Aliases for PPP1R14D Gene
External Ids for PPP1R14D Gene
Previous GeneCards Identifiers for PPP1R14D Gene
Protein phosphatase-1 (PP1; see MIM 176875) is a major cellular phosphatase that reverses serine/threonine protein phosphorylation. PPP1R14D is a PP1 inhibitor that itself is regulated by phosphorylation (Liu et al., 2004 [PubMed 12974676]).[supplied by OMIM, Feb 2010]
GeneCards Summary for PPP1R14D Gene
PPP1R14D (Protein Phosphatase 1 Regulatory Inhibitor Subunit 14D) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include protein phosphatase inhibitor activity. An important paralog of this gene is PPP1R14B.
UniProtKB/Swiss-Prot Summary for PPP1R14D Gene
Inhibitor of PPP1CA. Has inhibitory activity only when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.