Aliases for PPP1R2P1 Gene

Aliases for PPP1R2P1 Gene

  • Protein Phosphatase 1 Regulatory Inhibitor Subunit 2 Pseudogene 1 2 3 5
  • Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 2 Pseudogene 1 2
  • Protein Phosphatase 1, Regulatory Subunit 2 Pseudogene 1 4
  • Putative Protein Phosphatase Inhibitor 2-Like Protein 1 4
  • PPP1R2P 3
  • IPP-2P 3

External Ids for PPP1R2P1 Gene

Previous HGNC Symbols for PPP1R2P1 Gene

  • PPP1R2P

Previous GeneCards Identifiers for PPP1R2P1 Gene

  • GC06U990099
  • GC06M032615
  • GC06M032891
  • GC06M032952
  • GC06M032847
  • GC06M032895

Summaries for PPP1R2P1 Gene

GeneCards Summary for PPP1R2P1 Gene

PPP1R2P1 (Protein Phosphatase 1 Regulatory Inhibitor Subunit 2 Pseudogene 1) is a Pseudogene. Gene Ontology (GO) annotations related to this gene include protein phosphatase inhibitor activity.

UniProtKB/Swiss-Prot Summary for PPP1R2P1 Gene

Additional gene information for PPP1R2P1 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for PPP1R2P1 Gene

Genomics for PPP1R2P1 Gene

GeneHancer (GH) Regulatory Elements for PPP1R2P1 Gene

Promoters and enhancers for PPP1R2P1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06J032879 Promoter 0.6 Ensembl 500.7 +0.3 273 0.4 CTBP1 SUZ12 EZH2 YY1 RFX1 PPP1R2P1 lnc-PSMB9-13
GH06J032965 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 5.1 -90.6 -90595 10.4 RXRA EP300 FOXK2 HNRNPK ZNF217 CTCF ZSCAN5C SIN3A TCF12 NRF1 BRD2 HLA-DMA ENSG00000223837 NONHSAG045804.2 LEMD2 VPS52 RING1 RXRB HCG25 ATF6B
GH06J032939 Promoter/Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 5.8 -63.7 -63723 9.6 ZBTB40 CTCF SIN3A USF1 SP1 TEAD4 FOS EP300 TRIM28 REST HLA-DMA BRD2 PSMB9 TAP1 TAP2 PSMB8 RING1 HLA-DMB HLA-DOB ENSG00000223837
GH06J033026 Enhancer 1.3 FANTOM5 ENCODE dbSUPER 4.8 -149.6 -149567 5.5 HNRNPK SIN3A SP1 EP300 FOS RELA RCOR1 TRIM22 POLR2A NFYB lnc-HLA-DOA-2 lnc-HLA-DPB1-13 HLA-DMA HLA-DQB1 HLA-DPA1 HLA-DPB1 HLA-DQB2 HLA-DQA2 HLA-DOA PSMB8
GH06J033056 Enhancer 0.9 Ensembl ENCODE dbSUPER 4.5 -177.6 -177627 2.6 POLR2A NFYB POU2F2 TBP RFX5 TAF1 NFATC1 MTA3 SPI1 HLF piR-45471-522 piR-36260-066 piR-59409-072 piR-56759-484 piR-61028-493 HLA-DPA1 RPL32P1 HSD17B8 RNY4P10 RXRB
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around PPP1R2P1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for PPP1R2P1 Gene

Genomic Locations for PPP1R2P1 Gene
chr6:32,876,475-32,880,074
(GRCh38/hg38)
Size:
3,600 bases
Orientation:
Minus strand
chr6:32,844,255-32,847,851
(GRCh37/hg19)
Size:
3,597 bases
Orientation:
Minus strand

Genomic View for PPP1R2P1 Gene

Genes around PPP1R2P1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PPP1R2P1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PPP1R2P1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for PPP1R2P1 Gene

  • Protein details for PPP1R2P1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96PQ5-IPP2L_HUMAN
    Recommended name:
    Putative protein phosphatase inhibitor 2-like protein 1
    Protein Accession:
    Q96PQ5

    Protein attributes for PPP1R2P1 Gene

    Size:
    205 amino acids
    Molecular mass:
    22863 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PPP1R2P1 Gene

Post-translational modifications for PPP1R2P1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for PPP1R2P1 Gene

Domains & Families for PPP1R2P1 Gene

Protein Domains for PPP1R2P1 Gene

Blocks:
  • Protein phosphatase inhibitor 2 (IPP-2)
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for PPP1R2P1 Gene

