Aliases for POU3F3 Gene
External Ids for POU3F3 Gene
Previous GeneCards Identifiers for POU3F3 Gene
This gene encodes a POU-domain containing protein that functions as a transcription factor. The encoded protein recognizes an octamer sequence in the DNA of target genes. This protein may play a role in development of the nervous system. [provided by RefSeq, Apr 2015]
GeneCards Summary for POU3F3 Gene
POU3F3 (POU Class 3 Homeobox 3) is a Protein Coding gene. Diseases associated with POU3F3 include Central Nervous System Tuberculosis and Agraphia. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and HMG box domain binding. An important paralog of this gene is POU3F2.
UniProtKB/Swiss-Prot for POU3F3 Gene
Transcription factor that acts synergistically with SOX11 and SOX4. Plays a role in neuronal development. Is implicated in an enhancer activity at the embryonic met-mesencephalic junction; the enhancer element contains the octamer motif (5-ATTTGCAT-3) (By similarity).