Aliases for PPP1R10 Gene
Aliases for PPP1R10 Gene
- Protein Phosphatase 1 Regulatory Subunit 10 2 3 5
- Phosphatase 1 Nuclear Targeting Subunit 2 3 4
- Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 10 2 3
- MHC Class I Region Proline-Rich Protein CAT53 3 4
- HLA-C Associated Transcript 53 2 3
- PP1-Binding Protein Of 114 KDa 3 4
- CAT53 3 4
- PNUTS 3 4
- FB19 3 4
External Ids for PPP1R10 Gene
- HGNC: 9284
- Entrez Gene: 5514
- Ensembl: ENSG00000204569
- OMIM: 603771
- UniProtKB: Q96QC0
Previous GeneCards Identifiers for PPP1R10 Gene
- GC06M030623
- GC06M030338
- GC06M030674
- GC06M030677
Summaries for PPP1R10 Gene
-
This gene encodes a protein phosphatase 1 binding protein. The encoded protein plays a role in many cellular processes including cell cycle progression, DNA repair and apoptosis by regulating the activity of protein phosphatase 1. This gene lies within the major histocompatibility complex class I region on chromosome 6, and alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]
GeneCards Summary for PPP1R10 Gene
PPP1R10 (Protein Phosphatase 1 Regulatory Subunit 10) is a Protein Coding gene. Diseases associated with PPP1R10 include Melanoma, Cutaneous Malignant 1. Among its related pathways are Beta-Adrenergic Signaling and Activation of cAMP-Dependent PKA. Gene Ontology (GO) annotations related to this gene include protein phosphatase inhibitor activity. An important paralog of this gene is PRR3.
UniProtKB/Swiss-Prot for PPP1R10 Gene
-
Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) homopolymers (By similarity).
Additional gene information for PPP1R10 Gene
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PPP1R10 Gene
Genomics for PPP1R10 Gene
GeneHancer (GH) Regulatory Elements for PPP1R10 Gene
Promoters and enhancers for PPP1R10 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around PPP1R10 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for PPP1R10 Gene
Genomic Locations for PPP1R10 Gene
- chr6:30,600,400-30,618,612
- (GRCh38/hg38)
- Size:
- 18,213 bases
- Orientation:
- Minus strand
- chr6:30,568,177-30,586,389
- (GRCh37/hg19)
Genomic View for PPP1R10 Gene
Genes around PPP1R10 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p21.33 by Ensembl
- 6p21.33 by Entrez Gene
- 6p21.33 by HGNC
PPP1R10 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for PPP1R10 Gene
Proteins for PPP1R10 Gene
-
Protein details for PPP1R10 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96QC0-PP1RA_HUMAN
- Recommended name:
- Serine/threonine-protein phosphatase 1 regulatory subunit 10
- Protein Accession:
- Q96QC0
- O00405
Protein attributes for PPP1R10 Gene
- Size:
- 940 amino acids
- Molecular mass:
- 99058 Da
- Quaternary structure:
-
- Component of the PTW/PP1 phosphatase complex, composed of PPP1R10/PNUTS, TOX4, WDR82, and PPP1CA or PPP1CB or PPP1CC. Interacts with PPP1CC. Interacts with PPP1CA, WDR82 and TOX4 (By similarity).
Protein Expression for PPP1R10 Gene
Post-translational modifications for PPP1R10 Gene
- Phosphorylated on Ser-398 by PKA within the region necessary for interaction with PPP1CA.
- Ubiquitination at Lys13 and Lys33
- Modification sites at PhosphoSitePlus
Other Protein References for PPP1R10 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for PPP1R10 (PNUTS)
-
Custom Antibody ServicesOriGene Antibodies for PPP1R10
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Abcam antibodies for PPP1R10
- Invitrogen Antibodies for PPP1R10
- Search GeneTex for Antibodies for PPP1R10
-
Santa Cruz Biotechnology (SCBT) Antibodies for PPP1R10
Protein Products
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OriGene Purified Proteins for PPP1R10
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-
Abcam proteins for PPP1R10
Assay Products
No data available for DME Specific Peptides for PPP1R10 Gene
Domains & Families for PPP1R10 Gene
Gene Families for PPP1R10 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for PPP1R10 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for PPP1R10 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for PPP1R10 Gene
Function for PPP1R10 Gene
Molecular function for PPP1R10 Gene
- UniProtKB/Swiss-Prot Function:
- Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) homopolymers (By similarity).
Phenotypes From GWAS Catalog for PPP1R10 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | -- |
| GO:0003723 | RNA binding | IEA,HDA | 22681889 |
| GO:0004864 | protein phosphatase inhibitor activity | IEA | -- |
| GO:0005515 | protein binding | IPI | 15231748 |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for PPP1R10 Gene
- MGI mutant phenotypes for PPP1R10:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for PPP1R10:
-
- Increased vaccinia virus (VACV) infection
- Mildly decreased CFP-tsO45G cell surface transport
- Decreased viability in esophageal squamous lineage
- Decreased viability ratio
- Decreased shRNA abundance (Z-score < -2)
- Decreased NF-kappaB reporter expression
- Increased transferrin (TF) endocytosis
- Increased shRNA abundance (Z-score > 2)
- Decreased viability with paclitaxel
- Decreased IL-8 secretion
- Synthetic lethal with MLN4924 (a NAE inhibitor)
- Decreased Salmonella enterica Typhimurium invasion
- Increased cell death HMECs cells
- Synthetic lethal with vaccinia virus (VACV) infection
- Increased viability with MLN4924 (a NAE inhibitor)
- Decreased interferon-beta reporter expression
- Decreased DCP1a protein expression and assembly in processing bodies after arsenite stimulation
- Decreased Salmonella-containing vacuole maturation
- Decreased Salmonella enterica Typhimurium membrane closure
- Decreased viability
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for PPP1R10 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for PPP1R10 gene
- Search ViGene Biosciences for PPP1R10
CRISPR Products
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OriGene CRISPR knockouts for PPP1R10
- genomics-online: gRNA clones - Search results for available PPP1R10 gene related products
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-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for PPP1R10
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miRNA for PPP1R10 Gene
- miRTarBase miRNAs that target PPP1R10
-
- hsa-mir-34a-5p (MIRT007193)
- hsa-mir-335-5p (MIRT017879)
- hsa-mir-30a-5p (MIRT028486)
- hsa-mir-1914-3p (MIRT035778)
- hsa-mir-615-3p (MIRT040376)
- hsa-mir-324-3p (MIRT042999)
- hsa-let-7e-5p (MIRT051563)
- hsa-mir-383-5p (MIRT438194)
- hsa-mir-4291 (MIRT528124)
- hsa-mir-98-3p (MIRT528126)
- hsa-let-7f-1-3p (MIRT528127)
- hsa-let-7b-3p (MIRT528128)
- hsa-let-7a-3p (MIRT528129)
- hsa-mir-4769-5p (MIRT528130)
- hsa-mir-4654 (MIRT528131)
- hsa-mir-194-3p (MIRT528132)
- hsa-mir-7157-5p (MIRT528133)
- hsa-mir-4310 (MIRT528134)
- hsa-mir-4666a-3p (MIRT528135)
- hsa-mir-381-3p (MIRT528136)
- hsa-mir-300 (MIRT528137)
- hsa-mir-5195-5p (MIRT528138)
- hsa-mir-338-5p (MIRT528139)
- hsa-mir-592 (MIRT700662)
- hsa-mir-6796-5p (MIRT700663)
- hsa-mir-6810-5p (MIRT700664)
- hsa-mir-4666b (MIRT700665)
- hsa-mir-597-5p (MIRT700666)
- hsa-mir-6742-5p (MIRT700667)
- hsa-mir-4472 (MIRT700668)
- hsa-mir-4447 (MIRT700669)
- hsa-mir-3151-5p (MIRT700670)
- hsa-mir-491-5p (MIRT700671)
- hsa-mir-4652-5p (MIRT700672)
- hsa-mir-3191-3p (MIRT700673)
- hsa-mir-3144-5p (MIRT700674)
- hsa-mir-1914-5p (MIRT700675)
- hsa-mir-759 (MIRT700676)
- hsa-mir-299-3p (MIRT700677)
- hsa-mir-6874-3p (MIRT700678)
- hsa-mir-148b-5p (MIRT700679)
- hsa-mir-3154 (MIRT700680)
miRNA Products
- Search ViGene Biosciences for PPP1R10
Inhibitory RNA Products
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Clone Products
- VectorBuilder custom plasmid, inducible vectors for PPP1R10
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available PPP1R10 gene related products
- orf clones - Search results for available PPP1R10 gene related products
- Applied Biological Materials Clones for PPP1R10
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
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ViGene Biosciences adenoviral particle packaged cDNA for PPP1R10 gene
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ViGene Biosciences lentiviral particle packaged cDNA for PPP1R10 gene
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No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for PPP1R10 Gene
Localization for PPP1R10 Gene
Subcellular locations from UniProtKB/Swiss-Prot for PPP1R10 Gene
- Nucleus. Note=Found in discrete nucleoplasmic bodies and within nucleoli. Associates with chromatin during interphase, excluded from condensed chromosomes during early mitosis and is reloaded onto chromosomes at the late telophase (By similarity). {ECO:0000250}.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
- Nuclear bodies (4)
- Nucleoplasm (4)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000784 | colocalizes_with nuclear chromosome, telomeric region | IDA | 24270157 |
| GO:0000785 | chromatin | IEA,ISS | -- |
| GO:0005634 | nucleus | TAS | 9461602 |
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0016604 | nuclear body | IDA | -- |
Pathways & Interactions for PPP1R10 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Activation of cAMP-Dependent PKA |
.77
|
.56
|
| 2 | Beta-Adrenergic Signaling |
.36
|
|
| 3 | PI3K / Akt Signaling | ||
| 4 | mTOR Pathway |
.32
|
|
| 5 | GPCR Pathway | ||
Pathways by source for PPP1R10 Gene
1 Tocris pathway for PPP1R10 Gene
14 Qiagen pathways for PPP1R10 Gene
1 Cell Signaling Technology pathway for PPP1R10 Gene
Interacting Proteins for PPP1R10 Gene
Selected Interacting proteins:
ENSP00000365694
Q96QC0-PP1RA_HUMAN
for PPP1R10 Gene via
STRING
UniProtKB
IID
MINT
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006606 | protein import into nucleus | TAS | 9461602 |
| GO:0032515 | negative regulation of phosphoprotein phosphatase activity | IEA | -- |
| GO:0043086 | negative regulation of catalytic activity | IEA | -- |
No data available for SIGNOR curated interactions for PPP1R10 Gene
Transcripts for PPP1R10 Gene
mRNA/cDNA for PPP1R10 Gene
- (4) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (26) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for PPP1R10 Gene
CRISPR Products
-
OriGene CRISPR knockouts for PPP1R10
- genomics-online: gRNA clones - Search results for available PPP1R10 gene related products
- Applied Biological Materials CRISPR for PPP1R10
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for PPP1R10
- GenScript: Design CRISPR guide RNA sequences for PPP1R10
miRNA Products
- Search ViGene Biosciences for PPP1R10
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PPP1R10
- Browse OriGene Inhibitory RNA Products For PPP1R10
- genomics-online: shRNA clones - Search results for available PPP1R10 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for PPP1R10 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for PPP1R10
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PPP1R10
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available PPP1R10 gene related products
- orf clones - Search results for available PPP1R10 gene related products
- Applied Biological Materials Clones for PPP1R10
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for PPP1R10 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Inner Cell Mass (Early Embryonic Tissues)
This gene is overexpressed in Cervix (21.4), Peripheral blood mononuclear cells (11.0), and Breast (9.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for PPP1R10 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of PPP1R10 Gene:
PPP1R10SOURCE GeneReport for Unigene cluster for PPP1R10 Gene:
Hs.106019mRNA Expression by UniProt/SwissProt for PPP1R10 Gene:
Q96QC0-PP1RA_HUMAN
Tissue specificity:
Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Evidence on tissue expression from TISSUES for PPP1R10 Gene
- Nervous system(4.7)
- Liver(4.4)
- Stomach(2.8)
- Kidney(2.3)
- Muscle(2.3)
- Intestine(2)
Primer Products
-
OriGene qPCR primer pairs for PPP1R10
- genomics-online: primer clones - Search results for available PPP1R10 gene related products
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for PPP1R10 Gene
Orthologs for PPP1R10 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | PPP1R10 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | PPP1R10 33 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | PPP1R10 34 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | PPP1R10 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Ppp1r10 33 16 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
OneToMany | |
| -- 34 |
|
OneToMany | |||
| rat (Rattus norvegicus) |
Mammalia | Ppp1r10 33 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | PPP1R10 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | Str.10280 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | ppp1r10 33 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | PNUTS 34 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.8858 34 |
|
OneToMany |
- Species where no ortholog for PPP1R10 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for PPP1R10 Gene
Pseudogenes.org Pseudogenes for PPP1R10 Gene
Variants for PPP1R10 Gene
| SNP ID | Clin | Chr 06 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000157407 | -- | 30,614,454(-) | A/C | intron_variant | |
| rs1000442325 | -- | 30,616,660(-) | C/T | 5_prime_UTR_variant, non_coding_transcript_variant | |
| rs1000473154 | -- | 30,616,508(-) | G/A | 5_prime_UTR_variant, non_coding_transcript_variant | |
| rs1000483702 | -- | 30,608,257(-) | G/A | intron_variant | |
| rs1000549684 | -- | 30,613,169(-) | C/T | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2670269 | CNV | deletion | 23128226 |
| esv2731791 | CNV | deletion | 23290073 |
| esv3411275 | CNV | duplication | 20981092 |
| nsv1074389 | CNV | deletion | 25765185 |
| nsv1122126 | CNV | deletion | 24896259 |
| nsv1144137 | CNV | deletion | 24896259 |
| nsv5244 | CNV | deletion | 18451855 |
| nsv601264 | CNV | loss | 21841781 |
| nsv601481 | CNV | loss | 21841781 |
| nsv830626 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
3.13% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.03;
37.29% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for PPP1R10 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- PPP1R10
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PPP1R10 Gene
Disorders for PPP1R10 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| melanoma, cutaneous malignant 1 |
|
|
Search PPP1R10 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for PPP1R10
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for PPP1R10 Gene
Publications for PPP1R10 Gene
- Cloning of a new gene (FB19) within HLA class I region. (PMID: 9784381) Totaro A … Gasparini P (Biochemical and biophysical research communications 1998) 2 3 4 58
- Purification and characterisation of p99, a nuclear modulator of protein phosphatase 1 activity. (PMID: 9450550) Kreivi JP … Lamond AI (FEBS letters 1997) 3 4 22 58
- PNUTS knockdown potentiates the apoptotic effect of Roscovitine in breast and colon cancer cells. (PMID: 20372802) De Leon G … Krucher NA (International journal of oncology 2010) 3 22 58
- High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PMID: 19851445) Barcellos LF … Criswell LA (PLoS genetics 2009) 3 44 58
- CAT53 and HFE alleles in Alzheimer's disease: a putative protective role of the C282Y HFE mutation. (PMID: 19429178) Correia AP … Porto G (Neuroscience letters 2009) 3 44 58
Products for PPP1R10 Gene
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- Cyagen custom Knockout/knockin (KOKI) mouse models for PPP1R10
- VectorBuilder custom plasmid, inducible vectors for PPP1R10
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PPP1R10
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 29 available PPP1R10 Antibodies ranked by validation data
- Compare Top PPP1R10 Antibodies
- antibodies-online: Search results for available PPP1R10 related products ranked by validation data
- antibodies-online: Search results for 4 available PPP1R10 Proteins ranked by validation data
- Compare Top PPP1R10 Proteins
- Search GeneTex for Antibodies for PPP1R10
- Search GeneTex for Proteins for PPP1R10
- ViGene Biosciences adenoviral particle packaged cDNA for PPP1R10 gene
- ViGene Biosciences lentiviral particle packaged cDNA for PPP1R10 gene
- ViGene Biosciences ready-to-package AAV shRNAs for PPP1R10 gene
- Search ViGene Biosciences for PPP1R10
- Santa Cruz Biotechnology (SCBT) Antibodies for PPP1R10
- Search Santa Cruz Biotechnology (SCBT) for PPP1R10 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for PPP1R10
- genomics-online: cdna clones - Search results for available PPP1R10 gene related products
- orf clones - Search results for available PPP1R10 gene related products
- genomics-online: gRNA clones - Search results for available PPP1R10 gene related products
- genomics-online: primer clones - Search results for available PPP1R10 gene related products
- genomics-online: shRNA clones - Search results for available PPP1R10 gene related products
Sources for PPP1R10 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems