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Aliases for PPP4R3A Gene
Aliases for PPP4R3A Gene
External Ids for PPP4R3A Gene
- HGNC: 20219
- Entrez Gene: 55671
- Ensembl: ENSG00000100796
- OMIM: 610351
- UniProtKB: Q6IN85
Previous HGNC Symbols for PPP4R3A Gene
- KIAA2010
- SMEK1
Previous GeneCards Identifiers for PPP4R3A Gene
- GC14M091458
- GC14M092329
- GC14M092425
- GC14M092448
- GC14M093530
- GC14M091459
- GC14M091568
- GC14M091685
- GC14M091970
- GC14M092230
Summaries for PPP4R3A Gene
GeneCards Summary for PPP4R3A Gene
PPP4R3A (Protein Phosphatase 4 Regulatory Subunit 3A) is a Protein Coding gene. Among its related pathways are Glucagon signaling pathway and Integrated Breast Cancer Pathway. An important paralog of this gene is PPP4R3B.
UniProtKB/Swiss-Prot Summary for PPP4R3A Gene
-
Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphorylated on 'Ser-140' (gamma-H2AX) generated during DNA replication and required for DNA DSB repair.
Additional gene information for PPP4R3A Gene
- HGNC(20219)
- Entrez Gene(55671)
- Ensembl(ENSG00000100796)
- OMIM(610351)
- UniProtKB(Q6IN85)
- Open Targets Platform(ENSG00000100796)
- Monarch Initiative
- Search for PPP4R3A at DataMed
- Search for PPP4R3A at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for PPP4R3A Gene
Genomics for PPP4R3A Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for PPP4R3A Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around PPP4R3A on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for PPP4R3A
Genomic Locations for PPP4R3A Gene
Genomic Locations for PPP4R3A Gene
- chr14:91,457,137-91,510,554
- (GRCh38/hg38)
- Size:
- 53,418 bases
- Orientation:
- Minus strand
- chr14:91,923,955-91,976,898
- (GRCh37/hg19)
- Size:
- 52,944 bases
- Orientation:
- Minus strand
Genomic View for PPP4R3A Gene
Genes around PPP4R3A on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 14q32.12 by HGNC
- 14q32.12 by Entrez Gene
- 14q32.12 by Ensembl
PPP4R3A Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for PPP4R3A Gene
Proteins for PPP4R3A Gene
-
Protein details for PPP4R3A Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q6IN85-P4R3A_HUMAN
- Recommended name:
- Serine/threonine-protein phosphatase 4 regulatory subunit 3A
- Protein Accession:
- Q6IN85
- Q69YK6
- Q86U23
- Q86YI7
- Q8IVG1
- Q9H3F1
- Q9H7U8
- Q9NV01
- Q9NWP1
Protein attributes for PPP4R3A Gene
- Size:
- 833 amino acids
- Molecular mass:
- 95368 Da
- Quaternary structure:
-
- Serine/threonine-protein phosphatase 4 (PP4) occurs in different assemblies of the catalytic and one or more regulatory subunits. Component of the PP4 complex PPP4C-PPP4R2-PPP4R3A. Interacts with PPP4C; the interaction requires PPP4R2.
- SequenceCaution:
-
- Sequence=AAG39284.1; Type=Erroneous translation; Note=Wrong choice of frame.; Evidence={ECO:0000305}; Sequence=BAA91960.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305}; Sequence=BAA91960.1; Type=Miscellaneous discrepancy; Note=Probable intron retention.; Evidence={ECO:0000305}; Sequence=BAB14877.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305}; Sequence=BAC23106.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
Post-translational modifications for PPP4R3A Gene
Other Protein References for PPP4R3A Gene
Antibody Products
- Creative Diagnostics Anti-SMEK1 monoclonal antibody
- Novus Biologicals Antibodies for PPP4R3A
-
Abcam antibodies for PPP4R3A
- Invitrogen Antibodies for PPP4R3A (AFLGC-PPP4R3A)
-
Boster Bio Antibodies for PPP4R3A
- Sino Biological Antibodies for PPP4R3A
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for PPP4R3A
- Origene Custom Protein Services for PPP4R3A
-
Abcam proteins for PPP4R3A
No data available for DME Specific Peptides for PPP4R3A Gene
Domains & Families for PPP4R3A Gene
Gene Families for PPP4R3A Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for PPP4R3A Gene
- InterPro:
- Blocks:
-
- Collagen triple helix repeat
- ProtoNet:
Suggested Antigen Peptide Sequences for PPP4R3A Gene
- GenScript: Design optimal peptide antigens:
-
- SMEK homolog 1 (P4R3A_HUMAN)
- SMEK1 protein (Q8N6W1_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q6IN85- Family:
-
- Belongs to the SMEK family.
