Aliases for PRKACG Gene
External Ids for PRKACG Gene
Previous GeneCards Identifiers for PRKACG Gene
Cyclic AMP-dependent protein kinase (PKA) consists of two catalytic subunits and a regulatory subunit dimer. This gene encodes the gamma form of its catalytic subunit. The gene is intronless and is thought to be a retrotransposon derived from the gene for the alpha form of the PKA catalytic subunit. [provided by RefSeq, Jul 2008]
GeneCards Summary for PRKACG Gene
PRKACG (Protein Kinase CAMP-Activated Catalytic Subunit Gamma) is a Protein Coding gene. Diseases associated with PRKACG include Bleeding Disorder, Platelet-Type, 19 and Primary Pigmented Nodular Adrenocortical Disease. Among its related pathways are DAG and IP3 signaling and ADP signalling through P2Y purinoceptor 12. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is PRKACA.
UniProtKB/Swiss-Prot Summary for PRKACG Gene
Phosphorylates a large number of substrates in the cytoplasm and the nucleus.
Protein kinase A (PKA, aka cAMP-dependent protein kinase) is involved in the regulation of lipid and glucose metabolism and is a component of the signal transduction mechanism of certain GPCRs. PKA is composed of two regulatory subunits and two catalytic subunits.