Aliases for POLR1H Gene
External Ids for POLR1H Gene
Previous HGNC Symbols for POLR1H Gene
This gene encodes a DNA-directed RNA polymerase I subunit. The encoded protein contains two potential zinc-binding motifs and may play a role in regulation of cell proliferation. The encoded protein may be involved in cancer and human immunodeficiency virus progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
GeneCards Summary for POLR1H Gene
POLR1H (RNA Polymerase I Subunit H) is a Protein Coding gene. Diseases associated with POLR1H include Asthma, Nasal Polyps, And Aspirin Intolerance and Gastric Cancer. Among its related pathways are RNA Polymerase I Promoter Escape and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. An important paralog of this gene is POLR3K.
UniProtKB/Swiss-Prot Summary for POLR1H Gene
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors.