POU5F1P4 Gene (Pseudogene)

POU Class 5 Homeobox 1 Pseudogene 4

GC01P155444
GIFtS:
16
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Aliases for POU5F1P4 Gene

Aliases for POU5F1P4 Gene

  • POU Class 5 Homeobox 1 Pseudogene 4 2 3 5
  • POU Domain Class 5, Transcription Factor 1 Pseudogene 4 2 3
  • POU Domain Transcription Factor OCT4-Pg4 3 13
  • Oct4-Pg4 2 3
  • POU5FLC1 2 3
  • POU Domain, Class 5, Transcription Factor 1 3
  • Octamer-Binding Transcription Factor 3 3
  • Octamer-Binding Protein 3 3
  • Octamer-Binding Protein 4 3
  • POU Domain Protein 13
  • POU5F1P4 5
  • POU5F1 3
  • OTF-3 3
  • Oct-3 3
  • Oct-4 3
  • OCT3 3
  • OCT4 3
  • OTF3 3

External Ids for POU5F1P4 Gene

Previous GeneCards Identifiers for POU5F1P4 Gene

  • GC00U922238
  • GC01P153670
  • GC01P155403
  • GC01P126764
  • GC01P155436
  • GC01P155437
  • GC01P155447
  • GC01P155448
  • GC01P155446
  • GC01P155445
  • GC01P155438
  • GC01P155439
  • GC01P155441
  • GC01P155442
  • GC01P155443

Summaries for POU5F1P4 Gene

GeneCards Summary for POU5F1P4 Gene

POU5F1P4 (POU Class 5 Homeobox 1 Pseudogene 4) is a Pseudogene. Diseases associated with POU5F1P4 include Colorectal Cancer.

Additional gene information for POU5F1P4 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for POU5F1P4 Gene

Genomics for POU5F1P4 Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for POU5F1P4 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH01J155433 Enhancer 0.2 Ensembl 600.7 +0.2 223 0.4 POU5F1P4 piR-41318-001 MIR555 ASH1L RUSC1-AS1 RUSC1
GH01J155123 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 5.8 -302.1 -302136 14.7 CEBPG SP1 HNRNPL CREB1 GATAD2A ATF7 TEAD4 PRDM10 ZNF629 REST EFNA1 SLC50A1 MG604298 CLK2 GON4L KHDC4 UBAP2L ENSG00000271267 MSTO1 RUSC1-AS1
GH01J155172 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 4.3 -257.8 -257777 7.2 SP1 HNRNPL CREB1 GATAD2A CTCF ZBTB33 PRDM10 ZNF629 RFX1 NFKBIZ KRTCAP2 TRIM46 CLK2 KHDC4 GON4L ENSG00000271267 GBAP1 RUSC1-AS1 SHC1 THBS3
GH01J155206 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 4.3 -224.0 -224008 5.5 HNRNPL GATAD2A CTCF PRDM10 ZNF629 RFX1 LEF1 ZNF692 NFRKB POLR2A THBS3 MTX1 TRIM46 KRTCAP2 FAM189B SCAMP3 LMNA DAP3 FDPS POU5F1P4
GH01J155069 Enhancer 1.3 ENCODE CraniofacialAtlas dbSUPER 4.6 -362.6 -362562 2.4 CTCF PRDM10 ZNF512 RFX1 LEF1 ZNF692 JUND PRDM1 ZIC2 RBFOX2 ADAM15 GBAP1 THBS3 POU5F1P4 HSALNG0007466 DCST1-AS1 ENSG00000251246 EFNA3 EFNA4
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around POU5F1P4 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for POU5F1P4 Gene

Genomic Locations for POU5F1P4 Gene
chr1:155,433,178-155,434,262
(GRCh38/hg38)
Size:
1,085 bases
Orientation:
Plus strand
chr1:155,402,969-155,404,053
(GRCh37/hg19)
Size:
1,085 bases
Orientation:
Plus strand

Genomic View for POU5F1P4 Gene

Genes around POU5F1P4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
POU5F1P4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for POU5F1P4 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for POU5F1P4 Gene

Proteins for POU5F1P4 Gene

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  • Protein details for POU5F1P4 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    E9LRA1-E9LRA1_HUMAN
    Recommended name:
    POU domain protein
    Protein Accession:
    E9LRA1

    Protein attributes for POU5F1P4 Gene

    Size:
    286 amino acids
    Molecular mass:
    31284 Da
    Quaternary structure:
    No Data Available

neXtProt entry for POU5F1P4 Gene

Post-translational modifications for POU5F1P4 Gene

No Post-translational modifications

No data available for DME Specific Peptides for POU5F1P4 Gene

Domains & Families for POU5F1P4 Gene

Gene Families for POU5F1P4 Gene

Unknown:
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
  • Belongs to the POU transcription factor family.
HGNC:

Protein Domains for POU5F1P4 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for POU5F1P4 Gene

GenScript: Design optimal peptide antigens:
  • POU domain transcription factor OCT4-pg4 (D5K9S3_HUMAN)
  • POU domain transcription factor OCT4-pg1 (D5K9S4_HUMAN)
  • POU domain transcription factor OCT4-pg4 (D5K9S5_HUMAN)
  • POU domain transcription factor OCT4-pg4 (D5K9S8_HUMAN)
  • POU domain transcription factor OCT4-pg4 (D5K9T7_HUMAN)
genes like me logo Genes that share domains with POU5F1P4: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for POU5F1P4 Gene

Function for POU5F1P4 Gene

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  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
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  6. Cell Line

Phenotypes From GWAS Catalog for POU5F1P4 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for POU5F1P4 Gene

Localization for POU5F1P4 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for POU5F1P4 Gene

Pathways & Interactions for POU5F1P4 Gene

PathCards logo

SuperPathways for POU5F1P4 Gene

No Data Available

Gene Ontology (GO) - Biological Process for POU5F1P4 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for POU5F1P4 Gene

Drugs & Compounds for POU5F1P4 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for POU5F1P4 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for POU5F1P4 Gene

167 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for POU5F1P4 Gene

No ASD Table

Relevant External Links for POU5F1P4 Gene

GeneLoc Exon Structure for
POU5F1P4

Expression for POU5F1P4 Gene

Products:

  1. Primer
  2. Gene Expression Assay

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for POU5F1P4 Gene

mRNA expression in normal human tissues for POU5F1P4 Gene
mRNA expression by BioGPS for POU5F1P4 GenemRNA expression by GTEx for POU5F1P4 Gene

mRNA differential expression in normal tissues according to GTEx for POU5F1P4 Gene

This gene is overexpressed in Kidney - Cortex (x6.4).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for POU5F1P4

SOURCE GeneReport for Unigene cluster for POU5F1P4 Gene:

Hs.632482
genes like me logo Genes that share expression patterns with POU5F1P4: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for POU5F1P4 Gene

Orthologs for POU5F1P4 Gene

Evolution for POU5F1P4 Gene

ENSEMBL:
Gene Tree for POU5F1P4 (if available)
TreeFam:
Gene Tree for POU5F1P4 (if available)

No data available for Orthologs for POU5F1P4 Gene

Paralogs for POU5F1P4 Gene

(18) SIMAP similar genes for POU5F1P4 Gene using alignment to 35 proteins:

  • D5K9S3_HUMAN
  • D5K9S4_HUMAN
  • D5K9S5_HUMAN
  • D5K9S8_HUMAN
  • D5K9T7_HUMAN
  • D5K9T8_HUMAN
  • D5K9T9_HUMAN
  • D5K9U0_HUMAN
  • D5K9U2_HUMAN
  • D5K9U4_HUMAN
  • D5K9U9_HUMAN
  • D5K9V1_HUMAN
  • D5K9W5_HUMAN
  • D5K9W6_HUMAN
  • E9LR91_HUMAN
  • E9LR92_HUMAN
  • E9LR93_HUMAN
  • E9LR96_HUMAN
  • E9LRA1_HUMAN
  • E9LRF2_HUMAN
  • E9LRF5_HUMAN
  • E9LRF8_HUMAN
  • E9LRJ2_HUMAN
  • E9LRM0_HUMAN
  • E9LRM1_HUMAN
  • E9LRM2_HUMAN
  • E9LRM3_HUMAN
  • E9LRP2_HUMAN
  • E9LRP3_HUMAN
  • E9LRP4_HUMAN
  • E9LRP6_HUMAN
  • E9LRR8_HUMAN
  • E9LRS9_HUMAN
  • E9LRT0_HUMAN
  • E9LRT1_HUMAN
genes like me logo Genes that share paralogs with POU5F1P4: view

No data available for Paralogs for POU5F1P4 Gene

Variants for POU5F1P4 Gene

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  1. SNP Genotyping and Copy Number Assay

Structural Variations from Database of Genomic Variants (DGV) for POU5F1P4 Gene

Variant ID Type Subtype PubMed ID
esv33869 CNV loss 17666407
nsv831636 CNV loss 17160897
nsv946415 CNV duplication 23825009

Additional Variant Information for POU5F1P4 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
POU5F1P4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) and Variation tolerance for POU5F1P4 Gene

Disorders for POU5F1P4 Gene

MalaCards: The human disease database

(1) MalaCards diseases for POU5F1P4 Gene - From: LncRNADisease

Disorder Aliases PubMed IDs
colorectal cancer
  • crc
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for POU5F1P4

ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with POU5F1P4: view

No data available for UniProtKB/Swiss-Prot and Genatlas for POU5F1P4 Gene

Publications for POU5F1P4 Gene

  1. Expression and differentiation between OCT4A and its Pseudogenes in human ESCs and differentiated adult somatic cells. (PMID: 24586860) Jez M … Dominko T (PloS one 2014) 3
  2. Pseudogene OCT4-pg4 functions as a natural micro RNA sponge to regulate OCT4 expression by competing for miR-145 in hepatocellular carcinoma. (PMID: 23615404) Wang L … Yang AG (Carcinogenesis 2013) 3
  3. Differential expression of Oct4 variants and pseudogenes in normal urothelium and urothelial cancer. (PMID: 23933063) Wezel F … Southgate J (The American journal of pathology 2013) 3
  4. Transcriptional regulation of Oct4 by a long non-coding RNA antisense to Oct4-pseudogene 5. (PMID: 21151833) Hawkins PG … Morris KV (Transcription 2010) 3
  5. Oct4 and its pseudogenes confuse stem cell research. (PMID: 18371374) Liedtke S … Kögler G (Cell stem cell 2007) 3

ExternalLinks

View latest publications for POU5F1P4 gene in Mastermind

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