GenScript: Design optimal peptide antigens:
  • Protein phosphatase 1, regulatory subunit 2 pseudogene 1 (IPP2L_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q96PQ5

UniProtKB/Swiss-Prot:

IPP2L_HUMAN :
  • Belongs to the protein phosphatase inhibitor 2 family.
Family:
  • Belongs to the protein phosphatase inhibitor 2 family.
genes like me logo Genes that share domains with PPP1R2P1: view

No data available for Gene Families for PPP1R2P1 Gene

Function for PPP1R2P1 Gene

Molecular function for PPP1R2P1 Gene

UniProtKB/Swiss-Prot Function:
Inhibitor of protein-phosphatase 1.
GENATLAS Biochemistry:
protein phosphatase 1,regulatory (inhibitor) subunit 2,pseudogene 1 (IPP-2)

Phenotypes From GWAS Catalog for PPP1R2P1 Gene

Gene Ontology (GO) - Molecular Function for PPP1R2P1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004864 protein phosphatase inhibitor activity IBA 21873635
genes like me logo Genes that share ontologies with PPP1R2P1: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PPP1R2P1 Gene

Localization for PPP1R2P1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for PPP1R2P1 Gene

Pathways & Interactions for PPP1R2P1 Gene

PathCards logo

SuperPathways for PPP1R2P1 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for PPP1R2P1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005977 glycogen metabolic process IEA --
GO:0009966 regulation of signal transduction IEA --
GO:0032515 negative regulation of phosphoprotein phosphatase activity IEA --
GO:0043666 regulation of phosphoprotein phosphatase activity IBA 21873635
genes like me logo Genes that share ontologies with PPP1R2P1: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for PPP1R2P1 Gene

Drugs & Compounds for PPP1R2P1 Gene

No Compound Related Data Available

Transcripts for PPP1R2P1 Gene

mRNA/cDNA for PPP1R2P1 Gene

1 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for PPP1R2P1 Gene

No ASD Table

Relevant External Links for PPP1R2P1 Gene

GeneLoc Exon Structure for
PPP1R2P1

Expression for PPP1R2P1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for PPP1R2P1 Gene

mRNA differential expression in normal tissues according to GTEx for PPP1R2P1 Gene

This gene is overexpressed in Brain - Substantia nigra (x4.6) and Whole Blood (x4.1).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for PPP1R2P1

SOURCE GeneReport for Unigene cluster for PPP1R2P1 Gene:

Hs.730139
genes like me logo Genes that share expression patterns with PPP1R2P1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for PPP1R2P1 Gene

Orthologs for PPP1R2P1 Gene

Evolution for PPP1R2P1 Gene

ENSEMBL:
Gene Tree for PPP1R2P1 (if available)
TreeFam:
Gene Tree for PPP1R2P1 (if available)

No data available for Orthologs for PPP1R2P1 Gene

Paralogs for PPP1R2P1 Gene

(3) SIMAP similar genes for PPP1R2P1 Gene using alignment to 1 proteins:

  • IPP2L_HUMAN
genes like me logo Genes that share paralogs with PPP1R2P1: view

No data available for Paralogs for PPP1R2P1 Gene

Variants for PPP1R2P1 Gene

Additional Variant Information for PPP1R2P1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
PPP1R2P1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for PPP1R2P1 Gene

Disorders for PPP1R2P1 Gene

Additional Disease Information for PPP1R2P1

No disorders were found for PPP1R2P1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PPP1R2P1 Gene

Publications for PPP1R2P1 Gene

  1. Cloning of a cDNA encoding an isoform of human protein phosphatase inhibitor 2 from vascularized breast tumor. (PMID: 11696978) Wu I … Moses MA (DNA sequence : the journal of DNA sequencing and mapping 2001) 2 3 4 54
  2. Cloning and characterization of human phosphatase inhibitor-2 (IPP-2) sequences. (PMID: 7949733) Sanséau P … Trowsdale J (Mammalian genome : official journal of the International Mammalian Genome Society 1994) 2 3 54
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3 54
  4. The sequence of the human genome. (PMID: 11181995) Venter JC … Zhu X (Science (New York, N.Y.) 2001) 3 54
  5. Evolutionary dynamics of non-coding sequences within the class II region of the human MHC. (PMID: 8568858) Beck S … Trowsdale J (Journal of molecular biology 1996) 3 54

Products for PPP1R2P1 Gene

Sources for PPP1R2P1 Gene