPF18
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PRPF18
Clone Products
- Applied Biological Materials (abm): Clones for PRPF18 - Select products 50% OFF >
- * PRPF18 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for PRPF18
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PRPF18
No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for PRPF18 Gene
Localization for PRPF18 Gene
Subcellular locations from UniProtKB/Swiss-Prot for PRPF18 Gene
- Nucleus speckle. Note=Colocalizes with spliceosomal snRNPs. {ECO:0000250}.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 2 |
| peroxisome | 1 |
- Cytosol (2)
- Nuclear speckles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | TAS | 9000057 |
| GO:0005681 | spliceosomal complex | IEA,TAS | 9000057 |
| GO:0005682 | U5 snRNP | IBA | 21873635 |
| GO:0016607 | nuclear speck | IEA | -- |
| GO:0046540 | U4/U6 x U5 tri-snRNP complex | IBA | 21873635 |
Pathways & Interactions for PRPF18 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | mRNA Splicing - Major Pathway |
.47
|
.41
|
Pathways by source for PRPF18 Gene
1 BioSystems pathway for PRPF18 Gene
1 KEGG pathway for PRPF18 Gene
Interacting Proteins for PRPF18 Gene
Selected Interacting proteins:
Q99633-PRP18_HUMAN
ENSP00000367835
for PRPF18 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for PRPF18
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000350 | generation of catalytic spliceosome for second transesterification step | IBA | 21873635 |
| GO:0006397 | mRNA processing | TAS | 9000057 |
| GO:0008380 | RNA splicing | IEA,TAS | 9000057 |
| GO:0071048 | nuclear retention of unspliced pre-mRNA at the site of transcription | IBA | 21873635 |
No data available for SIGNOR curated interactions for PRPF18 Gene
Transcripts for PRPF18 Gene
mRNA/cDNA for PRPF18 Gene
- 1 REFSEQ mRNAs :
- 8 NCBI additional mRNA sequence :
- 3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000320054 788 nts (view in UCSC)
- ENST00000378572 1670 nts (view in UCSC)
- ENST00000417658 1062 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for PRPF18 - Select products 50% OFF >
- * PRPF18 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for PRPF18
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for PRPF18
-
Santa Cruz Biotechnology (SCBT) CRISPR for PRPF18
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PRPF18
- Browse OriGene Inhibitory RNA Products For PRPF18
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PRPF18
Clone Products
- Applied Biological Materials (abm): Clones for PRPF18 - Select products 50% OFF >
- * PRPF18 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for PRPF18
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PRPF18
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||||||||
| SP3: |
Relevant External Links for PRPF18 Gene
- GeneLoc Exon Structure for
- PRPF18
Expression for PRPF18 Gene
This gene is overexpressed in Breast (40.4), Prostate (8.7), and Ovary (6.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for PRPF18 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for PRPF18
SOURCE GeneReport for Unigene cluster for PRPF18 Gene:
Hs.729158Evidence on tissue expression from TISSUES for PRPF18 Gene
- Nervous system(4.5)
- Kidney(2.1)
Primer Products
-
OriGene qPCR primer pairs for PRPF18
-
OriGene qPCR primer pairs and template standards for PRPF18
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for PRPF18 Gene
Orthologs for PRPF18 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | PRPF18 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | PRPF18 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | PRPF18 30 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
| Mouse (Mus musculus) |
Mammalia | Prpf18 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Prpf18 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
ManyToMany | |
| -- 31 |
|
ManyToMany | |||
| -- 31 |
|
ManyToMany | |||
| Chicken (Gallus gallus) |
Aves | -- 31 |
|
OneToMany | |
| PRPF18 30 |
|
||||
| Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
OneToMany | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | prpf18 30 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.13654 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | prpf18 30 31 |
|
OneToMany | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP002307 30 |
|
||
| Fruit Fly (Drosophila melanogaster) |
Insecta | Prp18 30 31 32 |
|
OneToMany | |
| Worm (Caenorhabditis elegans) |
Secernentea | F32B6.3 30 31 32 |
|
OneToMany | |
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | PRP18 31 |
|
OneToMany | |
| Thale Cress (Arabidopsis thaliana) |
eudicotyledons | AT1G03140 30 |
|
||
| Rice (Oryza sativa) |
Liliopsida | Os07g0571900 30 |
|
||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.9226 31 |
|
OneToMany | |
| Sea Vase (Ciona intestinalis) |
Ascidiacea | Cin.1876 30 |
|
- Species where no ortholog for PRPF18 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for PRPF18 Gene
- ENSEMBL:
- Gene Tree for PRPF18 (if available)
- TreeFam:
- Gene Tree for PRPF18 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for PRPF18: view image
Paralogs for PRPF18 Gene
Paralogs for PRPF18 Gene
(1) SIMAP similar genes for PRPF18 Gene using alignment to 4 proteins:
- PRP18_HUMAN
- L8E7W4_HUMAN
- Q5T9P7_HUMAN
- Q5T9P8_HUMAN
Variants for PRPF18 Gene
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2761575 | CNV | gain | 21179565 |
| esv3891761 | CNV | gain | 25118596 |
| nsv831789 | CNV | gain+loss | 17160897 |
| nsv831790 | CNV | loss | 17160897 |
| nsv947743 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
26.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.54;
29.81% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for PRPF18 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- PRPF18
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for PRPF18 Gene
Disorders for PRPF18 Gene
Additional Disease Information for PRPF18
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No disorders were found for PRPF18 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PRPF18 Gene
Publications for PRPF18 Gene
- A human protein required for the second step of pre-mRNA splicing is functionally related to a yeast splicing factor. (PMID: 9000057) Horowitz DS … Krainer AR (Genes & development 1997) 2 3 4 23
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41
- A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PMID: 16385451) Grupe A … Goate A (American journal of human genetics 2006) 3 41
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- A cyclophilin functions in pre-mRNA splicing. (PMID: 11823439) Horowitz DS … Misteli T (The EMBO journal 2002) 3 4
ExternalLinks
Products for PRPF18 Gene
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for PRPF18
- Origene Custom Protein Services for PRPF18
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PRPF18
- Browse OriGene Inhibitory RNA Products For PRPF18
- OriGene qPCR primer pairs for PRPF18
- OriGene qPCR primer pairs and template standards for PRPF18
- OriGene CRISPR knockouts for PRPF18
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For PRPF18
- Sino Biological Human cDNA Clone for PRPF18
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for PRPF18
- Browse Sino Biological Assays
- Browse Antibodies
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for PRPF18
- Novus Biologicals proteins and lysates for PRPF18
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for PRPF18
- Abcam proteins for PRPF18
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for PRPF18 (AFLGC-PRPF18)
- VectorBuilder Custom and pre-made DNA vectors for PRPF18 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for PRPF18 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for PRPF18 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for PRPF18 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for PRPF18
- antibodies-online: Show 8 available PRPF18 Antibodies ranked by validation data
- Compare Top PRPF18 Antibodies
- antibodies-online: Search results for available PRPF18 related products ranked by validation data
- antibodies-online: Show 11 available PRPF18 Proteins ranked by validation data
- Compare Top PRPF18 Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for PRPF18
- Search Santa Cruz Biotechnology (SCBT) for PRPF18 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for PRPF18
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for PRPF18
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PRPF18
- Search GeneCopoeia for miRNA 3'UTR Target clone products for PRPF18
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PRPF18
Sources for PRPF18 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB