The protein encoded by this gene is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Mutations in this gene have been associated with Treacher Collins syndrome (TCS) and hypomyelinating leukodystrophy 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] See more...

Aliases for POLR1C Gene

Aliases for POLR1C Gene

  • RNA Polymerase I And III Subunit C 2 3 5
  • RPA39 2 3 4
  • RPA40 2 3 4
  • RPC40 2 3 4
  • AC40 2 3 4
  • DNA-Directed RNA Polymerases I And III 40 KDa Polypeptide 3 4
  • DNA-Directed RNA Polymerases I And III Subunit RPAC1 3 4
  • Polymerase (RNA) I Polypeptide C, 30kDa 2 3
  • DNA-Directed RNA Polymerase I Subunit C 3 4
  • RNA Polymerases I And III Subunit AC1 3 4
  • RNA Polymerase I Subunit C 2 3
  • RPAC1 2 3
  • RPA5 2 3
  • Polymerase (RNA) I Subunit C 3
  • POLR1C 5
  • POLR1E 4
  • HLD11 3
  • TCS3 3

External Ids for POLR1C Gene

Previous GeneCards Identifiers for POLR1C Gene

  • GC06P043481
  • GC06P043531
  • GC06P043592
  • GC06P043484
  • GC06P043202
  • GC06P044223
  • GC06P044243
  • GC06P044087
  • GC06P046124
  • GC06P043764
  • GC06P047537
  • GC06P049590

Summaries for POLR1C Gene

Entrez Gene Summary for POLR1C Gene

  • The protein encoded by this gene is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Mutations in this gene have been associated with Treacher Collins syndrome (TCS) and hypomyelinating leukodystrophy 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

GeneCards Summary for POLR1C Gene

POLR1C (RNA Polymerase I And III Subunit C) is a Protein Coding gene. Diseases associated with POLR1C include Treacher Collins Syndrome 3 and Leukodystrophy, Hypomyelinating, 11. Among its related pathways are RNA Polymerase III Transcription Initiation and ATP/ITP metabolism. Gene Ontology (GO) annotations related to this gene include protein dimerization activity and RNA polymerase III activity. An important paralog of this gene is POLR2C.

UniProtKB/Swiss-Prot Summary for POLR1C Gene

  • DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. RPAC1 is part of the Pol core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity).

Gene Wiki entry for POLR1C Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for POLR1C Gene

Genomics for POLR1C Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for POLR1C Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around POLR1C on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for POLR1C

Top Transcription factor binding sites by QIAGEN in the POLR1C gene promoter:
  • c-Myb
  • CUTL1
  • FOXD1
  • GR
  • GR-beta
  • RP58
  • RREB-1
  • SRF
  • SRF (504 AA)
  • STAT3

Genomic Locations for POLR1C Gene

Latest Assembly
chr6:43,509,702-44,461,400
(GRCh38/hg38)
Size:
951,699 bases
Orientation:
Plus strand

Previous Assembly
chr6:43,484,827-43,530,144
(GRCh37/hg19 by Entrez Gene)
Size:
45,318 bases
Orientation:
Plus strand

chr6:43,477,440-43,497,323
(GRCh37/hg19 by Ensembl)
Size:
19,884 bases
Orientation:
Plus strand

Genomic View for POLR1C Gene

Genes around POLR1C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
POLR1C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for POLR1C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for POLR1C Gene

Proteins for POLR1C Gene

  • Protein details for POLR1C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O15160-RPAC1_HUMAN
    Recommended name:
    DNA-directed RNA polymerases I and III subunit RPAC1
    Protein Accession:
    O15160
    Secondary Accessions:
    • O75395
    • Q5JTE3

    Protein attributes for POLR1C Gene

    Size:
    346 amino acids
    Molecular mass:
    39250 Da
    Quaternary structure:
    • Component of the RNA polymerase I (Pol I) and RNA polymerase III (Pol III) complexes consisting of at least 13 and 17 subunits, respectively.

    Alternative splice isoforms for POLR1C Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for POLR1C Gene

Post-translational modifications for POLR1C Gene

  • Ubiquitination at Lys167 and Lys224
  • Modification sites at PhosphoSitePlus

Antibodies for research

  • Abcam antibodies for POLR1C

No data available for DME Specific Peptides for POLR1C Gene

Domains & Families for POLR1C Gene

Gene Families for POLR1C Gene

HGNC:
Human Protein Atlas (HPA):
  • Disease related genes
  • Predicted intracellular proteins

Protein Domains for POLR1C Gene

Suggested Antigen Peptide Sequences for POLR1C Gene

GenScript: Design optimal peptide antigens:
  • Polymerase (RNA) I polypeptide C, 30kDa (Q5JTD9_HUMAN)
  • Polymerase (RNA) I polypeptide C, 30kDa (Q5JTE0_HUMAN)
  • Polymerase (RNA) I polypeptide C, 30kDa (Q5JTE1_HUMAN)
  • Polymerase (RNA) I polypeptide C, 30kDa (Q5JTE2_HUMAN)
  • Polymerase (RNA) I polypeptide C, 30kDa (Q5JTE4_HUMAN)

Graphical View of Domain Structure for InterPro Entry

O15160

UniProtKB/Swiss-Prot:

RPAC1_HUMAN :
  • Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family.
Family:
  • Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family.
genes like me logo Genes that share domains with POLR1C: view

Function for POLR1C Gene

Molecular function for POLR1C Gene

UniProtKB/Swiss-Prot Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. RPAC1 is part of the Pol core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity).

Phenotypes From GWAS Catalog for POLR1C Gene

Gene Ontology (GO) - Molecular Function for POLR1C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001054 contributes_to RNA polymerase I activity IEA,IBA 21873635
GO:0001056 contributes_to RNA polymerase III activity IEA,IBA 21873635
GO:0003677 DNA binding IEA --
GO:0003899 contributes_to DNA-directed 5'-3' RNA polymerase activity IEA,IBA 21873635
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with POLR1C: view
genes like me logo Genes that share phenotypes with POLR1C: view

Human Phenotype Ontology for POLR1C Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

miRNA for POLR1C Gene

miRTarBase miRNAs that target POLR1C

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for POLR1C

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for POLR1C Gene

Localization for POLR1C Gene

Subcellular locations from UniProtKB/Swiss-Prot for POLR1C Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for POLR1C gene
Compartment Confidence
nucleus 5
cytosol 4
cytoskeleton 1
mitochondrion 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for POLR1C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005654 nucleoplasm TAS --
GO:0005666 RNA polymerase III complex IDA 24107381
GO:0005736 RNA polymerase I complex TAS,IBA 21873635
GO:0005829 cytosol TAS --
genes like me logo Genes that share ontologies with POLR1C: view

Pathways & Interactions for POLR1C Gene

genes like me logo Genes that share pathways with POLR1C: view

Pathways by source for POLR1C Gene

1 GeneGo (Thomson Reuters) pathway for POLR1C Gene
  • ATP/ITP metabolism
3 Qiagen pathways for POLR1C Gene
  • Assembly of RNA Polymerase-I Initiation Complex
  • DNA Repair Mechanisms
  • Inhibition of Ribosome Biogenesis by p14(ARF)

Gene Ontology (GO) - Biological Process for POLR1C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006360 transcription by RNA polymerase I IEA,TAS 9540830
GO:0006361 transcription initiation from RNA polymerase I promoter TAS --
GO:0006362 transcription elongation from RNA polymerase I promoter TAS --
GO:0006363 termination of RNA polymerase I transcription TAS --
genes like me logo Genes that share ontologies with POLR1C: view

No data available for SIGNOR curated interactions for POLR1C Gene

Drugs & Compounds for POLR1C Gene

(16) Drugs for POLR1C Gene - From: ApexBio, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Cytidine triphosphate Experimental Pharma 0
Guanosine triphosphate Experimental Pharma 0
Phosphate Experimental Pharma 0
Uridine triphosphate Experimental, Investigational Pharma 0
ATP Investigational Nutra 0

(10) Additional Compounds for POLR1C Gene - From: HMDB and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
pyrophosphate
  • [(HO)2P(O)OP(O)(OH)2]
  • Acide diphosphorique
  • Diphosphorsaeure
  • H4P2O7
  • Pyrophosphoric acid
14000-31-8

(3) ApexBio Compounds for POLR1C Gene

Compound Action Cas Number
BMH-21 RNA polymerase I Inhibitior 896705-16-1
CX-5461 Pol I-mediated rRNA synthesis inhibitor 1138549-36-6
Foscarnet Sodium 63585-09-1
genes like me logo Genes that share compounds with POLR1C: view

Drug products for research

Transcripts for POLR1C Gene

mRNA/cDNA for POLR1C Gene

4 REFSEQ mRNAs :
8 NCBI additional mRNA sequence :
16 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for POLR1C

Alternative Splicing Database (ASD) splice patterns (SP) for POLR1C Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b ^ 9 ^ 10
SP1: -
SP2:
SP3:
SP4: - -
SP5:
SP6:
SP7:

Relevant External Links for POLR1C Gene

GeneLoc Exon Structure for
POLR1C

Expression for POLR1C Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for POLR1C Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for POLR1C Gene

This gene is overexpressed in Peripheral blood mononuclear cells (15.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for POLR1C Gene



Protein tissue co-expression partners for POLR1C Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for POLR1C

SOURCE GeneReport for Unigene cluster for POLR1C Gene:

Hs.743509

Evidence on tissue expression from TISSUES for POLR1C Gene

  • Nervous system(4.6)
  • Blood(4.3)
  • Liver(3.9)
  • Skin(2.1)

Phenotype-based relationships between genes and organs from Gene ORGANizer for POLR1C Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • digestive
  • endocrine
  • integumentary
  • nervous
  • reproductive
  • respiratory
  • skeletal muscle
  • skeleton
Regions:
Head and neck:
  • brain
  • cerebellum
  • cheek
  • chin
  • cranial nerve
  • ear
  • eye
  • eyelid
  • face
  • forehead
  • head
  • inner ear
  • jaw
  • lip
  • mandible
  • maxilla
  • middle ear
  • mouth
  • neck
  • nose
  • outer ear
  • pharynx
  • pituitary gland
  • salivary gland
  • scalp
  • skull
  • tooth
Thorax:
  • breast
  • chest wall
  • clavicle
  • esophagus
  • rib
  • rib cage
  • scapula
  • sternum
Abdomen:
  • stomach
Pelvis:
  • fallopian tube
  • ovary
  • pelvis
  • penis
  • prostate
  • testicle
  • uterus
  • vagina
  • vas deferens
  • vulva
Limb:
  • ankle
  • arm
  • digit
  • elbow
  • femur
  • fibula
  • finger
  • foot
  • forearm
  • hand
  • hip
  • humerus
  • knee
  • lower limb
  • radius
  • shin
  • shoulder
  • thigh
  • tibia
  • toe
  • ulna
  • upper limb
  • wrist
General:
  • hair
  • peripheral nervous system
  • skin
  • spinal column
  • spinal cord
  • vertebrae
genes like me logo Genes that share expression patterns with POLR1C: view

Primer products for research

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for POLR1C Gene

Orthologs for POLR1C Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for POLR1C Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia POLR1C 29 30
  • 99.52 (n)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia POLR1C 30
  • 91 (a)
OneToOne
Dog
(Canis familiaris)
Mammalia POLR1C 29 30
  • 90.94 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia POLR1C 29 30
  • 88.92 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Polr1c 29
  • 86.71 (n)
Mouse
(Mus musculus)
Mammalia Polr1c 29 16 30
  • 86.42 (n)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia POLR1C 30
  • 86 (a)
OneToOne
Chicken
(Gallus gallus)
Aves POLR1C 29 30
  • 75.14 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia POLR1C 30
  • 72 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia polr1c 29
  • 68.58 (n)
Zebrafish
(Danio rerio)
Actinopterygii polr1c 29 30
  • 68.79 (n)
OneToOne
zgc65973 29
Fruit Fly
(Drosophila melanogaster)
Insecta CG3756 29 30
  • 57.74 (n)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP012796 29
  • 57.46 (n)
Worm
(Caenorhabditis elegans)
Secernentea H43I07.2 29
  • 52.09 (n)
rpac-40 30
  • 43 (a)
OneToOne
A. gosspyii yeast
(Eremothecium gossypii)
Saccharomycetes AGOS_ADR031C 29
  • 52.94 (n)
K. Lactis Yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0D14861g 29
  • 52.83 (n)
Baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RPC40 29 30
  • 52.04 (n)
OneToOne
Thale Cress
(Arabidopsis thaliana)
eudicotyledons RPAC43 29
  • 54.72 (n)
Rice
(Oryza sativa)
Liliopsida Os03g0295400 29
  • 51.89 (n)
Os.18198 29
Wheat
(Triticum aestivum)
Liliopsida Ta.4262 29
Corn
(Zea mays)
Liliopsida Zm.6471 29
Bread mold
(Neurospora crassa)
Ascomycetes NCU02533 29
  • 54.23 (n)
Fission Yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes rpc40 29
  • 53.37 (n)
Sea Vase
(Ciona intestinalis)
Ascidiacea Cin.5013 29
Species where no ortholog for POLR1C was found in the sources mined by GeneCards:
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)

Evolution for POLR1C Gene

ENSEMBL:
Gene Tree for POLR1C (if available)
TreeFam:
Gene Tree for POLR1C (if available)
Aminode:
Evolutionary constrained regions (ECRs) for POLR1C: view image
Alliance of Genome Resources:
Additional Orthologs for POLR1C

Paralogs for POLR1C Gene

Paralogs for POLR1C Gene

genes like me logo Genes that share paralogs with POLR1C: view

Variants for POLR1C Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for POLR1C Gene

SNP ID Clinical significance and condition Chr 06 pos Variation AA Info Type
1005619 Uncertain Significance: Primary ciliary dyskinesia 43,655,574(+) G/C
NM_152732.5(RSPH9):c.406G>C (p.Glu136Gln)
MISSENSE_VARIANT,INTRON
1007657 Uncertain Significance: not provided 43,770,712(+) G/GGA
NM_001025366.3(VEGFA):c.7_8dup (p.Asp3fs)
FRAMESHIFT_VARIANT,FIVE_PRIME_UTR
1018887 Uncertain Significance: Primary ciliary dyskinesia 43,670,836(+) C/T
NM_152732.5(RSPH9):c.718C>T (p.Arg240Cys)
MISSENSE
1023203 Uncertain Significance: Primary ciliary dyskinesia 43,645,123(+) T/C
NM_152732.5(RSPH9):c.25T>C (p.Ser9Pro)
MISSENSE
1030725 Uncertain Significance: Combined oxidative phosphorylation deficiency 8 44,306,525(+) G/A
NM_020745.4(AARS2):c.1157C>T (p.Ala386Val)
MISSENSE

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for POLR1C Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for POLR1C Gene

Variant ID Type Subtype PubMed ID
nsv603000 CNV loss 21841781
nsv818414 CNV gain 17921354

Variation tolerance for POLR1C Gene

Residual Variation Intolerance Score: 43.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.94; 49.13% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for POLR1C Gene

Human Gene Mutation Database (HGMD)
POLR1C
SNPedia medical, phenotypic, and genealogical associations of SNPs for
POLR1C
Leiden Open Variation Database (LOVD)
POLR1C

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for POLR1C Gene

Disorders for POLR1C Gene

MalaCards: The human disease database

(28) MalaCards diseases for POLR1C Gene - From: OMI, CVR, GTR, ORP, SWI, COP, and GCD

- elite association - COSMIC cancer census association via MalaCards

UniProtKB/Swiss-Prot

RPAC1_HUMAN
  • Treacher Collins syndrome 3 (TCS3) [MIM:248390]: A form of Treacher Collins syndrome, a disorder of craniofacial development. Treacher Collins syndrome is characterized by a combination of bilateral downward slanting of the palpebral fissures, colobomas of the lower eyelids with a paucity of eyelashes medial to the defect, hypoplasia of the facial bones, cleft palate, malformation of the external ears, atresia of the external auditory canals, and bilateral conductive hearing loss. {ECO:0000269 PubMed:21131976, ECO:0000269 PubMed:26151409}. Note=The disease is caused by variants affecting the gene represented in this entry.
  • Leukodystrophy, hypomyelinating, 11 (HLD11) [MIM:616494]: An autosomal recessive neurologic disorder characterized by brain hypomyelination, delayed psychomotor development, intellectual disability, tremor and other neurologic symptoms. Some patients may additionally manifest non-neurologic features, particularly dental abnormalities and hypogonadotropic hypogonadism. {ECO:0000269 PubMed:26151409}. Note=The disease is caused by variants affecting the gene represented in this entry.

Additional Disease Information for POLR1C

genes like me logo Genes that share disorders with POLR1C: view

No data available for Genatlas for POLR1C Gene

Publications for POLR1C Gene

  1. Recessive mutations in POLR1C cause a leukodystrophy by impairing biogenesis of RNA polymerase III. (PMID: 26151409) Thiffault I … Bernard G (Nature communications 2015) 3 4 72
  2. Mutations in genes encoding subunits of RNA polymerases I and III cause Treacher Collins syndrome. (PMID: 21131976) Dauwerse JG … Wieczorek D (Nature genetics 2011) 3 4 72
  3. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PMID: 15592455) Rush J … Comb MJ (Nature biotechnology 2005) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
  5. Treacher Collins Syndrome (PMID: 20301704) Katsanis SH … Jabs EW (GeneReviews® 2004) 3 72

Products for POLR1C Gene