Aliases for PPP2R5D Gene
External Ids for PPP2R5D Gene
Previous GeneCards Identifiers for PPP2R5D Gene
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for PPP2R5D Gene
PPP2R5D (Protein Phosphatase 2 Regulatory Subunit B'Delta) is a Protein Coding gene. Diseases associated with PPP2R5D include Mental Retardation, Autosomal Dominant 35 and Ppp2r5d-Related Neurodevelopmental Disorder. Among its related pathways are Beta-Adrenergic Signaling and Downstream signaling events of B Cell Receptor (BCR). Gene Ontology (GO) annotations related to this gene include binding. An important paralog of this gene is PPP2R5C.
UniProtKB/Swiss-Prot Summary for PPP2R5D Gene
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.