Function for PPP4R3A Gene
Molecular function for PPP4R3A Gene
- UniProtKB/Swiss-Prot Function:
- Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphorylated on 'Ser-140' (gamma-H2AX) generated during DNA replication and required for DNA DSB repair.
Phenotypes From GWAS Catalog for PPP4R3A Gene
Phenotypes for PPP4R3A Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for PPP4R3A - Select products 50% OFF >
- * PPP4R3A CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for PPP4R3A
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for PPP4R3A
miRNA for PPP4R3A Gene
- miRTarBase miRNAs that target PPP4R3A
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PPP4R3A
- Browse OriGene Inhibitory RNA Products For PPP4R3A
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Clone Products
- Applied Biological Materials (abm): Clones for PPP4R3A - Select products 50% OFF >
- * PPP4R3A as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for PPP4R3A
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PPP4R3A
Cell Line Products
-
Horizon Cell Lines for PPP4R3A
No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for PPP4R3A Gene
Localization for PPP4R3A Gene
Subcellular locations from UniProtKB/Swiss-Prot for PPP4R3A Gene
- Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Note=In interphase localized in the cytoplasm and in the nucleus (with higher levels). During metaphase located in pericentriolar regions.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 4 |
| cytoskeleton | 3 |
| plasma membrane | 1 |
| extracellular | 1 |
| mitochondrion | 1 |
| lysosome | 1 |
| peroxisome | 0 |
- Cytosol (3)
- Nuclear speckles (3)
- Nucleoplasm (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005815 | microtubule organizing center | IEA | -- |
| GO:0005829 | cytosol | IDA | -- |
Pathways & Interactions for PPP4R3A Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Glucagon signaling pathway | ||
| 2 | Integrated Breast Cancer Pathway | ||
Pathways by source for PPP4R3A Gene
1 BioSystems pathway for PPP4R3A Gene
1 KEGG pathway for PPP4R3A Gene
Interacting Proteins for PPP4R3A Gene
Selected Interacting proteins:
Q6IN85-P4R3A_HUMAN
ENSP00000450864
for PPP4R3A Gene via
MINT
STRING
IID
GPS-Prot Interaction Network for PPP4R3A
Transcripts for PPP4R3A Gene
mRNA/cDNA for PPP4R3A Gene
- 5 REFSEQ mRNAs :
- 14 NCBI additional mRNA sequence :
- 12 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000554308 2515 nts (view in UCSC)
- ENST00000554390 2953 nts (view in UCSC)
- ENST00000554511 580 nts (view in UCSC)
- ENST00000554574 1944 nts (view in UCSC)
- ENST00000554684 4108 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for PPP4R3A - Select products 50% OFF >
- * PPP4R3A CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for PPP4R3A
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for PPP4R3A
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PPP4R3A
- Browse OriGene Inhibitory RNA Products For PPP4R3A
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PPP4R3A
Clone Products
- Applied Biological Materials (abm): Clones for PPP4R3A - Select products 50% OFF >
- * PPP4R3A as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for PPP4R3A
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PPP4R3A
Relevant External Links for PPP4R3A Gene
- GeneLoc Exon Structure for
- PPP4R3A
Expression for PPP4R3A Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Bone (Muscoskeletal System)
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for PPP4R3A
Evidence on tissue expression from TISSUES for PPP4R3A Gene
- Nervous system(4.5)
- Intestine(4.5)
- Liver(4.4)
- Eye(4.2)
- Skin(2.4)
- Kidney(2.4)
- Blood(2.1)
- Muscle(2.1)
- Heart(2)
Primer Products
-
OriGene qPCR primer pairs for PPP4R3A
Gene Expression Assay Products
No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for PPP4R3A Gene
Orthologs for PPP4R3A Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | SMEK1 30 31 |
|
OneToMany | |
| -- 31 |
|
OneToMany | |||
| Dog (Canis familiaris) |
Mammalia | SMEK1 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | SMEK1 30 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | SMEK1 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Smek1 30 31 |
|
OneToOne | |
| Ppp4r3a 17 |
|
||||
| Oppossum (Monodelphis domestica) |
Mammalia | SMEK1 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Smek1 30 |
|
||
| Chicken (Gallus gallus) |
