Aliases for POLR3D Gene
Aliases for POLR3D Gene
- RNA Polymerase III Subunit D 2 3 5
- Polymerase (RNA) III (DNA Directed) Polypeptide D, 44kDa 2 3
- BN51 (BHK21) Temperature Sensitivity Complementing 2 3
- DNA-Directed RNA Polymerase III Subunit D 3 4
- RNA Polymerase III 47 KDa Subunit 3 4
- RNA Polymerase III Subunit C4 3 4
- RPC53 Homolog 3 4
- BN51T 3 4
- Temperature Sensitive Complementation, Cell Cycle Specific, TsBN51 3
External Ids for POLR3D Gene
- HGNC: 1080
- Entrez Gene: 661
- Ensembl: ENSG00000168495
- OMIM: 187280
- UniProtKB: P05423
Previous HGNC Symbols for POLR3D Gene
- BN51T
Previous GeneCards Identifiers for POLR3D Gene
- GC08P022455
- GC08P021923
- GC08P022124
- GC08P022158
- GC08P022102
- GC08P020644
- GC08P022248
- GC08P022249
- GC08P022250
- GC08P022251
- GC08P022252
- GC08P022254
- GC08P022255
- GC08P022257
Summaries for POLR3D Gene
-
This gene complements a temperature-sensitive mutant isolated from the BHK-21 Syrian hamster cell line. It leads to a block in progression through the G1 phase of the cell cycle at nonpermissive temperatures. [provided by RefSeq, Jul 2008]
GeneCards Summary for POLR3D Gene
POLR3D (RNA Polymerase III Subunit D) is a Protein Coding gene. Among its related pathways are RNA Polymerase III Transcription Initiation and Pyrimidine metabolism (KEGG). Gene Ontology (GO) annotations related to this gene include chromatin binding and RNA polymerase III activity.
UniProtKB/Swiss-Prot for POLR3D Gene
-
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).
Additional gene information for POLR3D Gene
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for POLR3D Gene
Genomics for POLR3D Gene
GeneHancer (GH) Regulatory Elements for POLR3D Gene
Promoters and enhancers for POLR3D Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around POLR3D on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the POLR3D gene promoter:
-
- E2F-2
- Egr-2
- E2F-5
- E2F-4
- E2F-3a
- ZIC2
- E2F-1
- E2F
- NRSF form 1
- NRSF form 2
Regulatory Element Products
Genomic Locations for POLR3D Gene
Genomic Locations for POLR3D Gene
- chr8:22,245,104-22,254,600
- (GRCh38/hg38)
- Size:
- 9,497 bases
- Orientation:
- Plus strand
- chr8:22,102,617-22,112,113
- (GRCh37/hg19)
- Size:
- 9,497 bases
- Orientation:
- Plus strand
Genomic View for POLR3D Gene
Genes around POLR3D on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 8p21.3 by Entrez Gene
- 8p21.3 by HGNC
- 8p21.3 by Ensembl
POLR3D Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for POLR3D Gene
Proteins for POLR3D Gene
-
Protein details for POLR3D Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P05423-RPC4_HUMAN
- Recommended name:
- DNA-directed RNA polymerase III subunit RPC4
- Protein Accession:
- P05423
- Q6FI28
- Q9BPV7
- Q9BPZ1
- Q9BXB3
Protein attributes for POLR3D Gene
- Size:
- 398 amino acids
- Molecular mass:
- 44396 Da
- Quaternary structure:
-
- Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits (By similarity). Interacts with POLR3E/RPC5.
- SequenceCaution:
-
- Sequence=BC000516; Type=Frameshift; Positions=175; Evidence={ECO:0000305}; Sequence=BC003039; Type=Frameshift; Positions=175; Evidence={ECO:0000305};
Protein Expression for POLR3D Gene
Post-translational modifications for POLR3D Gene
Other Protein References for POLR3D Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for POLR3D
- Novus Biologicals Antibodies for POLR3D
-
Abcam antibodies for POLR3D
- Invitrogen Antibodies for POLR3D (AFLGC-POLR3D)
- Search GeneTex for Antibodies for POLR3D
Protein Products
-
OriGene Purified Proteins for POLR3D
- Search Origene for MassSpec and Protein Over-expression Lysates for POLR3D
- Origene Custom Protein Services for POLR3D
- antibodies-online: Search results for 8 available POLR3D Proteins ranked by validation data
- Compare Top POLR3D Proteins
-
Quality Products:
- Search GeneTex for Proteins for POLR3D
-
Abcam proteins for POLR3D
Assay Products
No data available for DME Specific Peptides for POLR3D Gene
Domains & Families for POLR3D Gene
Gene Families for POLR3D Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Suggested Antigen Peptide Sequences for POLR3D Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P05423UniProtKB/Swiss-Prot:
RPC4_HUMAN :- Belongs to the eukaryotic RPC4/POLR3D RNA polymerase subunit family.
- Family:
-
- Belongs to the eukaryotic RPC4/POLR3D RNA polymerase subunit family.
Function for POLR3D Gene
Molecular function for POLR3D Gene
- UniProtKB/Swiss-Prot Function:
- DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).
Phenotypes From GWAS Catalog for POLR3D Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001056 | contributes_to RNA polymerase III activity | IBA | -- |
| GO:0003677 | DNA binding | IEA | -- |
| GO:0003682 | chromatin binding | IEA | -- |
| GO:0003899 | DNA-directed 5-3 RNA polymerase activity | IEA | -- |
Phenotypes for POLR3D Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for POLR3D
-
CRISPR Products
-
OriGene CRISPR knockouts for POLR3D
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for POLR3D
- genomics-online: gRNA clones - Search results for available POLR3D gene related products
- Applied Biological Materials CRISPR for POLR3D
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for POLR3D
- GenScript: Design CRISPR guide RNA sequences for POLR3D
miRNA for POLR3D Gene
- miRTarBase miRNAs that target POLR3D
-
- hsa-mir-320a (MIRT001964)
- hsa-mir-149-5p (MIRT045444)
- hsa-let-7e-5p (MIRT051623)
- hsa-let-7a-5p (MIRT123972)
- hsa-let-7b-5p (MIRT123973)
- hsa-let-7c-5p (MIRT123974)
- hsa-let-7d-5p (MIRT123975)
- hsa-let-7f-5p (MIRT123976)
- hsa-mir-24-3p (MIRT123977)
- hsa-mir-98-5p (MIRT123978)
- hsa-let-7g-5p (MIRT123980)
- hsa-let-7i-5p (MIRT123981)
- hsa-mir-4458 (MIRT123990)
- hsa-mir-4500 (MIRT123991)
- hsa-mir-4446-5p (MIRT654920)
- hsa-mir-4753-3p (MIRT654921)
- hsa-mir-4279 (MIRT654922)
- hsa-mir-7111-3p (MIRT654923)
- hsa-mir-3156-3p (MIRT654924)
- hsa-mir-1260b (MIRT654925)
- hsa-mir-1260a (MIRT654926)
- hsa-mir-188-3p (MIRT654927)
- hsa-mir-8071 (MIRT654928)
- hsa-mir-627-3p (MIRT654929)
- hsa-mir-130b-5p (MIRT654930)
- hsa-mir-6769b-3p (MIRT654931)
- hsa-mir-4723-3p (MIRT654932)
- hsa-mir-3183 (MIRT654933)
- hsa-mir-665 (MIRT674362)
- hsa-mir-887-5p (MIRT674363)
- hsa-mir-6780a-5p (MIRT674364)
- hsa-mir-6779-5p (MIRT674365)
- hsa-mir-3689c (MIRT674366)
- hsa-mir-3689b-3p (MIRT674367)
- hsa-mir-3689a-3p (MIRT674368)
- hsa-mir-30b-3p (MIRT674369)
- hsa-mir-1273h-5p (MIRT674370)
- hsa-mir-6788-5p (MIRT674371)
- hsa-mir-30c-2-3p (MIRT674372)
- hsa-mir-30c-1-3p (MIRT674373)
- hsa-mir-7977 (MIRT674374)
- hsa-mir-6799-5p (MIRT674375)
- hsa-mir-6883-5p (MIRT674376)
- hsa-mir-6785-5p (MIRT674377)
- hsa-mir-4728-5p (MIRT674378)
- hsa-mir-149-3p (MIRT674379)
- hsa-mir-7106-5p (MIRT674380)
- hsa-mir-4284 (MIRT674381)
- hsa-mir-5693 (MIRT674382)
- hsa-mir-383-3p (MIRT674383)
- hsa-mir-3614-5p (MIRT674384)
- hsa-mir-6851-5p (MIRT700685)
- hsa-mir-3689d (MIRT700686)
- hsa-mir-4641 (MIRT700687)
- hsa-mir-5189-3p (MIRT700688)
- hsa-mir-4254 (MIRT700689)
- hsa-mir-4308 (MIRT700690)
- hsa-mir-6729-3p (MIRT700691)
- hsa-mir-136-3p (MIRT700692)
- hsa-mir-3651 (MIRT700693)
- hsa-mir-4678 (MIRT700694)
- hsa-mir-504-5p (MIRT700695)
- hsa-mir-6732-3p (MIRT700696)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for POLR3D
- Browse OriGene Inhibitory RNA Products For POLR3D
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for POLR3D
- genomics-online: shRNA clones - Search results for available POLR3D gene related products
Clone Products
- Sino Biological Human cDNA Clone for POLR3D
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for POLR3D
- genomics-online: cdna clones - Search results for available POLR3D gene related products
- orf clones - Search results for available POLR3D gene related products
- Applied Biological Materials Clones for POLR3D
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for POLR3D Gene
Localization for POLR3D Gene
Subcellular locations from UniProtKB/Swiss-Prot for POLR3D Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
- Nucleoplasm (4)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000790 | colocalizes_with nuclear chromatin | IDA | 24107381 |
| GO:0005634 | nucleus | IEA | -- |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005666 | DNA-directed RNA polymerase III complex | IDA,IEA | 24107381 |
| GO:0005829 | cytosol | TAS | -- |
Pathways & Interactions for POLR3D Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | RNA Polymerase III Transcription Initiation |
.45
|
|
| 2 | Pyrimidine metabolism (KEGG) | ||
| 3 | Transcription of tRNA | ||
| 4 | Innate Immune System |
.61
|
|
| 5 | RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways | ||
Pathways by source for POLR3D Gene
2 BioSystems pathways for POLR3D Gene
13 Reactome pathways for POLR3D Gene
6 KEGG pathways for POLR3D Gene
1 GeneGo (Thomson Reuters) pathway for POLR3D Gene
3 Qiagen pathways for POLR3D Gene
Interacting Proteins for POLR3D Gene
Selected Interacting proteins:
ENSP00000303088
P05423-RPC4_HUMAN
for POLR3D Gene via
STRING
MINT
IID
GPS-Prot Interaction Network for POLR3D
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002376 | immune system process | IEA | -- |
| GO:0006383 | transcription by RNA polymerase III | IEA | -- |
| GO:0032481 | positive regulation of type I interferon production | TAS | -- |
| GO:0032728 | positive regulation of interferon-beta production | IDA | 19631370 |
| GO:0045087 | innate immune response | IEA | -- |
No data available for SIGNOR curated interactions for POLR3D Gene
Drugs & Compounds for POLR3D Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Phosphoric acid | Approved | Pharma | 0 | |||
| Cytidine triphosphate | Experimental | Pharma | 0 | |||
| Guanosine triphosphate | Experimental | Pharma | 0 | |||
| Uridine triphosphate | Experimental, Investigational | Pharma | 0 | |||
| ATP | Investigational | Nutra | Agonist, Activator, Full agonist, Antagonist, Potentiation, Pore Blocker | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| pyrophosphate |
|
14000-31-8 |
|
Drug Products
Transcripts for POLR3D Gene
mRNA/cDNA for POLR3D Gene
- (1) REFSEQ mRNAs :
- (11) Additional mRNA sequences :
- (227) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000306433 1931 bps (uc003xbl.4)
- ENST00000519237 683 bps (uc064kzc.1)
- ENST00000397802 5494 bps (uc003xbm.4)
- ENST00000518039 1202 bps (uc064kzd.1)
- ENST00000517789 841 bps (uc064kze.1)
Unigene Clusters for POLR3D Gene
- Polymerase (RNA) III (DNA directed) polypeptide D, 44kDa:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for POLR3D
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for POLR3D
- genomics-online: gRNA clones - Search results for available POLR3D gene related products
- Applied Biological Materials CRISPR for POLR3D
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for POLR3D
- GenScript: Design CRISPR guide RNA sequences for POLR3D
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for POLR3D
- Browse OriGene Inhibitory RNA Products For POLR3D
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for POLR3D
- genomics-online: shRNA clones - Search results for available POLR3D gene related products
Clone Products
- Sino Biological Human cDNA Clone for POLR3D
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for POLR3D
- genomics-online: cdna clones - Search results for available POLR3D gene related products
- orf clones - Search results for available POLR3D gene related products
- Applied Biological Materials Clones for POLR3D
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||||||||
| SP3: |
Expression for POLR3D Gene
This gene is overexpressed in Adipocyte (12.3), Retina (8.8), Testis (7.3), and Gallbladder (7.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for POLR3D Gene
NURSA nuclear receptor signaling pathways regulating expression of POLR3D Gene:
POLR3DSOURCE GeneReport for Unigene cluster for POLR3D Gene:
Hs.148342Evidence on tissue expression from TISSUES for POLR3D Gene
- Lung(4.1)
- Nervous system(2.4)
Primer Products
-
OriGene qPCR primer pairs for POLR3D
-
OriGene qPCR primer pairs and template standards for POLR3D
- genomics-online: primer clones - Search results for available POLR3D gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for POLR3D Gene
Orthologs for POLR3D Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | POLR3D 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | POLR3D 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | POLR3D 34 33 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Polr3d 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Polr3d 16 34 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | POLR3D 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | POLR3D 34 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | POLR3D 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | polr3d 33 |
|
||
| Str.12617 33 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.31157 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | polr3d 34 33 |
|
OneToOne | |
| zgc56407 33 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | CG5147 34 |
|
OneToOne | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToOne |
- Species where no ortholog for POLR3D was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for POLR3D Gene
- ENSEMBL:
- Gene Tree for POLR3D (if available)
- TreeFam:
- Gene Tree for POLR3D (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for POLR3D: view image
Paralogs for POLR3D Gene
