Aliases for PPP1R2 Gene
External Ids for PPP1R2 Gene
Previous GeneCards Identifiers for PPP1R2 Gene
Protein phosphatase-1 (PP1) is one of the main eukaryotic serine/threonine phosphatases. The protein encoded by this gene binds to the catalytic subunit of PP1, strongly inhibiting its activity. Ten related pseudogenes have been found throughout the human genome. Several splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
GeneCards Summary for PPP1R2 Gene
PPP1R2 (Protein Phosphatase 1 Regulatory Inhibitor Subunit 2) is a Protein Coding gene. Diseases associated with PPP1R2 include Pneumoconiosis Due To Talc and Cataract 11, Multiple Types. Among its related pathways are Beta-Adrenergic Signaling and Apoptotic Pathways in Synovial Fibroblasts. Gene Ontology (GO) annotations related to this gene include protein phosphatase inhibitor activity and protein serine/threonine phosphatase inhibitor activity. An important paralog of this gene is PPP1R2B.
UniProtKB/Swiss-Prot Summary for PPP1R2 Gene
Inhibitor of protein-phosphatase 1.