Aliases for PPFIBP2 Gene
External Ids for PPFIBP2 Gene
Previous GeneCards Identifiers for PPFIBP2 Gene
This gene encodes a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. The encoded protein is a beta liprin and plays a role in axon guidance and neuronal synapse development by recruiting LAR protein-tyrosine phosphatases to the plasma membrane. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
GeneCards Summary for PPFIBP2 Gene
PPFIBP2 (PPFIA Binding Protein 2) is a Protein Coding gene. Diseases associated with PPFIBP2 include Bile Duct Cancer and Bile Duct Adenocarcinoma. Among its related pathways are Ectoderm Differentiation. Gene Ontology (GO) annotations related to this gene include integrase activity. An important paralog of this gene is PPFIBP1.
UniProtKB/Swiss-Prot for PPFIBP2 Gene
May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A.