This locus represents naturally occurring read-through transcription between the neighboring PRH1 (proline-rich protein HaeIII subfamily 1) and PRR4 (proline rich 4, lacrimal) genes on chromosome 12. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is thus unlikely to produce a protein product. [provided by RefSeq, Feb 2011] See more...

Aliases for PRH1-PRR4 Gene

Subcategory (RNA class) for PRH1-PRR4 Gene

lncRNA

Number of RNA Genes sources:

3 / 14

Aliases for PRH1-PRR4 Gene

  • PRH1-PRR4 Readthrough 3
  • NONHSAG010495 92
  • HSALNG0089270 167
  • HSALNG0089266 167
  • Lnc-PRR4-1 168
  • PRH1 3

External Ids for PRH1-PRR4 Gene

Previous GeneCards Identifiers for PRH1-PRR4 Gene

  • GC12U901555
  • GC12M011001
  • GC12M010847
  • GC12M012426
  • GC12M012645
  • GC12M012800
  • GC12M011004
  • GC12M011035
  • GC12M011336
  • GC12M011551
  • GC12M011742
  • GC12M011929
  • GC12M012115
  • GC12M012294

Summaries for PRH1-PRR4 Gene

Entrez Gene Summary for PRH1-PRR4 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring PRH1 (proline-rich protein HaeIII subfamily 1) and PRR4 (proline rich 4, lacrimal) genes on chromosome 12. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is thus unlikely to produce a protein product. [provided by RefSeq, Feb 2011]

GeneCards Summary for PRH1-PRR4 Gene

PRH1-PRR4 (PRH1-PRR4 Readthrough) is an RNA Gene, and is affiliated with the lncRNA class.

Additional gene information for PRH1-PRR4 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for PRH1-PRR4 Gene

Genomics for PRH1-PRR4 Gene

GeneHancer (GH) Regulatory Elements for PRH1-PRR4 Gene

Promoters and enhancers for PRH1-PRR4 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around PRH1-PRR4 on UCSC Golden Path with GeneCards custom track

Genomic Locations for PRH1-PRR4 Gene

Genomic Locations for PRH1-PRR4 Gene
chr12:10,845,849-11,171,625
(GRCh38/hg38)
Size:
325,777 bases
Orientation:
Minus strand
chr12:10,998,448-11,324,224
(GRCh37/hg19)
Size:
325,777 bases
Orientation:
Minus strand

Genomic View for PRH1-PRR4 Gene

Genes around PRH1-PRR4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PRH1-PRR4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PRH1-PRR4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PRH1-PRR4 Gene

Proteins for PRH1-PRR4 Gene

Post-translational modifications for PRH1-PRR4 Gene

No Post-translational modifications

No data available for DME Specific Peptides for PRH1-PRR4 Gene

Domains & Families for PRH1-PRR4 Gene

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for PRH1-PRR4 Gene

Function for PRH1-PRR4 Gene

Phenotypes From GWAS Catalog for PRH1-PRR4 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PRH1-PRR4 Gene

Localization for PRH1-PRR4 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for PRH1-PRR4 Gene

Pathways & Interactions for PRH1-PRR4 Gene

PathCards logo

SuperPathways for PRH1-PRR4 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for PRH1-PRR4 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for PRH1-PRR4 Gene

Drugs & Compounds for PRH1-PRR4 Gene

No Compound Related Data Available

Transcripts for PRH1-PRR4 Gene

mRNA/cDNA for PRH1-PRR4 Gene

18 RNACentral transcripts :
1 REFSEQ mRNAs :
2 NCBI additional mRNA sequence :
2 NONCODE transcripts :
3 LncBook transcripts :
16 LNCipedia transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for PRH1-PRR4 Gene

No ASD Table

Relevant External Links for PRH1-PRR4 Gene

GeneLoc Exon Structure for
PRH1-PRR4

Expression for PRH1-PRR4 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for PRH1-PRR4

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for PRH1-PRR4 Gene

Orthologs for PRH1-PRR4 Gene

No data available for Orthologs and Evolution for PRH1-PRR4 Gene

Paralogs for PRH1-PRR4 Gene

No data available for Paralogs for PRH1-PRR4 Gene

Variants for PRH1-PRR4 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for PRH1-PRR4 Gene

SNP ID Clinical significance and condition Chr 12 pos Variation AA Info Type
710271 Benign: not provided 10,908,908(-) G/A SYNONYMOUS_VARIANT,INTRON_VARIANT
714507 Benign: not provided 10,986,774(-) C/G SYNONYMOUS_VARIANT,INTRON_VARIANT
717257 Benign: not provided 10,939,193(-) T/C MISSENSE_VARIANT,INTRON_VARIANT
719366 Benign: not provided 10,939,019(-) G/A SYNONYMOUS_VARIANT,INTRON_VARIANT
724499 Likely Benign: not provided 10,882,254(-) T/C MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT

Additional dbSNP identifiers (rs#s) for PRH1-PRR4 Gene

Structural Variations from Database of Genomic Variants (DGV) for PRH1-PRR4 Gene

Variant ID Type Subtype PubMed ID
dgv1375n100 CNV loss 25217958
dgv1376n100 CNV gain+loss 25217958
dgv1377n100 CNV gain 25217958
dgv1378n100 CNV loss 25217958
dgv172e201 CNV deletion 23290073
dgv173e201 CNV deletion 23290073
dgv174e201 CNV deletion 23290073
dgv2362n54 CNV loss 21841781
dgv2363n54 CNV gain 21841781
dgv2364n54 CNV gain+loss 21841781
dgv2365n54 CNV gain 21841781
dgv2366n54 CNV gain+loss 21841781
dgv2367n54 CNV loss 21841781
dgv2368n54 CNV loss 21841781
dgv2369n54 CNV gain 21841781
dgv2370n54 CNV gain+loss 21841781
dgv2371n54 CNV loss 21841781
dgv2372n54 CNV loss 21841781
dgv251e214 CNV loss 21293372
dgv265e199 CNV deletion 23128226
dgv266e199 CNV deletion 23128226
dgv267e199 CNV deletion 23128226
dgv268e199 CNV deletion 23128226
dgv271n67 CNV loss 20364138
dgv42e19 CNV loss 19470904
dgv43e19 CNV loss 19470904
dgv453e212 CNV gain 25503493
dgv454e212 CNV gain 25503493
dgv455e212 CNV loss 25503493
dgv456e212 CNV loss 25503493
dgv457e212 CNV gain 25503493
dgv458e212 CNV gain 25503493
dgv459e212 CNV loss 25503493
dgv768n106 CNV deletion 24896259
dgv769n106 CNV deletion 24896259
dgv770n106 CNV deletion 24896259
dgv771n106 CNV deletion 24896259
dgv79e215 CNV deletion 23714750
esv1010712 CNV deletion 20482838
esv1011370 CNV insertion 20482838
esv1361137 CNV deletion 17803354
esv23283 CNV loss 19812545
esv2421447 CNV deletion 20811451
esv2421542 CNV deletion 20811451
esv24685 CNV loss 19812545
esv2570297 CNV deletion 19546169
esv26197 CNV gain 19812545
esv2660326 CNV deletion 23128226
esv2661296 CNV deletion 23128226
esv2664609 CNV deletion 23128226
esv2665068 CNV deletion 23128226
esv2668043 CNV deletion 23128226
esv2670207 CNV deletion 23128226
esv2675860 CNV deletion 23128226
esv2745543 CNV deletion 23290073
esv2745544 CNV deletion 23290073
esv2745545 CNV deletion 23290073
esv2745546 CNV deletion 23290073
esv2745548 CNV deletion 23290073
esv2745549 CNV deletion 23290073
esv2745550 CNV deletion 23290073
esv2745553 CNV deletion 23290073
esv2745554 CNV deletion 23290073
esv2759879 CNV loss 17122850
esv2760999 CNV gain+loss 21179565
esv2874902 CNV deletion 24192839
esv3159002 CNV deletion 24192839
esv3254051 CNV deletion 24192839
esv3306179 CNV mobile element insertion 20981092
esv3306327 CNV mobile element insertion 20981092
esv3309528 CNV mobile element insertion 20981092
esv3323418 CNV insertion 20981092
esv3328135 CNV insertion 20981092
esv33303 CNV gain 17666407
esv3361948 CNV duplication 20981092
esv3418271 CNV duplication 20981092
esv3419678 CNV insertion 20981092
esv3548756 CNV deletion 23714750
esv3548757 CNV deletion 23714750
esv3548758 CNV deletion 23714750
esv3580860 CNV gain 25503493
esv3628543 CNV gain 21293372
esv3628548 CNV loss 21293372
esv3628550 CNV loss 21293372
esv3628551 CNV loss 21293372
esv3628552 CNV loss 21293372
esv3628555 CNV gain 21293372
esv3628556 CNV loss 21293372
esv3628557 CNV loss 21293372
esv3628559 CNV loss 21293372
esv3628560 CNV gain 21293372
esv3628561 CNV loss 21293372
