Aliases for POTEG Gene

Aliases for POTEG Gene

  • POTE Ankyrin Domain Family Member G 2 3 4 5
  • POTE-14 2 3 4
  • POTE14 2 3 4
  • Prostate, Ovary, Testis-Expressed Protein On Chromosome 14 3 4
  • Cancer/Testis Antigen Family 104, Member 4 2 3
  • ANKRD26-Like Family C Member 2 3 4
  • POTE14alpha 2 3
  • CT104.4 2 3
  • A26C2 3 4
  • Protein Expressed In Prostate, Ovary, Testis, And Placenta 14 3
  • POTE Ankyrin Domain Family, Member G 2
  • ANKRD26-Like Family C, Member 2 2
  • ACTBL1 3
  • POTE22 3
  • POTEG 5

External Ids for POTEG Gene

Previous HGNC Symbols for POTEG Gene

  • A26C2

Previous GeneCards Identifiers for POTEG Gene

  • GC14P018628
  • GC14P019554

Summaries for POTEG Gene

GeneCards Summary for POTEG Gene

POTEG (POTE Ankyrin Domain Family Member G) is a Protein Coding gene. An important paralog of this gene is POTEM.

Additional gene information for POTEG Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for POTEG Gene

Genomics for POTEG Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for POTEG Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14J019511 Promoter 0.5 Ensembl 0.2 -76.9 -76860 0.4 ZBTB48 ZBTB17 ENSG00000274649 piR-48209-169 ENSG00000273639 POTEG OR11H2
GH14J019335 Promoter 0.3 Ensembl 0.2 +97.3 97341 2.8 DUXAP10 ENSG00000244306 piR-47211-164 piR-57600-002 NONHSAG014339.2 LINC01297-DUXAP10-NBEAP6 POTEG POTEM
GH14J019349 Enhancer 0.2 Ensembl 0.2 +84.7 84740 0.4 piR-52457-003 piR-48287-002 NONHSAG014339.2 LOC105378174 LINC01297 LINC01297-DUXAP10-NBEAP6 POTEG POTEM
GH14J019688 Promoter 0.3 Ensembl 0.1 -254.1 -254060 0.4 ARHGAP42P4 lnc-OR4N2-6 ENSG00000257142 OR11H2 POTEG
GH14J019304 Enhancer 0.2 Ensembl 0.1 +129.4 129441 0.2 piR-54859-002 BMS1P17 lnc-POTEG-7-002 DUXAP10 ENSG00000244306 NONHSAG014339.2 LINC01297-DUXAP10-NBEAP6 POTEG POTEM
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around POTEG on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for POTEG

Top Transcription factor binding sites by QIAGEN in the POTEG gene promoter:
  • ATF-2
  • Nkx2-2
  • Olf-1
  • POU3F2
  • POU3F2 (N-Oct-5a)
  • POU3F2 (N-Oct-5b)
  • PPAR-gamma1
  • PPAR-gamma2

Genomic Locations for POTEG Gene

Genomic Locations for POTEG Gene
31,856 bases
Minus strand
36,714 bases
Plus strand

Genomic View for POTEG Gene

Genes around POTEG on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
POTEG Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for POTEG Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for POTEG Gene

Proteins for POTEG Gene

  • Protein details for POTEG Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    POTE ankyrin domain family member G
    Protein Accession:
    Secondary Accessions:
    • A1L153
    • A6NMI9
    • Q6S5H6
    • Q6S8J2

    Protein attributes for POTEG Gene

    508 amino acids
    Molecular mass:
    57096 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAS58870.1; Type=Frameshift; Evidence={ECO:0000305};
    • [Isoform 2]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
    • [Isoform 1]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.

    Alternative splice isoforms for POTEG Gene


neXtProt entry for POTEG Gene

Post-translational modifications for POTEG Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for POTEG Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for POTEG Gene

Domains & Families for POTEG Gene

Gene Families for POTEG Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for POTEG Gene

  • Ankyrin repeat signature

Suggested Antigen Peptide Sequences for POTEG Gene

GenScript: Design optimal peptide antigens:
  • Prostate, ovary, testis-expressed protein on chromosome 14 (POTEG_HUMAN)

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the POTE family.
  • Belongs to the POTE family.
genes like me logo Genes that share domains with POTEG: view

Function for POTEG Gene

Gene Ontology (GO) - Molecular Function for POTEG Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IEA --
genes like me logo Genes that share ontologies with POTEG: view
genes like me logo Genes that share phenotypes with POTEG: view

Animal Model Products

CRISPR Products

miRNA for POTEG Gene

miRTarBase miRNAs that target POTEG

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for POTEG

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for POTEG Gene

Localization for POTEG Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for POTEG Gene

Pathways & Interactions for POTEG Gene

PathCards logo

SuperPathways for POTEG Gene

No Data Available

Gene Ontology (GO) - Biological Process for POTEG Gene


No data available for Pathways by source and SIGNOR curated interactions for POTEG Gene

Drugs & Compounds for POTEG Gene

No Compound Related Data Available

Transcripts for POTEG Gene

mRNA/cDNA for POTEG Gene

5 NCBI additional mRNA sequence :
3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for POTEG

Alternative Splicing Database (ASD) splice patterns (SP) for POTEG Gene

No ASD Table

Relevant External Links for POTEG Gene

GeneLoc Exon Structure for

Expression for POTEG Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for POTEG Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for POTEG Gene

This gene is overexpressed in Prostate (x30.6) and Testis (x20.6).

Protein differential expression in normal tissues from HIPED for POTEG Gene

This gene is overexpressed in Brain (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for POTEG Gene

Protein tissue co-expression partners for POTEG Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for POTEG

SOURCE GeneReport for Unigene cluster for POTEG Gene:


Evidence on tissue expression from TISSUES for POTEG Gene

  • Lung(2.9)
  • Nervous system(2.4)
genes like me logo Genes that share expression patterns with POTEG: view

No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for POTEG Gene

Orthologs for POTEG Gene

This gene was present in the common ancestor of chordates.

Orthologs for POTEG Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 31
  • 84 (a)
-- 31
  • 80 (a)
(Canis familiaris)
Mammalia -- 31
  • 42 (a)
-- 31
  • 38 (a)
-- 31
  • 36 (a)
-- 31
  • 11 (a)
-- 31
  • 7 (a)
-- 31
  • 6 (a)
-- 31
  • 2 (a)
-- 31
(Mus musculus)
Mammalia Gm1758 31
  • 33 (a)
(Ornithorhynchus anatinus)
Mammalia -- 31
  • 4 (a)
(Bos Taurus)
Mammalia -- 31
(Gallus gallus)
Aves -- 31
  • 8 (a)
(Anolis carolinensis)
Reptilia -- 31
  • 36 (a)
(Danio rerio)
Actinopterygii ANKRD7 31
  • 5 (a)
Species where no ortholog for POTEG was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for POTEG Gene

Gene Tree for POTEG (if available)
Gene Tree for POTEG (if available)
Evolutionary constrained regions (ECRs) for POTEG: view image

Paralogs for POTEG Gene

genes like me logo Genes that share paralogs with POTEG: view

Variants for POTEG Gene

Additional dbSNP identifiers (rs#s) for POTEG Gene

Structural Variations from Database of Genomic Variants (DGV) for POTEG Gene

Variant ID Type Subtype PubMed ID
dgv1182e59 CNV duplication 20981092
dgv1183e59 CNV duplication 20981092
dgv1184e59 CNV duplication 20981092
dgv1185e59 CNV duplication 20981092
dgv1186e59 CNV duplication 20981092
dgv1752n100 CNV gain 25217958
dgv1753n100 CNV gain 25217958
dgv1756n100 CNV loss 25217958
dgv1757n100 CNV gain 25217958
dgv1759n100 CNV gain 25217958
dgv1760n100 CNV gain+loss 25217958
dgv1761n100 CNV gain+loss 25217958
dgv1762n100 CNV loss 25217958
dgv1763n100 CNV gain 25217958
dgv1764n100 CNV loss 25217958
dgv1765n100 CNV gain+loss 25217958
dgv1766n100 CNV gain 25217958
dgv1767n100 CNV loss 25217958
dgv1768n100 CNV gain 25217958
dgv1769n100 CNV gain 25217958
dgv1770n100 CNV gain+loss 25217958
dgv1771n100 CNV loss 25217958
dgv1772n100 CNV gain 25217958
dgv33e203 CNV gain+loss 21179565
dgv3489n54 CNV gain 21841781
dgv3494n54 CNV loss 21841781
dgv3512n54 CNV loss 21841781
dgv3513n54 CNV loss 21841781
dgv3514n54 CNV loss 21841781
dgv3515n54 CNV loss 21841781
dgv45e180 CNV loss 20482838
dgv86n111 CNV duplication 26073780
esv1005804 OTHER inversion 20482838
esv23873 CNV gain+loss 19812545
esv2748433 CNV deletion 23290073
esv2759971 CNV gain+loss 17122850
esv3329783 CNV duplication 20981092
esv33527 CNV gain+loss 17666407
esv3362070 CNV duplication 20981092
esv3366979 CNV duplication 20981092
esv3377586 CNV duplication 20981092
esv3381124 CNV duplication 20981092
esv3584743 CNV gain 24956385
esv3892461 CNV gain 25118596
esv3892464 CNV gain 25118596
nsv1037353 CNV gain 25217958
nsv1044659 CNV gain 25217958
nsv1048150 CNV gain+loss 25217958
nsv1048393 CNV gain+loss 25217958
nsv1070209 CNV deletion 25765185
nsv1075456 CNV duplication 25765185
nsv1076406 CNV duplication 25765185
nsv1076407 CNV duplication 25765185
nsv1110233 CNV duplication 24896259
nsv1110234 CNV duplication 24896259
nsv1110856 OTHER inversion 24896259
nsv1118532 CNV duplication 24896259
nsv1141242 CNV duplication 24896259
nsv1141243 CNV duplication 24896259
nsv1147454 CNV duplication 26484159
nsv1150196 CNV duplication 26484159
nsv1160152 CNV duplication 26073780
nsv1160154 CNV duplication 26073780
nsv428292 CNV gain+loss 18775914
nsv433422 CNV gain 18776910
nsv436829 CNV insertion 17901297
nsv509526 CNV insertion 20534489
nsv563705 CNV loss 21841781
nsv563729 CNV loss 21841781
nsv7248 OTHER inversion 18451855
nsv819711 CNV loss 19587683
nsv832732 CNV loss 17160897
nsv9117 CNV gain+loss 18304495
nsv951957 CNV duplication 24416366
nsv974303 CNV duplication 23825009
nsv983886 CNV duplication 23825009

Variation tolerance for POTEG Gene

Gene Damage Index Score: 8.49; 85.83% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for POTEG Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for POTEG Gene

Disorders for POTEG Gene

No disorders were found for POTEG Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for POTEG Gene

Publications for POTEG Gene

  1. Five POTE paralogs and their splice variants are expressed in human prostate and encode proteins of different lengths. (PMID: 15276201) Bera TK … Pastan I (Gene 2004) 3 4
  2. Identification of a novel actin isoform in hepatocellular carcinoma. (PMID: 16824795) Chang KW … Yeh CT (Hepatology research : the official journal of the Japan Society of Hepatology 2006) 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4
  4. The DNA sequence and analysis of human chromosome 14. (PMID: 12508121) Heilig R … Weissenbach J (Nature 2003) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3

Products for POTEG Gene

Sources for POTEG Gene