External Ids for PRL Gene
Previous GeneCards Identifiers for PRL Gene
This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]
GeneCards Summary for PRL Gene
PRL (Prolactin) is a Protein Coding gene. Diseases associated with PRL include Empty Sella Syndrome and Sheehan Syndrome. Among its related pathways are Glucocorticoid receptor regulatory network and TGF-Beta Pathway. Gene Ontology (GO) annotations related to this gene include hormone activity and prolactin receptor binding.
UniProtKB/Swiss-Prot for PRL Gene
Prolactin acts primarily on the mammary gland by promoting lactation.