Pseudogenes.org Pseudogenes for POLR3D Gene
No data available for Paralogs for POLR3D Gene
Variants for POLR3D Gene
| SNP ID | Clin | Chr 08 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1001190133 | -- | 22,244,676(+) | G/T | upstream_transcript_variant | |
| rs1001472735 | -- | 22,245,249(+) | G/A/T | intron_variant | |
| rs1001620135 | -- | 22,244,493(+) | A/C | upstream_transcript_variant | |
| rs1002475428 | -- | 22,246,166(+) | C/A | intron_variant | |
| rs1002890766 | -- | 22,245,167(+) | G/A | 5_prime_UTR_variant, non_coding_transcript_variant |
Residual Variation Intolerance Score:
35.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.21;
39.92% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for POLR3D Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- POLR3D
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for POLR3D Gene
Disorders for POLR3D Gene
Additional Disease Information for POLR3D
No disorders were found for POLR3D Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for POLR3D Gene
Publications for POLR3D Gene
- Characterization of human RNA polymerase III identifies orthologues for Saccharomyces cerevisiae RNA polymerase III subunits. (PMID: 12391170) Hu P … Hernandez N (Molecular and cellular biology 2002) 2 3 4 58
- Reconstitution of transcription from the human U6 small nuclear RNA promoter with eight recombinant polypeptides and a partially purified RNA polymerase III complex. (PMID: 11279001) Chong SS … Hernandez N (The Journal of biological chemistry 2001) 2 3 4 58
- RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway. (PMID: 19631370) Chiu YH … Chen ZJ (Cell 2009) 3 4 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
- The BN51 protein is a polymerase (Pol)-specific subunit of RNA Pol III which reveals a link between Pol III transcription and pre-rRNA processing. (PMID: 7799973) Jackson AJ … Pugh BF (Molecular and cellular biology 1995) 3 22 58
Products for POLR3D Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Human Proteins and Enzymes
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for POLR3D
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for POLR3D
- Search Origene for MassSpec and Protein Over-expression Lysates for POLR3D
- Origene Custom Protein Services for POLR3D
- Origene shrna, sirna, and RNAi products in human, mouse, rat for POLR3D
- Browse OriGene Inhibitory RNA Products For POLR3D
- OriGene qPCR primer pairs for POLR3D
- OriGene qPCR primer pairs and template standards for POLR3D
- OriGene CRISPR knockouts for POLR3D
- OriGene ORF clones in human for POLR3D
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For POLR3D
- GenScript: Next-day shipping of latest version cDNA ORF clones for POLR3D in any vector
- GenScript Custom Purified and Recombinant Proteins Services for POLR3D
- GenScript Custom Assay Services for POLR3D
- GenScript Custom overexpressing Cell Line Services for POLR3D
- GenScript: Design CRISPR guide RNA sequences for POLR3D
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for POLR3D
- Sino Biological Human cDNA Clone for POLR3D
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for POLR3D
- Novus Biologicals lysates and proteins for POLR3D
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for POLR3D
- Abcam proteins for POLR3D
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for POLR3D (AFLGC-POLR3D)
- Cyagen custom Knockout/knockin (KOKI) mouse models for POLR3D
- antibodies-online: Search results for 50 available POLR3D Antibodies ranked by validation data
- Compare Top POLR3D Antibodies
- antibodies-online: Search results for available POLR3D related products ranked by validation data
- antibodies-online: Search results for 8 available POLR3D Proteins ranked by validation data
- Compare Top POLR3D Proteins
- Quality Products:
- Search GeneTex for Antibodies for POLR3D
- Search GeneTex for Proteins for POLR3D
- genomics-online: cdna clones - Search results for available POLR3D gene related products
- orf clones - Search results for available POLR3D gene related products
- genomics-online: gRNA clones - Search results for available POLR3D gene related products
- genomics-online: primer clones - Search results for available POLR3D gene related products
- genomics-online: shRNA clones - Search results for available POLR3D gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for POLR3D
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for POLR3D
- GeneCopoeia miRNA 3'UTR Target clone products for POLR3D
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for POLR3D
Sources for POLR3D Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt