Aliases for POU3F4 Gene
External Ids for POU3F4 Gene
Previous HGNC Symbols for POU3F4 Gene
Previous GeneCards Identifiers for POU3F4 Gene
This gene encodes a member of the POU-III class of neural transcription factors. This family member plays a role in inner ear development. The protein is thought to be involved in the mediation of epigenetic signals which induce striatal neuron-precursor differentiation. Mutations in this gene are associated with X chromosome-linked nonsyndromic mixed deafness. [provided by RefSeq, Dec 2012]
GeneCards Summary for POU3F4 Gene
POU3F4 (POU Class 3 Homeobox 4) is a Protein Coding gene. Diseases associated with POU3F4 include Deafness, X-Linked 2 and Developmental Delay-Deafness Syndrome, Hildebrand Type. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and double-stranded DNA binding. An important paralog of this gene is POU3F3.
UniProtKB/Swiss-Prot for POU3F4 Gene
Probable transcription factor which exert its primary action widely during early neural development and in a very limited set of neurons in the mature brain.