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Aliases for POTEB Gene

Aliases for POTEB Gene

  • POTE Ankyrin Domain Family Member B 2 3 5
  • Prostate, Ovary, Testis-Expressed Protein On Chromosome 15 3 4
  • Cancer/Testis Antigen Family 104, Member 5 2 3
  • ANKRD26-Like Family B, Member 1 2 3
  • POTE-15 3 4
  • POTE15 3 4
  • A26B1 3 4
  • Protein Expressed In Prostate, Ovary, Testis, And Placenta 15 3
  • LOW QUALITY PROTEIN: POTE Ankyrin Domain Family Member B 3
  • POTE Ankyrin Domain Family Member B-Like 3
  • POTE Ankyrin Domain Family, Member B 2
  • ANKRD26-Like Family B Member 1 4
  • CT104.5 3

External Ids for POTEB Gene

Previous HGNC Symbols for POTEB Gene

  • A26B1

Previous GeneCards Identifiers for POTEB Gene

  • GC15M019307
  • GC15M022051

Summaries for POTEB Gene

GeneCards Summary for POTEB Gene

POTEB (POTE Ankyrin Domain Family Member B) is a Protein Coding gene. An important paralog of this gene is POTEB2.

Additional gene information for POTEB Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for POTEB Gene

Genomics for POTEB Gene

Genomic Locations for POTEB Gene

Genomic Locations for POTEB Gene
31,375 bases
Minus strand

Genomic View for POTEB Gene

Genes around POTEB on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
POTEB Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for POTEB Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for POTEB Gene

No data available for GeneHancer (GH) Regulatory Elements for POTEB Gene

Proteins for POTEB Gene

  • Protein details for POTEB Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    POTE ankyrin domain family member B
    Protein Accession:
    Secondary Accessions:
    • Q6NXN7
    • Q6S5H7

    Protein attributes for POTEB Gene

    581 amino acids
    Molecular mass:
    65710 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for POTEB Gene


neXtProt entry for POTEB Gene

Post-translational modifications for POTEB Gene

No Post-translational modifications

Other Protein References for POTEB Gene

No data available for DME Specific Peptides for POTEB Gene

Domains & Families for POTEB Gene

Gene Families for POTEB Gene

Protein Domains for POTEB Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the POTE family.
  • Belongs to the POTE family.
genes like me logo Genes that share domains with POTEB: view

Function for POTEB Gene

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for POTEB Gene

Localization for POTEB Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for POTEB Gene

Pathways & Interactions for POTEB Gene

SuperPathways for POTEB Gene

No Data Available

Gene Ontology (GO) - Biological Process for POTEB Gene


No data available for Pathways by source and SIGNOR curated interactions for POTEB Gene

Drugs & Compounds for POTEB Gene

No Compound Related Data Available

Transcripts for POTEB Gene

mRNA/cDNA for POTEB Gene

(5) REFSEQ mRNAs :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for POTEB Gene

No ASD Table

Relevant External Links for POTEB Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for POTEB Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for POTEB Gene

mRNA differential expression in normal tissues according to GTEx for POTEB Gene

This gene is overexpressed in Testis (x53.0).

Protein differential expression in normal tissues from HIPED for POTEB Gene

This gene is overexpressed in Brain (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for POTEB Gene

Protein tissue co-expression partners for POTEB Gene

NURSA nuclear receptor signaling pathways regulating expression of POTEB Gene:

genes like me logo Genes that share expression patterns with POTEB: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for POTEB Gene

Orthologs for POTEB Gene

This gene was present in the common ancestor of chordates.

Orthologs for POTEB Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 34
  • 89 (a)
(Canis familiaris)
Mammalia -- 34
  • 43 (a)
-- 34
  • 38 (a)
-- 34
  • 38 (a)
-- 34
  • 12 (a)
-- 34
  • 9 (a)
-- 34
  • 7 (a)
-- 34
  • 6 (a)
-- 34
  • 5 (a)
(Mus musculus)
Mammalia Gm1758 34
  • 35 (a)
(Bos Taurus)
Mammalia -- 34
  • 6 (a)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 6 (a)
(Gallus gallus)
Aves -- 34
  • 11 (a)
(Anolis carolinensis)
Reptilia -- 34
  • 37 (a)
(Danio rerio)
Actinopterygii ANKRD7 34
  • 6 (a)
Species where no ortholog for POTEB was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for POTEB Gene

Gene Tree for POTEB (if available)
Gene Tree for POTEB (if available)

Paralogs for POTEB Gene

Variants for POTEB Gene

Sequence variations from dbSNP and Humsavar for POTEB Gene

SNP ID Clin Chr 15 pos Variation AA Info Type
rs1000351633 -- 21,873,451(-) T/C intron_variant
rs1002625923 -- 21,851,470(-) A/G genic_downstream_transcript_variant, intron_variant
rs1002742100 -- 21,854,416(-) G/A genic_downstream_transcript_variant, intron_variant
rs1003637775 -- 21,864,882(-) C/T intron_variant
rs1003731118 -- 21,868,998(-) T/C intron_variant

Structural Variations from Database of Genomic Variants (DGV) for POTEB Gene

Variant ID Type Subtype PubMed ID
dgv2188n100 CNV loss 25217958
dgv2189n100 CNV gain+loss 25217958
dgv2190n100 CNV gain+loss 25217958
dgv2191n100 CNV gain+loss 25217958
dgv2192n100 CNV loss 25217958
dgv2193n100 CNV gain+loss 25217958
dgv2210n100 CNV gain 25217958
dgv2211n100 CNV loss 25217958
dgv2212n100 CNV gain 25217958
dgv2213n100 CNV loss 25217958
dgv2214n100 CNV gain 25217958
dgv2222n100 CNV gain+loss 25217958
dgv2232n100 CNV loss 25217958
dgv2237n100 CNV gain 25217958
dgv2238n100 CNV gain 25217958
nsv428296 CNV gain+loss 18775914
nsv433281 CNV loss 18776910
nsv433282 CNV loss 18776910
nsv436198 CNV deletion 17901297
nsv469642 CNV gain 16826518
nsv471373 CNV gain 19718026
nsv471537 CNV gain 19718026
nsv471675 CNV gain+loss 15918152
nsv475421 CNV novel sequence insertion 20440878
nsv511040 OTHER inversion 20534489
nsv514765 CNV gain 21397061
nsv567312 CNV gain 21841781
nsv567597 CNV loss 21841781
nsv567598 CNV gain 21841781
nsv567604 CNV loss 21841781
nsv7260 OTHER inversion 18451855
nsv817667 CNV gain 17921354
nsv819612 CNV gain 19587683
nsv819770 CNV gain 19587683
nsv821678 CNV loss 15273396
nsv827221 CNV gain 20364138
nsv832915 CNV gain+loss 17160897
nsv832916 CNV gain+loss 17160897
nsv9179 CNV gain+loss 18304495
nsv952318 CNV duplication 24416366
nsv1160227 CNV duplication 26073780
nsv1160218 CNV duplication 26073780
nsv1152117 CNV duplication 26484159
nsv1148204 CNV duplication 26484159
nsv1145973 CNV duplication 26484159
nsv1145855 CNV duplication 26484159
nsv1132396 CNV duplication 24896259
nsv1131081 CNV deletion 24896259
nsv1121887 CNV deletion 24896259
nsv1077793 CNV duplication 25765185
nsv1055063 CNV gain+loss 25217958
nsv1044952 CNV loss 25217958
nsv1043213 CNV gain+loss 25217958
nsv1041388 CNV gain+loss 25217958
esv988919 CNV loss 20482838
esv3892629 CNV loss 25118596
esv3892612 CNV gain 25118596
esv3892609 CNV gain 25118596
esv3892607 CNV gain 25118596
esv3892595 CNV gain+loss 25118596
esv3584865 CNV gain 24956385
esv3584854 CNV gain 24956385
esv3584832 CNV gain 24956385
esv3584810 CNV gain 24956385
esv3584679 CNV loss 24956385
esv33051 CNV gain+loss 17666407
esv29956 CNV loss 18421352
esv2751492 CNV gain 17911159
esv2751488 CNV loss 17911159
esv21579 CNV gain+loss 19812545
esv1004259 OTHER inversion 20482838
dgv96e55 CNV loss 17911159
dgv95e55 CNV loss 17911159
dgv93e55 CNV gain 17911159
dgv92e55 CNV gain 17911159
dgv91e55 CNV gain 17911159
dgv43n16 CNV insertion 17901297
dgv4244n54 CNV loss 21841781
dgv4240n54 CNV loss 21841781
dgv4239n54 CNV loss 21841781
dgv4238n54 CNV gain 21841781
dgv4237n54 CNV loss 21841781
dgv4236n54 CNV loss 21841781
dgv4235n54 CNV loss 21841781
dgv4234n54 CNV loss 21841781
dgv4233n54 CNV gain 21841781
dgv4232n54 CNV gain 21841781
dgv4231n54 CNV gain 21841781
dgv4230n54 CNV loss 21841781
dgv4226n54 CNV loss 21841781
dgv4225n54 CNV loss 21841781
dgv4224n54 CNV loss 21841781
dgv4223n54 CNV gain+loss 21841781
dgv4222n54 CNV gain 21841781
dgv4221n54 CNV loss 21841781
dgv4220n54 CNV gain+loss 21841781
dgv4217n54 CNV loss 21841781
dgv4213n54 CNV loss 21841781
dgv4211n54 CNV gain 21841781
dgv4210n54 CNV gain 21841781
dgv418n67 CNV gain 20364138
dgv4183n54 CNV loss 21841781
dgv4182n54 CNV loss 21841781
dgv4180n54 CNV gain 21841781
dgv4166n54 CNV gain 21841781
dgv4164n54 CNV loss 21841781
dgv4162n54 CNV loss 21841781
dgv2368n100 CNV loss 25217958
dgv2367n100 CNV gain 25217958
dgv2365n100 CNV gain+loss 25217958
dgv2364n100 CNV gain 25217958
dgv2363n100 CNV loss 25217958
dgv2357n100 CNV gain+loss 25217958
dgv2355n100 CNV gain 25217958
dgv2347n100 CNV loss 25217958
dgv2344n100 CNV loss 25217958
dgv2343n100 CNV gain+loss 25217958
dgv2342n100 CNV loss 25217958
dgv2341n100 CNV gain 25217958
dgv2340n100 CNV gain+loss 25217958
dgv2339n100 CNV gain+loss 25217958
dgv2337n100 CNV loss 25217958
dgv2336n100 CNV loss 25217958
dgv2335n100 CNV loss 25217958
dgv2334n100 CNV gain 25217958
dgv2333n100 CNV loss 25217958
dgv2332n100 CNV gain 25217958
dgv2331n100 CNV gain+loss 25217958
dgv2330n100 CNV loss 25217958
dgv2329n100 CNV loss 25217958
dgv2328n100 CNV gain 25217958
dgv2327n100 CNV gain 25217958
dgv2326n100 CNV gain 25217958
dgv2325n100 CNV gain+loss 25217958
dgv2324n100 CNV gain 25217958
dgv2323n100 CNV loss 25217958
dgv2322n100 CNV loss 25217958
dgv2321n100 CNV gain+loss 25217958
dgv2320n100 CNV loss 25217958
dgv2319n100 CNV loss 25217958
dgv2317n100 CNV gain 25217958
dgv2315n100 CNV gain 25217958
dgv2314n100 CNV loss 25217958
dgv2313n100 CNV loss 25217958
dgv2312n100 CNV gain 25217958
dgv2311n100 CNV loss 25217958
dgv2310n100 CNV gain 25217958
dgv2309n100 CNV gain 25217958
dgv2308n100 CNV loss 25217958
dgv2304n100 CNV gain 25217958
dgv2301n100 CNV loss 25217958
dgv2300n100 CNV loss 25217958
dgv2298n100 CNV gain+loss 25217958
dgv2297n100 CNV gain 25217958
dgv2296n100 CNV loss 25217958
dgv2295n100 CNV loss 25217958
dgv2293n100 CNV loss 25217958
dgv2290n100 CNV gain+loss 25217958
dgv2288n100 CNV gain 25217958
dgv2287n100 CNV gain+loss 25217958
dgv2284n100 CNV gain 25217958
dgv2283n100 CNV gain 25217958
dgv2282n100 CNV gain 25217958
dgv2281n100 CNV gain+loss 25217958
dgv2280n100 CNV loss 25217958
dgv2279n100 CNV loss 25217958
dgv2278n100 CNV gain 25217958
dgv2257n100 CNV gain 25217958
dgv2250n100 CNV gain+loss 25217958
dgv2246n100 CNV gain+loss 25217958
dgv2245n100 CNV loss 25217958
dgv2183n100 CNV loss 25217958
dgv2182n100 CNV gain 25217958
dgv2181n100 CNV gain 25217958
dgv2179n100 CNV gain 25217958
dgv2175n100 CNV gain 25217958
dgv2174n100 CNV gain 25217958
dgv1n1 OTHER inversion 15895083
dgv1360e59 CNV duplication 20981092
dgv1158n106 CNV duplication 24896259
nsv984125 CNV duplication 23825009
nsv977771 CNV duplication 23825009
nsv976880 CNV duplication 23825009

Variation tolerance for POTEB Gene

Gene Damage Index Score: 0.22; 4.87% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for POTEB Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for POTEB Gene

Disorders for POTEB Gene

Additional Disease Information for POTEB

Genetic Association Database
Human Genome Epidemiology Navigator
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for POTEB Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for POTEB Gene

Publications for POTEB Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58
  2. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody MC … Nusbaum C (Nature 2006) 3 4 58
  3. Five POTE paralogs and their splice variants are expressed in human prostate and encode proteins of different lengths. (PMID: 15276201) Bera TK … Pastan I (Gene 2004) 3 4 58
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  5. Personalized copy number and segmental duplication maps using next-generation sequencing. (PMID: 19718026) Alkan C … Eichler EE (Nature genetics 2009) 3 58

Products for POTEB Gene

Sources for POTEB Gene

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