Aves | SMEK1 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | SMEK1 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | LOC100485426 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | smek1 30 31 |
|
OneToOne | |
| wufj55c11 30 |
|
||||
| Fruit Fly (Drosophila melanogaster) |
Insecta | flfl 31 |
|
OneToMany | |
| Worm (Caenorhabditis elegans) |
Secernentea | smk-1 30 31 |
|
OneToMany | |
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | PSY2 31 |
|
OneToMany | |
| Thale Cress (Arabidopsis thaliana) |
eudicotyledons | AT3G06670 30 |
|
||
| Rice (Oryza sativa) |
Liliopsida | Os01g0337600 30 |
|
||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany | |
| Fission Yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | SPBC216.01c 30 |
|
||
| Bread mold (Neurospora crassa) |
Ascomycetes | NCU11315 30 |
|
||
| Sea Vase (Ciona intestinalis) |
Ascidiacea | Cin.4515 30 |
|
- Species where no ortholog for PPP4R3A was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for PPP4R3A Gene
- ENSEMBL:
- Gene Tree for PPP4R3A (if available)
- TreeFam:
- Gene Tree for PPP4R3A (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for PPP4R3A: view image
Paralogs for PPP4R3A Gene
Variants for PPP4R3A Gene
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2333297 | CNV | deletion | 18987734 |
| esv2555842 | CNV | deletion | 19546169 |
| esv2662799 | CNV | deletion | 23128226 |
| esv3635324 | CNV | loss | 21293372 |
| nsv472301 | CNV | novel sequence insertion | 20440878 |
Residual Variation Intolerance Score:
4.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.40;
27.50% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for PPP4R3A Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- PPP4R3A
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for PPP4R3A Gene
Disorders for PPP4R3A Gene
Additional Disease Information for PPP4R3A
No disorders were found for PPP4R3A Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PPP4R3A Gene
Publications for PPP4R3A Gene
- Depletion of protein phosphatase 4 in human cells reveals essential roles in centrosome maturation, cell migration and the regulation of Rho GTPases. (PMID: 18487071) Martin-Granados C … Cohen PT (The international journal of biochemistry & cell biology 2008) 2 3 4
- A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity. (PMID: 16085932) Gingras AC … Aebersold R (Molecular & cellular proteomics : MCP 2005) 2 3 4
- A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication. (PMID: 18614045) Chowdhury D … Lieberman J (Molecular cell 2008) 3 4
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
ExternalLinks
Products for PPP4R3A Gene
- Custom Antibody Services
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- OriGene qPCR primer pairs for PPP4R3A
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- Sino Biological Human cDNA Clone for PPP4R3A
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- Sino Biological Antibodies for PPP4R3A
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- Novus Biologicals Antibodies for PPP4R3A
- Novus Biologicals proteins and lysates for PPP4R3A
- Browse Antibodies
- Browse Peptides and Proteins
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- Abcam antibodies for PPP4R3A
- Abcam proteins for PPP4R3A
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- Browse Primary Antibodies
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- Browse Proteins and Peptides
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- Browse Monoclonal Antibodies
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- Invitrogen Antibodies for PPP4R3A (AFLGC-PPP4R3A)
- VectorBuilder Custom and pre-made DNA vectors for PPP4R3A (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for PPP4R3A (ie. lentivirus, AAV, adenovirus)
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- VectorBuilder Virus packaging for PPP4R3A CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for PPP4R3A
- antibodies-online: Show 8 available SMEK1 Antibodies ranked by validation data
- Compare Top SMEK1 Antibodies
- antibodies-online: Search results for available SMEK1 related products ranked by validation data
- antibodies-online: Show 4 available SMEK1 Proteins ranked by validation data
- Compare Top SMEK1 Proteins
- Horizon Cell Lines for PPP4R3A
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for PPP4R3A
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- Boster Bio Antibodies for PPP4R3A
- Browse Boster Bio ELISA Kits
Sources for PPP4R3A Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB