Aliases for PPP2R2C Gene
- Protein Phosphatase 2 Regulatory Subunit Bgamma 2 3 5
- PP2A Subunit B Isoform Gamma 2 4
- B55gamma 2 3
- IMYPNO1 3 4
- IMYPNO 2 3
- PR55G 2 3
- PR52 2 3
- Serine/Threonine-Protein Phosphatase 2A 55 KDa Regulatory Subunit B Gamma Isoform 4
- Protein Phosphatase 2 (Formerly 2A), Regulatory Subunit B (PR 52), Gamma Isoform 2
External Ids for PPP2R2C Gene
Previous GeneCards Identifiers for PPP2R2C Gene
The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for PPP2R2C Gene
PPP2R2C (Protein Phosphatase 2 Regulatory Subunit Bgamma) is a Protein Coding gene. Diseases associated with PPP2R2C include Inflammatory Bowel Disease 7 and Inflammatory Bowel Disease 3. Among its related pathways are Ceramide Pathway and Cyclins and Cell Cycle Regulation. An important paralog of this gene is PPP2R2B.
UniProtKB/Swiss-Prot Summary for PPP2R2C Gene
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
Protein Ser/Thr phosphatases are a group of enzymes that catalyze the removal of phosphate groups from serine and/or threonine residues by hydrolysis of phosphoric acid monoesters. They oppose the action of kinases and phosphorylases and are involved in signal transduction.