Aliases for POLR1H Gene
External Ids for POLR1H Gene
Previous HGNC Symbols for POLR1H Gene
Previous GeneCards Identifiers for POLR1H Gene
This gene encodes a DNA-directed RNA polymerase I subunit. The encoded protein contains two potential zinc-binding motifs and may play a role in regulation of cell proliferation. The encoded protein may be involved in cancer and human immunodeficiency virus progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
GeneCards Summary for POLR1H Gene
POLR1H (RNA Polymerase I Subunit H) is a Protein Coding gene. Diseases associated with POLR1H include Asthma, Nasal Polyps, And Aspirin Intolerance and Plantar Wart. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and RNA Polymerase III Transcription Initiation. An important paralog of this gene is POLR3K.
UniProtKB/Swiss-Prot Summary for POLR1H Gene
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors.