Aliases for PPP4R1 Gene
External Ids for PPP4R1 Gene
Previous GeneCards Identifiers for PPP4R1 Gene
This gene encodes one of several alternate regulatory subunits of serine/threonine protein phosphatase 4 (PP4). The protein features multiple HEAT repeats. This protein forms a complex with PP4RC. This complex may have a distinct role from other PP4 complexes, including regulation of HDAC3 (Zhang et al., PMID: 15805470). There is also a transcribed pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
GeneCards Summary for PPP4R1 Gene
PPP4R1 (Protein Phosphatase 4 Regulatory Subunit 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include binding. An important paralog of this gene is PPP2R1B.
UniProtKB/Swiss-Prot Summary for PPP4R1 Gene
Regulatory subunit of serine/threonine-protein phosphatase 4. May play a role in regulation of cell division in renal glomeruli. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3.