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Aliases for POTEA Gene

Aliases for POTEA Gene

  • POTE Ankyrin Domain Family Member A 2 3 5
  • Prostate, Ovary, Testis-Expressed Protein On Chromosome 8 3 4
  • Cancer/Testis Antigen Family 104, Member 3 2 3
  • ANKRD26-Like Family A, Member 1 2 3
  • POTE-8 3 4
  • A26A1 3 4
  • POTE8 3 4
  • Protein Expressed In Prostate, Ovary, Testis, And Placenta 8 3
  • POTE Ankyrin Domain Family, Member A 2
  • ANKRD26-Like Family A Member 1 4
  • CT104.3 3

External Ids for POTEA Gene

Previous HGNC Symbols for POTEA Gene

  • A26A1

Previous GeneCards Identifiers for POTEA Gene

  • GC08P043147
  • GC08P041671

Summaries for POTEA Gene

GeneCards Summary for POTEA Gene

POTEA (POTE Ankyrin Domain Family Member A) is a Protein Coding gene. An important paralog of this gene is POTEJ.

Additional gene information for POTEA Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for POTEA Gene

Genomics for POTEA Gene

GeneHancer (GH) Regulatory Elements for POTEA Gene

Top Transcription factor binding sites by QIAGEN in the POTEA gene promoter:

Genomic Locations for POTEA Gene

Genomic Locations for POTEA Gene
74,038 bases
Plus strand

Genomic View for POTEA Gene

Genes around POTEA on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
POTEA Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for POTEA Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for POTEA Gene

Proteins for POTEA Gene

  • Protein details for POTEA Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    POTE ankyrin domain family member A
    Protein Accession:
    Secondary Accessions:
    • A6ND17
    • A6ND71
    • Q6S8J6

    Protein attributes for POTEA Gene

    498 amino acids
    Molecular mass:
    56166 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for POTEA Gene


neXtProt entry for POTEA Gene

Post-translational modifications for POTEA Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for POTEA Gene

No data available for DME Specific Peptides for POTEA Gene

Domains & Families for POTEA Gene

Protein Domains for POTEA Gene

Suggested Antigen Peptide Sequences for POTEA Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the POTE family.
  • Belongs to the POTE family.
genes like me logo Genes that share domains with POTEA: view

Function for POTEA Gene

genes like me logo Genes that share phenotypes with POTEA: view

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for POTEA Gene

Localization for POTEA Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for POTEA Gene

Pathways & Interactions for POTEA Gene

SuperPathways for POTEA Gene

No Data Available

Interacting Proteins for POTEA Gene

Gene Ontology (GO) - Biological Process for POTEA Gene


No data available for Pathways by source and SIGNOR curated interactions for POTEA Gene

Drugs & Compounds for POTEA Gene

No Compound Related Data Available

Transcripts for POTEA Gene

mRNA/cDNA for POTEA Gene

(3) REFSEQ mRNAs :
(3) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for POTEA Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13
SP2: -

Relevant External Links for POTEA Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for POTEA Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for POTEA Gene

mRNA differential expression in normal tissues according to GTEx for POTEA Gene

This gene is overexpressed in Testis (x53.0).

Protein differential expression in normal tissues from HIPED for POTEA Gene

This gene is overexpressed in Monocytes (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for POTEA Gene

Protein tissue co-expression partners for POTEA Gene

NURSA nuclear receptor signaling pathways regulating expression of POTEA Gene:


SOURCE GeneReport for Unigene cluster for POTEA Gene:

genes like me logo Genes that share expression patterns with POTEA: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for POTEA Gene

Orthologs for POTEA Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for POTEA Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia POTEA 33
  • 98.93 (n)
Species where no ortholog for POTEA was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for POTEA Gene

Gene Tree for POTEA (if available)
Gene Tree for POTEA (if available)

Paralogs for POTEA Gene

Variants for POTEA Gene

Sequence variations from dbSNP and Humsavar for POTEA Gene

SNP ID Clin Chr 08 pos Variation AA Info Type
rs1000029273 -- 43,348,189(+) G/A genic_downstream_transcript_variant, intron_variant
rs1000098067 -- 43,308,418(+) A/T intron_variant
rs1000139528 -- 43,345,120(+) A/G genic_downstream_transcript_variant, intron_variant
rs1000164598 -- 43,322,043(+) G/T genic_downstream_transcript_variant, intron_variant
rs1000201048 -- 43,327,205(+) C/G genic_downstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for POTEA Gene

Variant ID Type Subtype PubMed ID
dgv12123n54 CNV gain 21841781
dgv7187n100 CNV gain 25217958
dgv7188n100 CNV gain 25217958
dgv883n27 CNV gain 19166990
esv1935330 CNV deletion 18987734
esv2676692 CNV deletion 23128226
esv2736956 CNV deletion 23290073
esv3543436 CNV deletion 23714750
esv3576566 CNV gain 25503493
esv3617030 CNV loss 21293372
esv3617031 CNV gain 21293372
esv3617033 CNV gain 21293372
esv3617034 CNV gain 21293372
esv3891387 CNV gain 25118596
nsv1029330 CNV loss 25217958
nsv1032781 CNV gain 25217958
nsv465644 CNV gain 19166990
nsv470208 CNV gain 18288195
nsv519841 CNV gain+loss 19592680
nsv611147 CNV gain 21841781
nsv611150 CNV loss 21841781
nsv611151 CNV gain+loss 21841781
nsv819950 CNV loss 19587683
nsv971302 CNV duplication 23825009
nsv981932 CNV duplication 23825009

Additional Variant Information for POTEA Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for POTEA Gene

Disorders for POTEA Gene

Additional Disease Information for POTEA

No disorders were found for POTEA Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for POTEA Gene

Publications for POTEA Gene

  1. Five POTE paralogs and their splice variants are expressed in human prostate and encode proteins of different lengths. (PMID: 15276201) Bera TK … Pastan I (Gene 2004) 3 4 58
  2. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PMID: 17903299) Kathiresan S … Cupples LA (BMC medical genetics 2007) 44 58
  3. DNA sequence and analysis of human chromosome 8. (PMID: 16421571) Nusbaum C … Lander ES (Nature 2006) 4 58
  4. Duplication and extensive remodeling shaped POTE family genes encoding proteins containing ankyrin repeat and coiled coil domains. (PMID: 16364570) Hahn Y … Lee B (Gene 2006) 3 58
  5. POTE, a highly homologous gene family located on numerous chromosomes and expressed in prostate, ovary, testis, placenta, and prostate cancer. (PMID: 12475935) Bera TK … Pastan I (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for POTEA Gene

Sources for POTEA Gene

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