Aliases for PPBPP2 Gene

Aliases for PPBPP2 Gene

  • Pro-Platelet Basic Protein Pseudogene 2 2 3 5
  • Pro-Platelet Basic Protein-Like 2 2 3
  • SPBPBP 2 3
  • DNA-Binding Protein Amplifying Expression Of Surfactant Protein B 3
  • Putative Platelet Basic Protein-Like 2 3
  • DNA-Binding Protein SPBPBP 3
  • PPBPL2 3
  • PPBPP2 5

External Ids for PPBPP2 Gene

Previous HGNC Symbols for PPBPP2 Gene

  • PPBPL2

Previous GeneCards Identifiers for PPBPP2 Gene

  • GC04M074920

Summaries for PPBPP2 Gene

GeneCards Summary for PPBPP2 Gene

PPBPP2 (Pro-Platelet Basic Protein Pseudogene 2) is a Pseudogene. Among its related pathways are PEDF Induced Signaling and Akt Signaling.

Additional gene information for PPBPP2 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for PPBPP2 Gene

Genomics for PPBPP2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for PPBPP2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH04J074054 Promoter/Enhancer 1.9 FANTOM5 Ensembl ENCODE dbSUPER 250.7 -0.9 -928 4.6 NCOR1 IKZF1 JUND ZNF592 ATF2 ZNF10 NFIC CEBPB MBD2 TBP PPBPP2 lnc-CXCL3-2 CXCL8 EREG MTHFD2L CXCL2 CXCL3 ENSG00000250220 ENSG00000288019 HSALNG0035190
GH04J074044 Enhancer 0.7 Ensembl ENCODE 0.4 +11.8 11798 3.2 REST CTCF MAFF RAD21 SMC3 ZNF316 MAFK MAFG ZEB2 CTBP1 MTHFD2L CXCL3 LOC105377275 lnc-MTHFD2L-4 lnc-CXCL3-2 PPBPP2 CXCL2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around PPBPP2 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for PPBPP2 Gene

Latest Assembly
chr4:74,054,038-74,055,399
(GRCh38/hg38)
Size:
1,362 bases
Orientation:
Minus strand

Previous Assembly
chr4:74,919,755-74,921,116
(GRCh37/hg19 by Entrez Gene)
Size:
1,362 bases
Orientation:
Minus strand

chr4:74,919,755-74,921,116
(GRCh37/hg19 by Ensembl)
Size:
1,362 bases
Orientation:
Minus strand

Genomic View for PPBPP2 Gene

Genes around PPBPP2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PPBPP2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PPBPP2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PPBPP2 Gene

Proteins for PPBPP2 Gene

Post-translational modifications for PPBPP2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for PPBPP2 Gene

Domains & Families for PPBPP2 Gene

Suggested Antigen Peptide Sequences for PPBPP2 Gene

GenScript: Design optimal peptide antigens:
  • DNA-binding protein amplifying expression of surfactant protein B (PBPL2_HUMAN)

No data available for Gene Families , Protein Domains , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for PPBPP2 Gene

Function for PPBPP2 Gene

Phenotypes From GWAS Catalog for PPBPP2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PPBPP2 Gene

Localization for PPBPP2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for PPBPP2 Gene

Pathways & Interactions for PPBPP2 Gene

PathCards logo

SuperPathways for PPBPP2 Gene

SuperPathway Contained pathways
1 PEDF Induced Signaling
.94
.94
.73
.71
.62
.61
.47
.46
2 ERK Signaling
.61
.61
.51
3 Akt Signaling
.60
.60
4 PAK Pathway
.56
.56
5 CCR5 Pathway in Macrophages
.33
genes like me logo Genes that share pathways with PPBPP2: view

Pathways by source for PPBPP2 Gene

17 Qiagen pathways for PPBPP2 Gene
  • Akt Signaling
  • all-trans-Retinoic Acid Signaling in Brain
  • Antioxidant Action of Vitamin-C
  • Chemokine Signaling
  • Endothelin-1 Signaling Pathway

Gene Ontology (GO) - Biological Process for PPBPP2 Gene

None

No data available for Interacting Proteins and SIGNOR curated interactions for PPBPP2 Gene

Drugs & Compounds for PPBPP2 Gene

No Compound Related Data Available

Transcripts for PPBPP2 Gene

mRNA/cDNA for PPBPP2 Gene

1 REFSEQ mRNAs :
3 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for PPBPP2 Gene

No ASD Table

Relevant External Links for PPBPP2 Gene

GeneLoc Exon Structure for
PPBPP2

Expression for PPBPP2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for PPBPP2 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for PPBPP2

SOURCE GeneReport for Unigene cluster for PPBPP2 Gene:

Hs.3134
genes like me logo Genes that share expression patterns with PPBPP2: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for PPBPP2 Gene

Orthologs for PPBPP2 Gene

Evolution for PPBPP2 Gene

ENSEMBL:
Gene Tree for PPBPP2 (if available)
TreeFam:
Gene Tree for PPBPP2 (if available)
Alliance of Genome Resources:
Additional Orthologs for PPBPP2

No data available for Orthologs for PPBPP2 Gene

Paralogs for PPBPP2 Gene

No data available for Paralogs for PPBPP2 Gene

Variants for PPBPP2 Gene

Structural Variations from Database of Genomic Variants (DGV) for PPBPP2 Gene

Variant ID Type Subtype PubMed ID
esv3575747 CNV gain 25503493
nsv1004768 CNV gain 25217958
nsv1006029 CNV gain 25217958
nsv525980 CNV gain 19592680

Additional Variant Information for PPBPP2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
PPBPP2
Leiden Open Variation Database (LOVD)
PPBPP2

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , dbSNP identifiers (rs#s) for variants without ClinVar clinical significance and Variation tolerance for PPBPP2 Gene

Disorders for PPBPP2 Gene

Additional Disease Information for PPBPP2

No disorders were found for PPBPP2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PPBPP2 Gene

Publications for PPBPP2 Gene

  1. DNA binding proteins that amplify surfactant protein B gene expression: isolation and characterization. (PMID: 7887923) Luzi P … Strayer DS (Biochemical and biophysical research communications 1995) 2 3
  2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier LW … Wilson RK (Nature 2005) 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3

Products for PPBPP2 Gene

Sources for PPBPP2 Gene