esv3628562 CNV gain 21293372
esv3628563 CNV loss 21293372
esv4169 CNV loss 18987735
esv5675 CNV loss 19470904
esv7358 CNV loss 19470904
esv8289 CNV loss 19470904
esv995298 CNV deletion 20482838
esv998570 CNV deletion 20482838
nsv1038277 CNV loss 25217958
nsv1038323 CNV loss 25217958
nsv1038709 CNV loss 25217958
nsv1050050 CNV loss 25217958
nsv1054664 CNV gain 25217958
nsv1068640 CNV deletion 25765185
nsv1069427 CNV deletion 25765185
nsv1070093 CNV deletion 25765185
nsv1070510 CNV deletion 25765185
nsv1070511 CNV deletion 25765185
nsv1070512 CNV deletion 25765185
nsv1071012 CNV deletion 25765185
nsv1112616 CNV deletion 24896259
nsv1113460 CNV deletion 24896259
nsv1113461 CNV deletion 24896259
nsv1113462 CNV deletion 24896259
nsv1116692 CNV tandem duplication 24896259
nsv1122698 CNV deletion 24896259
nsv1122699 CNV deletion 24896259
nsv1122700 CNV deletion 24896259
nsv1127248 CNV deletion 24896259
nsv1132355 CNV duplication 24896259
nsv1134198 CNV deletion 24896259
nsv1134199 CNV deletion 24896259
nsv1138101 CNV deletion 24896259
nsv1138102 CNV deletion 24896259
nsv1138104 CNV deletion 24896259
nsv1139564 CNV duplication 24896259
nsv1144607 CNV deletion 24896259
nsv1145582 CNV deletion 24896259
nsv1152020 CNV duplication 26484159
nsv1152044 CNV deletion 26484159
nsv1152771 CNV duplication 26484159
nsv1153140 CNV deletion 26484159
nsv1159978 CNV duplication 26073780
nsv1159979 CNV deletion 26073780
nsv428272 CNV gain+loss 18775914
nsv436149 CNV deletion 17901297
nsv442634 CNV loss 18776908
nsv471366 CNV gain 19718026
nsv511013 OTHER complex 20534489
nsv513355 CNV insertion 21212237
nsv514646 CNV gain+loss 21397061
nsv514647 CNV gain+loss 21397061
nsv516631 CNV loss 19592680
nsv52653 CNV deletion 16902084
nsv557482 CNV loss 21841781
nsv557486 CNV loss 21841781
nsv557487 CNV loss 21841781
nsv557488 CNV gain 21841781
nsv557489 CNV loss 21841781
nsv557497 CNV gain 21841781
nsv557501 CNV loss 21841781
nsv557522 CNV loss 21841781
nsv557525 CNV loss 21841781
nsv820968 CNV duplication 20802225
nsv826250 CNV loss 20364138
nsv832330 CNV gain 17160897
nsv8915 CNV gain 18304495
nsv8916 CNV gain 18304495
nsv8917 CNV loss 18304495
nsv951326 CNV duplication 24416366
nsv951327 CNV duplication 24416366
nsv957429 CNV deletion 24416366
nsv958654 CNV deletion 24416366
nsv958700 CNV deletion 24416366
nsv973026 CNV duplication 23825009
nsv973027 CNV duplication 23825009
nsv973028 CNV duplication 23825009
nsv975449 CNV duplication 23825009
nsv975450 CNV duplication 23825009
nsv976575 CNV duplication 23825009
nsv977132 CNV duplication 23825009
nsv983283 CNV duplication 23825009
nsv983284 CNV duplication 23825009
nsv983285 CNV duplication 23825009

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Variation tolerance and Additional Variant Information for PRH1-PRR4 Gene

Disorders for PRH1-PRR4 Gene

No disorders were found for PRH1-PRR4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for PRH1-PRR4 Gene

Publications for PRH1-PRR4 Gene

  1. GWAS of human bitter taste perception identifies new loci and reveals additional complexity of bitter taste genetics. (PMID: 23966204) Ledda M … Genick UK (Human molecular genetics 2014) 3 54
  2. Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method. (PMID: 21697133) Oshikawa M … Kato S (Investigative ophthalmology & visual science 2011) 3 54
  3. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T … Taylor TD (PloS one 2010) 3 54
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 54

No data available for Mastermind for PRH1-PRR4 Gene

Products for PRH1-PRR4 Gene

Sources for PRH1-PRR4 Gene