Aliases for PRKCSH Gene
Aliases for PRKCSH Gene
- Protein Kinase C Substrate 80K-H 2 3 5
- Protein Kinase C Substrate 60.1 KDa Protein Heavy Chain 3 4
- Advanced Glycation End-Product Receptor 2 2 3
- Glucosidase II Subunit Beta 3 4
- Glucosidase 2 Subunit Beta 2 3
- Hepatocystin 2 3
- G19P1 3 4
- PKCSH 3 4
- Protein Kinase C Substrate, 80 Kda Protein 3
- Glucosidase II Beta Subunit 2
External Ids for PRKCSH Gene
- HGNC: 9411
- Entrez Gene: 5589
- Ensembl: ENSG00000130175
- OMIM: 177060
- UniProtKB: P14314
Previous HGNC Symbols for PRKCSH Gene
- G19P1
- PCLD
- PLD1
Previous GeneCards Identifiers for PRKCSH Gene
- GC19P011677
- GC19P011769
- GC19P011391
- GC19P011407
- GC19P011546
- GC19P011121
Summaries for PRKCSH Gene
-
This gene encodes the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum. The encoded protein is an acidic phosphoprotein known to be a substrate for protein kinase C. Mutations in this gene have been associated with the autosomal dominant polycystic liver disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
GeneCards Summary for PRKCSH Gene
PRKCSH (Protein Kinase C Substrate 80K-H) is a Protein Coding gene. Diseases associated with PRKCSH include Polycystic Liver Disease 1 and Polycystic Liver Disease. Among its related pathways are Metabolism of proteins and Transport to the Golgi and subsequent modification. Gene Ontology (GO) annotations related to this gene include calcium ion binding and ion channel binding.
UniProtKB/Swiss-Prot for PRKCSH Gene
-
Regulatory subunit of glucosidase II.
Additional gene information for PRKCSH Gene
- Monarch Initiative
- Search for PRKCSH at DataMed
- Search for PRKCSH at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PRKCSH Gene
Genomics for PRKCSH Gene
GeneHancer (GH) Regulatory Elements for PRKCSH Gene
Promoters and enhancers for PRKCSH Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around PRKCSH on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for PRKCSH Gene
Genomic Locations for PRKCSH Gene
- chr19:11,435,257-11,450,968
- (GRCh38/hg38)
- Size:
- 15,712 bases
- Orientation:
- Plus strand
- chr19:11,546,109-11,561,783
- (GRCh37/hg19)
Genomic View for PRKCSH Gene
Genes around PRKCSH on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19p13.2 by Ensembl
- 19p13.2 by Entrez Gene
- 19p13.2 by HGNC
PRKCSH Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for PRKCSH Gene
Proteins for PRKCSH Gene
-
Protein details for PRKCSH Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P14314-GLU2B_HUMAN
- Recommended name:
- Glucosidase 2 subunit beta
- Protein Accession:
- P14314
- A8K318
- Q96BU9
- Q96D06
- Q9P0W9
Protein attributes for PRKCSH Gene
- Size:
- 528 amino acids
- Molecular mass:
- 59425 Da
- Quaternary structure:
-
- Heterodimer of a catalytic alpha subunit (GANAB) and a beta subunit (PRKCSH). Binds glycosylated PTPRC (By similarity).
- SequenceCaution:
-
- Sequence=AAH15154.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for PRKCSH Gene
Post-translational modifications for PRKCSH Gene
Other Protein References for PRKCSH Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for PRKCSH
- Novus Biologicals Antibodies for PRKCSH
-
Abcam antibodies for PRKCSH
- Invitrogen Antibodies for PRKCSH
- GeneTex PRKCSH antibody for PRKCSH
-
Santa Cruz Biotechnology (SCBT) Antibodies for PRKCSH
Protein Products
-
OriGene Purified Proteins for PRKCSH
- Search Origene for MassSpec and Protein Over-expression Lysates for PRKCSH
- Origene Custom Protein Services for PRKCSH
- Search GeneTex for Proteins for PRKCSH
-
Abcam proteins for PRKCSH
Assay Products
No data available for DME Specific Peptides for PRKCSH Gene
Domains & Families for PRKCSH Gene
Gene Families for PRKCSH Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Disease related genes
- Plasma proteins
- Predicted secreted proteins
Protein Domains for PRKCSH Gene
Suggested Antigen Peptide Sequences for PRKCSH Gene
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for PRKCSH Gene
Function for PRKCSH Gene
Molecular function for PRKCSH Gene
- GENATLAS Biochemistry:
- protein kinase C substrate 80K-H (substrate for protein kinase C)
- UniProtKB/Swiss-Prot Function:
- Regulatory subunit of glucosidase II.
Phenotypes From GWAS Catalog for PRKCSH Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003723 | RNA binding | IEA | -- |
| GO:0005080 | protein kinase C binding | IPI | 15707389 |
| GO:0005509 | calcium ion binding | IEA | -- |
| GO:0044325 | ion channel binding | IPI | 19801576 |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for PRKCSH Gene
- MGI mutant phenotypes for PRKCSH:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for PRKCSH:
-
- Increased vaccinia virus (VACV) infection
- Synthetic lethal with Ras
- Decreased viability in esophageal squamous lineage
- Increased transferrin (TF) endocytosis
- Increased shRNA abundance (Z-score > 2)
- Negative genetic interaction between KRASG13D/+ and KRAS+/-
- Decreased viability
- Decreased shRNA abundance (Z-score < -2)
- Decreased shRNA abundance
- Condensed cis-Golgi
- Decreased telomerase activity
Animal Models for PRKCSH Gene
- MGI Knock Outs for PRKCSH:
-
- Prkcsh tm1.1Som
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for PRKCSH
-
-
ViGene Biosciences lentiviral particle packaged cDNA for PRKCSH gene
-
ViGene Biosciences ready-to-package AAV shRNAs for PRKCSH gene
- Search ViGene Biosciences for PRKCSH
CRISPR Products
-
OriGene CRISPR knockouts for PRKCSH
- genomics-online: gRNA clones - Search results for available PRKCSH gene related products
- Applied Biological Materials CRISPR for PRKCSH
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for PRKCSH
- GenScript: Design CRISPR guide RNA sequences for PRKCSH
miRNA for PRKCSH Gene
- miRTarBase miRNAs that target PRKCSH
miRNA Products
- Search ViGene Biosciences for PRKCSH
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for PRKCSH
- Browse OriGene Inhibitory RNA Products For PRKCSH
- genomics-online: shRNA clones - Search results for available PRKCSH gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for PRKCSH gene
Clone Products
- Sino Biological Human cDNA Clone for PRKCSH
- VectorBuilder custom plasmid, inducible vectors for PRKCSH
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PRKCSH
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available PRKCSH gene related products
- orf clones - Search results for available PRKCSH gene related products
- Applied Biological Materials Clones for PRKCSH
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for PRKCSH
-
ViGene Biosciences adenoviral particle packaged cDNA for PRKCSH gene
-
ViGene Biosciences lentiviral particle packaged cDNA for PRKCSH gene
-
ViGene Biosciences ready-to-package AAV shRNAs for PRKCSH gene
No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for PRKCSH Gene
Localization for PRKCSH Gene
Subcellular locations from UniProtKB/Swiss-Prot for PRKCSH Gene
- Endoplasmic reticulum.
| Compartment | Confidence |
|---|---|
| endoplasmic reticulum | 5 |
- Endoplasmic reticulum (4)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005622 | intracellular | NAS | 2793184 |
| GO:0005783 | endoplasmic reticulum | IEA,IDA | 19801576 |
| GO:0005788 | endoplasmic reticulum lumen | TAS | -- |
Pathways & Interactions for PRKCSH Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Calnexin/calreticulin cycle | ||
| 2 | Innate Immune System |
.61
|
|
| 3 | Metabolism of proteins | ||
| 4 | Protein processing in endoplasmic reticulum | ||
| 5 | Advanced glycosylation endproduct receptor signaling | ||
Pathways by source for PRKCSH Gene
8 Reactome pathways for PRKCSH Gene
1 KEGG pathway for PRKCSH Gene
UniProtKB/Swiss-Prot P14314-GLU2B_HUMAN
- Pathway: Glycan metabolism; N-glycan metabolism.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001889 | liver development | IEA | -- |
| GO:0006457 | protein folding | TAS | -- |
| GO:0006491 | N-glycan processing | IEA | -- |
| GO:0006807 | nitrogen compound metabolic process | IEA | -- |
| GO:0010977 | negative regulation of neuron projection development | IEA | -- |
No data available for SIGNOR curated interactions for PRKCSH Gene
Drugs & Compounds for PRKCSH Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Cellobiose | Experimental | Pharma | 0 |
Transcripts for PRKCSH Gene
mRNA/cDNA for PRKCSH Gene
- (9) REFSEQ mRNAs :
- (12) Additional mRNA sequences :
- (1035) Selected AceView cDNA sequences:
- (20) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for PRKCSH Gene
CRISPR Products
-
OriGene CRISPR knockouts for PRKCSH
- genomics-online: gRNA clones - Search results for available PRKCSH gene related products
- Applied Biological Materials CRISPR for PRKCSH
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for PRKCSH
- GenScript: Design CRISPR guide RNA sequences for PRKCSH
miRNA Products
- Search ViGene Biosciences for PRKCSH
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for PRKCSH
- Browse OriGene Inhibitory RNA Products For PRKCSH
- genomics-online: shRNA clones - Search results for available PRKCSH gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for PRKCSH gene
Clone Products
- Sino Biological Human cDNA Clone for PRKCSH
- VectorBuilder custom plasmid, inducible vectors for PRKCSH
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PRKCSH
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available PRKCSH gene related products
- orf clones - Search results for available PRKCSH gene related products
- Applied Biological Materials Clones for PRKCSH
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | · | 5c | · | 5d | · | 5e | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b | ^ | 11a | · | 11b | · | 11c | ^ | 12a | · | 12b | ^ | 13a | · | 13b | ^ | 14 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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| SP14: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||
| SP15: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP16: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||
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| SP23: |
| ExUns: | 15 | ^ | 16a | · | 16b | · | 16c | ^ | 17a | · | 17b | · | 17c | ^ | 18a | · | 18b | ^ | 19a | · | 19b | · | 19c | · | 19d | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23a | · | 23b | ^ | 24 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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| SP4: | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||
| SP5: | - | - | - | - | |||||||||||||||||||||||||||||||||
| SP6: | - | - | - | ||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | |||||||||||||||||||||||||||||||||
| SP8: | - | - | |||||||||||||||||||||||||||||||||||
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| SP14: | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||
| SP15: | |||||||||||||||||||||||||||||||||||||
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| SP18: | |||||||||||||||||||||||||||||||||||||
| SP19: | - | ||||||||||||||||||||||||||||||||||||
| SP20: | |||||||||||||||||||||||||||||||||||||
| SP21: | |||||||||||||||||||||||||||||||||||||
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| SP23: |
Expression for PRKCSH Gene
This gene is overexpressed in Lymph node (7.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for PRKCSH Gene
NURSA nuclear receptor signaling pathways regulating expression of PRKCSH Gene:
PRKCSHSOURCE GeneReport for Unigene cluster for PRKCSH Gene:
Hs.610830Evidence on tissue expression from TISSUES for PRKCSH Gene
- Nervous system(4.9)
- Liver(4.8)
- Lung(4.8)
- Blood(4.6)
- Intestine(4.3)
- Kidney(4.3)
- Skin(4.1)
- Spleen(3.8)
- Eye(3.3)
- Muscle(2)
- Stomach(2)
- Thyroid gland(2)
Phenotype-based relationships between genes and organs from Gene ORGANizer for PRKCSH Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- cardiovascular
- digestive
- nervous
- skeletal muscle
- urinary
Regions:
Head and neck:
- ear
Thorax:
- heart
Abdomen:
- abdominal wall
- biliary tract
- kidney
- liver
General:
- blood
- blood vessel
Primer Products
-
OriGene qPCR primer pairs for PRKCSH
- genomics-online: primer clones - Search results for available PRKCSH gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for PRKCSH Gene
Orthologs for PRKCSH Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | PRKCSH 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | PRKCSH 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | PRKCSH 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Prkcsh 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Prkcsh 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | PRKCSH 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | PRKCSH 34 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | PRKCSH 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | prkcsh 33 |
|
||
| MGC75615 33 |
|
||||
| zebrafish (Danio rerio) |
Actinopterygii | prkcsh 33 34 |
|
||
| -- 33 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | CG6453 35 33 34 |
|
||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP004609 33 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | CELE_ZK1307.8 33 |
|
||
| ZK1307.8 34 |
|
OneToOne | |||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | GTB1 34 |
|
OneToOne | |
| rice (Oryza sativa) |
Liliopsida | Os.6899 33 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.2522 34 |
|
OneToMany | |
| CSA.7249 34 |
|
OneToMany |
- Species where no ortholog for PRKCSH was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for PRKCSH Gene
No data available for Paralogs for PRKCSH Gene
Variants for PRKCSH Gene
| SNP ID | Clin | Chr 19 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1047200179 | uncertain-significance, Polycystic liver disease | 11,450,779(+) | C/A/T | 3_prime_UTR_variant | |
| rs11557488 | benign, not specified, Polycystic liver disease | 11,447,460(+) | G/A/C | coding_sequence_variant, missense_variant | |
| rs115820640 | likely-benign, Polycystic liver disease | 11,435,665(+) | C/G/T | 5_prime_UTR_variant, genic_upstream_transcript_variant, upstream_transcript_variant | |
| rs121918519 | pathogenic, Congenital cystic disease of liver | 11,448,604(+) | C/T | coding_sequence_variant, stop_gained | |
| rs121918520 | pathogenic, Congenital cystic disease of liver | 11,448,917(+) | C/G/T | coding_sequence_variant, stop_gained, synonymous_variant |
Residual Variation Intolerance Score:
39% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
14.60;
96.53% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for PRKCSH Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PRKCSH Gene
Disorders for PRKCSH Gene
(9) MalaCards diseases for PRKCSH Gene - From: HGMD, OMIM, ClinVar, Orphanet, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| polycystic liver disease 1 |
|
|
| polycystic liver disease |
|
|
| liver disease |
|
|
| polycystic kidney disease 4 with or without hepatic disease |
|
|
| familial hemiplegic migraine |
|
|
Search PRKCSH in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
GLU2B_HUMAN- Polycystic liver disease 1 (PCLD1) [MIM:174050]: An autosomal dominant hepatobiliary disease characterized by overgrowth of biliary epithelium and supportive connective tissue, resulting in multiple liver cysts. {ECO:0000269 PubMed:12529853, ECO:0000269 PubMed:12577059}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for PRKCSH
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for Genatlas for PRKCSH Gene
Publications for PRKCSH Gene
- Mutations in PRKCSH cause isolated autosomal dominant polycystic liver disease. (PMID: 12529853) Li A … Somlo S (American journal of human genetics 2003) 2 3 4 22 58
- PRKCSH genetic mutation was not found in Taiwanese patients with polycystic liver disease. (PMID: 19308730) Yang AM … Yang WS (Digestive diseases and sciences 2010) 3 22 44 58
- Extensive mutational analysis of PRKCSH and SEC63 broadens the spectrum of polycystic liver disease. (PMID: 16835903) Waanders E … Drenth JP (Human mutation 2006) 3 22 44 58
- Germline mutations in PRKCSH are associated with autosomal dominant polycystic liver disease. (PMID: 12577059) Drenth JP … Jansen JB (Nature genetics 2003) 3 4 22 58
- A 3-Mb region for the familial hemiplegic migraine locus on 19p13.1-p13.2: exclusion of PRKCSH as a candidate gene. Dutch Migraine Genetic Research Group. (PMID: 9043864) Ophoff RA … Frants RR (European journal of human genetics : EJHG 1996) 3 4 22 58
Products for PRKCSH Gene
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- Custom Antibody ServicesOriGene Antibodies for PRKCSH
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- Cyagen custom Knockout/knockin (KOKI) mouse models for PRKCSH
- VectorBuilder custom plasmid, inducible vectors for PRKCSH
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- Mammalian expression: PiggyBac
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- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 90 available PRKCSH Antibodies ranked by validation data
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- antibodies-online: Search results for 9 available PRKCSH Proteins ranked by validation data
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- GeneTex PRKCSH antibody for PRKCSH
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- ViGene Biosciences adenoviral particle packaged cDNA for PRKCSH gene
- ViGene Biosciences lentiviral particle packaged cDNA for PRKCSH gene
- ViGene Biosciences ready-to-package AAV shRNAs for PRKCSH gene
- Search ViGene Biosciences for PRKCSH
- Santa Cruz Biotechnology (SCBT) Antibodies for PRKCSH
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- Santa Cruz Biotechnology (SCBT) CRISPR for PRKCSH
- Horizon Cell Lines for PRKCSH
- genomics-online: cdna clones - Search results for available PRKCSH gene related products
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- genomics-online: primer clones - Search results for available PRKCSH gene related products
- genomics-online: shRNA clones - Search results for available PRKCSH gene related products
Sources for PRKCSH Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
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- (7) GeneLoc
- (8) Gene Wiki
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- (23) PharmGKB
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- (26) UniGene
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- (28) ASD
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- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
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- (44) GAD
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- (46) HuGE
- (47) Atlas
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- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
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- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
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- (77) SIMAP
- (78) GenomeRNAi
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- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
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- (84) Vector BioLabs
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- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
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- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
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- (103) GeneReviews
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- (105) Taconic Biosciences
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- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
