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PPP1R36 (Protein Phosphatase 1 Regulatory Subunit 36) is a Protein Coding gene. Diseases associated with PPP1R36 include Spermatogenic Failure 9. Gene Ontology (GO) annotations related to this gene include phosphatase binding and protein phosphatase inhibitor activity.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0004864 | protein phosphatase inhibitor activity | IEA | -- |
GO:0019902 | phosphatase binding | IEA | -- |
Symbol | External ID(s) | Details |
---|---|---|
PPP1CA |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0010923 | negative regulation of phosphatase activity | IEA,IDA | 19389623 |
GO:0032515 | negative regulation of phosphoprotein phosphatase activity | IEA | -- |
ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | · | 10c | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | - | |||||||||||||||||||||||||||||||
SP2: | |||||||||||||||||||||||||||||||||||
SP3: | - | ||||||||||||||||||||||||||||||||||
SP4: |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | PPP1R36 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | PPP1R36 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | PPP1R36 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Ppp1r36 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Ppp1r36 30 17 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | PPP1R36 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | PPP1R36 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | PPP1R36 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | PPP1R36 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | ppp1r36 30 |
|
SNP ID | Clinical significance and condition | Chr 14 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs116108142 | Benign: not provided | 64,589,188(+) |
C/T NM_172365.3(PPP1R36):c.1119C>T (p.Asn373=) |
SYNONYMOUS | |
rs142499430 | Benign: not provided | 64,550,943(+) |
T/A NM_172365.3(PPP1R36):c.92T>A (p.Met31Lys) |
MISSENSE | |
rs74056311 | Benign: not provided | 64,564,791(+) |
G/T NM_172365.3(PPP1R36):c.223G>T (p.Gly75Cys) |
MISSENSE | |
rs45482504 | - |
p.Phe267Leu |
|||
rs6573560 | - |
p.Thr83Ile |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv25548 | CNV | gain | 19812545 |
esv2748779 | CNV | deletion | 23290073 |
esv3581226 | CNV | loss | 25503493 |
esv3634754 | CNV | gain | 21293372 |
nsv1049097 | CNV | gain | 25217958 |
nsv1160195 | CNV | duplication | 26073780 |
nsv1308 | CNV | insertion | 18451855 |
nsv442343 | CNV | gain | 18776908 |
nsv564907 | CNV | gain | 21841781 |
nsv564908 | CNV | gain | 21841781 |
nsv564909 | CNV | gain | 21841781 |
Disorder | Aliases | PubMed IDs |
---|---|---|
spermatogenic failure 9 |
|
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