Aliases for PPP1R17 Gene
External Ids for PPP1R17 Gene
Previous HGNC Symbols for PPP1R17 Gene
The protein encoded by this gene is found primarily in cerebellar Purkinje cells, where it functions as a protein phosphatase inhibitor. The encoded protein is a substrate for cGMP-dependent protein kinase. An allele of this gene was discovered that increases susceptibility to hypercholesterolemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
GeneCards Summary for PPP1R17 Gene
PPP1R17 (Protein Phosphatase 1 Regulatory Subunit 17) is a Protein Coding gene. Diseases associated with PPP1R17 include Hypercholesterolemia, Familial. Among its related pathways are Long-term depression. Gene Ontology (GO) annotations related to this gene include protein phosphatase inhibitor activity and phosphatase inhibitor activity.
UniProtKB/Swiss-Prot for PPP1R17 Gene
Inhibits phosphatase activities of protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A) complexes.