Aliases for PPP1R1B Gene
External Ids for PPP1R1B Gene
Previous GeneCards Identifiers for PPP1R1B Gene
This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
GeneCards Summary for PPP1R1B Gene
PPP1R1B (Protein Phosphatase 1 Regulatory Inhibitor Subunit 1B) is a Protein Coding gene. Diseases associated with PPP1R1B include Heart Disease and Schizophrenia. Among its related pathways are Beta-Adrenergic Signaling and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include protein phosphatase inhibitor activity. An important paralog of this gene is PPP1R1A.
UniProtKB/Swiss-Prot Summary for PPP1R1B Gene
Inhibitor of protein-phosphatase 1.