Aliases for PPP4R3A Gene
External Ids for PPP4R3A Gene
Previous HGNC Symbols for PPP4R3A Gene
Previous GeneCards Identifiers for PPP4R3A Gene
GeneCards Summary for PPP4R3A Gene
PPP4R3A (Protein Phosphatase 4 Regulatory Subunit 3A) is a Protein Coding gene. Diseases associated with PPP4R3A include Spinal Muscular Atrophy, Type Iii. Among its related pathways are Integrated Breast Cancer Pathway and Glucagon signaling pathway. An important paralog of this gene is PPP4R3B.
UniProtKB/Swiss-Prot Summary for PPP4R3A Gene
Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.