Free for academic non-profit institutions. Other users need a Commercial license

Aliases for PRMT8 Gene

Aliases for PRMT8 Gene

  • Protein Arginine Methyltransferase 8 2 3 5
  • Heterogeneous Nuclear Ribonucleoprotein Methyltransferase-Like Protein 4 3 4
  • Protein Arginine N-Methyltransferase 8 3 4
  • HRMT1L3 3 4
  • HRMT1L4 3 4
  • HMT1 HnRNP Methyltransferase-Like 3 (S. Cerevisiae) 2
  • HMT1 HnRNP Methyltransferase-Like 4 (S. Cerevisiae) 2
  • Protein Arginine N-Methyltransferase 4 3
  • HMT1 HnRNP Methyltransferase-Like 3 3
  • Arginine Methyltransferase 8 3
  • EC 2.1.1.319 4
  • EC 2.1.1.321 4
  • EC 2.1.1'); 56
  • EC 2.1.1.77 56
  • EC 2.1.1 56

External Ids for PRMT8 Gene

Previous HGNC Symbols for PRMT8 Gene

  • HRMT1L3
  • HRMT1L4

Previous GeneCards Identifiers for PRMT8 Gene

  • GC12P003470
  • GC12P003600
  • GC12P003490

Summaries for PRMT8 Gene

Entrez Gene Summary for PRMT8 Gene

  • Arginine methylation is a widespread posttranslational modification mediated by arginine methyltransferases, such as PRMT8. Arginine methylation is involved in a number of cellular processes, including DNA repair, RNA transcription, signal transduction, protein compartmentalization, and possibly protein translation (Lee et al., 2005 [PubMed 16051612]).[supplied by OMIM, Mar 2008]

GeneCards Summary for PRMT8 Gene

PRMT8 (Protein Arginine Methyltransferase 8) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and protein heterodimerization activity. An important paralog of this gene is PRMT1.

UniProtKB/Swiss-Prot for PRMT8 Gene

  • S-adenosyl-L-methionine-dependent and membrane-associated arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA) in proteins such as NIFK, myelin basic protein, histone H4, H2A and H2A/H2B dimer (PubMed:16051612, PubMed:17925405, PubMed:26876602, PubMed:26529540). Able to mono- and dimethylate EWS protein; however its precise role toward EWS remains unclear as it still interacts with fully methylated EWS (PubMed:18320585).

Tocris Summary for PRMT8 Gene

  • Protein arginine methyltransferases are enyzmes that catalyze the transfer of methyl groups from S-adenosylmethionine (SAM) to the arginine residues on histones and other proteins. The dysregulation of this methylation is critical in the development of certain cancers.

Additional gene information for PRMT8 Gene

No data available for CIViC summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PRMT8 Gene

Genomics for PRMT8 Gene

GeneHancer (GH) Regulatory Elements for PRMT8 Gene

Promoters and enhancers for PRMT8 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12J003492 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE 600.1 +110.8 110809 3.7 ELF3 AHR TFE3 YY1 ZNF560 ZNF547 GLIS2 PRDM10 ZIC2 ZNF7 GC12P006214 PIRC53 THCAT155 PRMT8 ENSG00000243507 ENSG00000256691 GC12P006129
GH12J003380 Enhancer 0.6 Ensembl ENCODE 600.7 -0.2 -226 1.4 MAFK ZBTB17 PRMT8 LINC02417
GH12J003378 Enhancer 0.4 Ensembl 600.7 -1.9 -1948 1.6 SCRT2 SCRT1 PRMT8 LINC02417
GH12J003310 Enhancer 1.2 FANTOM5 Ensembl ENCODE dbSUPER 3.3 -69.9 -69865 1.8 CREB1 ZIC2 DPF2 ZFHX2 ELF1 MAZ ZNF687 FOS SMARCE1 PRMT8 LINC02827 GC12M003283 ENSG00000250770
GH12J003421 Enhancer 0.7 Ensembl ENCODE 0.3 +39.6 39628 2.8 SP1 ZNF341 EZH2 NANOG POU5F1 LOC105369607 GC12M003415 PRMT8
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around PRMT8 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the PRMT8 gene promoter:
  • AhR
  • Arnt
  • E2F
  • E47
  • HEN1
  • MAZR
  • Pax-3
  • Pax-6
  • SEF-1 (1)
  • YY1

Genomic Locations for PRMT8 Gene

Genomic Locations for PRMT8 Gene
chr12:3,381,349-3,593,973
(GRCh38/hg38)
Size:
212,625 bases
Orientation:
Plus strand
chr12:3,490,515-3,703,139
(GRCh37/hg19)
Size:
212,625 bases
Orientation:
Plus strand

Genomic View for PRMT8 Gene

Genes around PRMT8 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PRMT8 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PRMT8 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PRMT8 Gene

Proteins for PRMT8 Gene

  • Protein details for PRMT8 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NR22-ANM8_HUMAN
    Recommended name:
    Protein arginine N-methyltransferase 8
    Protein Accession:
    Q9NR22
    Secondary Accessions:
    • B2RDP0
    • Q8TBJ8

    Protein attributes for PRMT8 Gene

    Size:
    394 amino acids
    Molecular mass:
    45291 Da
    Quaternary structure:
    • Homodimer (PubMed:16051612, PubMed:26876602, PubMed:26529540). Tetramer; individual homodimers associates to form a homotetramer (PubMed:26529540). Homooctamer; individual homodimers associates to form a homooctamer and homooligomerization is required for proper localization to the cell membrane (PubMed:26876602). Heterodimer with PRMT1; heterodimerization may recruit PRMT1 activity to the plasma membrane (PubMed:16051612). Interacts with PRMT2 (via the SH3 domain) (PubMed:17925405). Interacts with FYN (via the SH3 domain) (PubMed:17925405). Interacts with EWS; independently of EWS methylation status (PubMed:18320585).
    SequenceCaution:
    • Sequence=AAF91390.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAG37987.1; Type=Frameshift; Positions=45; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for PRMT8 Gene

    Alternative splice isoforms for PRMT8 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for PRMT8 Gene

Selected DME Specific Peptides for PRMT8 Gene

Q9NR22:
  • HEEMLKD
  • KWLKPGG
  • LDFKGQLC
  • VTNACLIKEVDIYTVK
  • IISEWMGY
  • VLDVGSG
  • DYYFDSY
  • GIHEEML
  • KVVLDVG
  • AKAGAKKV

Post-translational modifications for PRMT8 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for PRMT8 Gene

Domains & Families for PRMT8 Gene

Gene Families for PRMT8 Gene

Protein Domains for PRMT8 Gene

Suggested Antigen Peptide Sequences for PRMT8 Gene

GenScript: Design optimal peptide antigens:
  • Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4 (ANM8_HUMAN)
  • cDNA: FLJ23133 fis, clone LNG08560 (Q9H5R7_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q9NR22

UniProtKB/Swiss-Prot:

ANM8_HUMAN :
  • The SH3-binding motifs mediate the interaction with SH3 domain-containing proteins such as PRMT2 and FYN, possibly leading to displace the N-terminal domain and activate the protein.
  • Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT8 subfamily.
Domain:
  • The SH3-binding motifs mediate the interaction with SH3 domain-containing proteins such as PRMT2 and FYN, possibly leading to displace the N-terminal domain and activate the protein.
  • The N-terminal region (1-60) inhibits the arginine N-methyltransferase activity.
Family:
  • Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT8 subfamily.
genes like me logo Genes that share domains with PRMT8: view

Function for PRMT8 Gene

Molecular function for PRMT8 Gene

UniProtKB/Swiss-Prot Function:
S-adenosyl-L-methionine-dependent and membrane-associated arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA) in proteins such as NIFK, myelin basic protein, histone H4, H2A and H2A/H2B dimer (PubMed:16051612, PubMed:17925405, PubMed:26876602, PubMed:26529540). Able to mono- and dimethylate EWS protein; however its precise role toward EWS remains unclear as it still interacts with fully methylated EWS (PubMed:18320585).
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=L-arginyl-[protein] + 2 S-adenosyl-L-methionine = 2 H(+) + N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:48096, Rhea:RHEA-COMP:10532, Rhea:RHEA-COMP:11991, ChEBI:CHEBI:15378, ChEBI:CHEBI:29965, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:61897; EC=2.1.1.319; Evidence={ECO:0000269 PubMed:16051612, ECO:0000269 PubMed:17925405, ECO:0000269 PubMed:18320585};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=L-arginyl-[protein] + S-adenosyl-L-methionine = H(+) + N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:48100, Rhea:RHEA-COMP:10532, Rhea:RHEA-COMP:11990, ChEBI:CHEBI:15378, ChEBI:CHEBI:29965, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:65280; EC=2.1.1.321; Evidence={ECO:0000269 PubMed:16051612, ECO:0000269 PubMed:17925405, ECO:0000269 PubMed:18320585};.
UniProtKB/Swiss-Prot BiophysicochemicalProperties:
Kinetic parameters: KM=1.3 uM for GRGGFGGRGGFRGGRGG-NH2 {ECO:0000269 PubMed:18320585};

Enzyme Numbers (IUBMB) for PRMT8 Gene

Phenotypes From GWAS Catalog for PRMT8 Gene

Gene Ontology (GO) - Molecular Function for PRMT8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16051612
GO:0008168 methyltransferase activity IEA --
GO:0008469 histone-arginine N-methyltransferase activity IDA 16051612
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity IDA 16051612
GO:0016740 transferase activity IEA --
genes like me logo Genes that share ontologies with PRMT8: view
genes like me logo Genes that share phenotypes with PRMT8: view

Animal Models for PRMT8 Gene

MGI Knock Outs for PRMT8:
  • Prmt8 Prmt8<tm1d(EUCOMM)Wtsi>

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PRMT8

Clone Products

  • Applied Biological Materials (abm): Clones for PRMT8 - Now 50% OFF >
  • * PRMT8 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
  • * PRMT8 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for PRMT8 Gene

Localization for PRMT8 Gene

Subcellular locations from UniProtKB/Swiss-Prot for PRMT8 Gene

Cell membrane; Lipid-anchor; Cytoplasmic side.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for PRMT8 gene
Compartment Confidence
plasma membrane 5
cytosol 4
nucleus 1

Gene Ontology (GO) - Cellular Components for PRMT8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 NOT nucleus IDA 16051612
GO:0005829 cytosol IBA 21873635
GO:0005886 plasma membrane IDA,IBA 16051612
GO:0016020 membrane IEA --
GO:0098753 anchored component of the cytoplasmic side of the plasma membrane IDA 26876602
genes like me logo Genes that share ontologies with PRMT8: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for PRMT8 Gene

Pathways & Interactions for PRMT8 Gene

PathCards logo

SuperPathways for PRMT8 Gene

No Data Available

Gene Ontology (GO) - Biological Process for PRMT8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IBA 21873635
GO:0006479 protein methylation IMP 26876602
GO:0016571 histone methylation IDA 16051612
GO:0018216 peptidyl-arginine methylation IDA 16051612
GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine IDA 16051612
genes like me logo Genes that share ontologies with PRMT8: view

No data available for Pathways by source and SIGNOR curated interactions for PRMT8 Gene

Drugs & Compounds for PRMT8 Gene

No Compound Related Data Available

Transcripts for PRMT8 Gene

mRNA/cDNA for PRMT8 Gene

Unigene Clusters for PRMT8 Gene

Protein arginine methyltransferase 8:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PRMT8

Clone Products

  • Applied Biological Materials (abm): Clones for PRMT8 - Now 50% OFF >
  • * PRMT8 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
  • * PRMT8 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All

Alternative Splicing Database (ASD) splice patterns (SP) for PRMT8 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11
SP1: - -
SP2: - - -
SP3: -

Relevant External Links for PRMT8 Gene

GeneLoc Exon Structure for
PRMT8
ECgene alternative splicing isoforms for
PRMT8

Expression for PRMT8 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for PRMT8 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for PRMT8 Gene

This gene is overexpressed in Brain - Nucleus accumbens (basal ganglia) (x7.2), Brain - Putamen (basal ganglia) (x6.9), Brain - Cortex (x6.6), Brain - Caudate (basal ganglia) (x6.2), Brain - Frontal Cortex (BA9) (x6.0), and Brain - Anterior cingulate cortex (BA24) (x5.5).

Protein differential expression in normal tissues from HIPED for PRMT8 Gene

This gene is overexpressed in Frontal cortex (61.6) and Retina (7.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for PRMT8 Gene



Protein tissue co-expression partners for PRMT8 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of PRMT8 Gene:

PRMT8

SOURCE GeneReport for Unigene cluster for PRMT8 Gene:

Hs.504530

mRNA Expression by UniProt/SwissProt for PRMT8 Gene:

Q9NR22-ANM8_HUMAN
Tissue specificity: Brain-specific.

Evidence on tissue expression from TISSUES for PRMT8 Gene

  • Nervous system(4.7)
genes like me logo Genes that share expression patterns with PRMT8: view

No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for PRMT8 Gene

Orthologs for PRMT8 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for PRMT8 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia PRMT8 35 34
  • 99.32 (n)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia PRMT8 35
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia PRMT8 35 34
  • 94.75 (n)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia PRMT8 35
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Prmt8 17 35 34
  • 93.06 (n)
rat
(Rattus norvegicus)
Mammalia Prmt8 34
  • 92.98 (n)
cow
(Bos Taurus)
Mammalia PRMT8 35 34
  • 92.89 (n)
OneToOne
chicken
(Gallus gallus)
Aves PRMT8 35 34
  • 82.15 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia PRMT8 35
  • 90 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia prmt8 34
  • 79 (n)
zebrafish
(Danio rerio)
Actinopterygii CABZ01016567.1 35
  • 81 (a)
OneToMany
prmt8b 35
  • 79 (a)
OneToMany
LOC556054 34
  • 77.07 (n)
fruit fly
(Drosophila melanogaster)
Insecta Art1 35
  • 62 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea prmt-1 35
  • 65 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes HMT1 35
  • 46 (a)
OneToMany
corn
(Zea mays)
Liliopsida Zm.2042 34
wheat
(Triticum aestivum)
Liliopsida Ta.385 34
barley
(Hordeum vulgare)
Liliopsida Hv.1977 34
rice
(Oryza sativa)
Liliopsida Os.18453 34
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2169 35
  • 68 (a)
OneToMany
Cin.4364 34
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.4364 34
Species where no ortholog for PRMT8 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)

Evolution for PRMT8 Gene

ENSEMBL:
Gene Tree for PRMT8 (if available)
TreeFam:
Gene Tree for PRMT8 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for PRMT8: view image

Paralogs for PRMT8 Gene

Paralogs for PRMT8 Gene

(6) SIMAP similar genes for PRMT8 Gene using alignment to 2 proteins:

  • ANM8_HUMAN
  • Q9H5R7_HUMAN
genes like me logo Genes that share paralogs with PRMT8: view

Variants for PRMT8 Gene

Sequence variations from dbSNP and Humsavar for PRMT8 Gene

SNP ID Clin Chr 12 pos Variation AA Info Type
rs1000015512 -- 3,422,536(+) C/T genic_upstream_transcript_variant, intron_variant
rs1000042673 -- 3,410,474(+) G/A genic_upstream_transcript_variant, intron_variant
rs1000064796 -- 3,452,602(+) C/G/T genic_upstream_transcript_variant, intron_variant
rs1000073160 -- 3,479,140(+) G/A/C genic_upstream_transcript_variant, intron_variant
rs1000075805 -- 3,540,911(+) C/T genic_upstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for PRMT8 Gene

Variant ID Type Subtype PubMed ID
dgv245e214 CNV gain 21293372
esv2293557 CNV deletion 18987734
esv2674403 CNV deletion 23128226
esv2745435 CNV deletion 23290073
esv2745436 CNV deletion 23290073
esv28881 CNV loss 19812545
esv3628345 CNV loss 21293372
esv3628346 CNV loss 21293372
esv3874 CNV loss 18987735
nsv1042348 CNV gain 25217958
nsv1071003 CNV deletion 25765185
nsv1112253 CNV deletion 24896259
nsv1150557 CNV deletion 26484159
nsv468980 CNV loss 19166990
nsv468981 CNV gain 19166990
nsv483060 CNV loss 15286789
nsv557115 CNV loss 21841781
nsv557116 CNV gain 21841781
nsv580 CNV insertion 18451855
nsv581 CNV deletion 18451855
nsv976557 CNV duplication 23825009

Variation tolerance for PRMT8 Gene

Residual Variation Intolerance Score: 19% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.29; 6.37% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for PRMT8 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
PRMT8

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PRMT8 Gene

Disorders for PRMT8 Gene

Additional Disease Information for PRMT8

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for PRMT8 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PRMT8 Gene

Publications for PRMT8 Gene

  1. Identification of proteins interacting with protein arginine methyltransferase 8: the Ewing sarcoma (EWS) protein binds independent of its methylation state. (PMID: 18320585) Pahlich S … Gehring H (Proteins 2008) 3 4 23 58
  2. Regulation of protein arginine methyltransferase 8 (PRMT8) activity by its N-terminal domain. (PMID: 17925405) Sayegh J … Clarke SG (The Journal of biological chemistry 2007) 3 4 23 58
  3. PRMT8, a new membrane-bound tissue-specific member of the protein arginine methyltransferase family. (PMID: 16051612) Lee J … Bedford MT (The Journal of biological chemistry 2005) 2 3 4 58
  4. Novel helical assembly in arginine methyltransferase 8. (PMID: 26876602) Toma-Fukai S … Shimizu T (Journal of molecular biology 2016) 3 4 58
  5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 45 58

Products for PRMT8 Gene

Sources for PRMT8 Gene

Content
Loading form....