Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa... See more...

Aliases for POLR1B Gene

Aliases for POLR1B Gene

  • RNA Polymerase I Subunit B 2 3 5
  • RPA135 2 3 4
  • DNA-Directed RNA Polymerase I 135 KDa Polypeptide 3 4
  • DNA-Directed RNA Polymerase I Subunit RPA2 3 4
  • Polymerase (RNA) I Polypeptide B, 128kDa 2 3
  • RNA Polymerase I Subunit 2 3 4
  • EC 2.7.7.6 4 50
  • Rpo1-2 2 3
  • RPA2 2 3
  • DNA-Directed RNA Polymerase I 135kDa Polypeptide 3
  • Polymerase (RNA) I Subunit B 3
  • FLJ21921 2
  • FLJ10816 2
  • POLR1B 5
  • A135 3
  • TCS4 3

External Ids for POLR1B Gene

Previous GeneCards Identifiers for POLR1B Gene

  • GC02P111221
  • GC02P113206
  • GC02P113395
  • GC02P113015
  • GC02P113299
  • GC02P105754
  • GC02P112567
  • GC02P113953
  • GC02P114204
  • GC02P114248
  • GC02P114891
  • GC02P112674
  • GC02P112822
  • GC02P112908
  • GC02P113130
  • GC02P113355
  • GC02P113592
  • GC02P113818
  • GC02P115296
  • GC02P115711

Summaries for POLR1B Gene

Entrez Gene Summary for POLR1B Gene

  • Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996 [PubMed 8921381]).[supplied by OMIM, Mar 2008]

GeneCards Summary for POLR1B Gene

POLR1B (RNA Polymerase I Subunit B) is a Protein Coding gene. Diseases associated with POLR1B include Treacher Collins Syndrome 4. Among its related pathways are ATP/ITP metabolism and Chks in Checkpoint Regulation. Gene Ontology (GO) annotations related to this gene include DNA-directed 5'-3' RNA polymerase activity and ribonucleoside binding. An important paralog of this gene is POLR3B.

UniProtKB/Swiss-Prot Summary for POLR1B Gene

  • DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity).

Gene Wiki entry for POLR1B Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for POLR1B Gene

Genomics for POLR1B Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for POLR1B Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around POLR1B on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for POLR1B

Top Transcription factor binding sites by QIAGEN in the POLR1B gene promoter:
  • AREB6
  • CREB
  • CUTL1
  • E47
  • LCR-F1
  • Lmo2
  • Pax-4a
  • Tal-1
  • TGIF

Genomic Locations for POLR1B Gene

Latest Assembly
chr2:112,541,915-112,579,818
(GRCh38/hg38)
Size:
37,904 bases
Orientation:
Plus strand

Previous Assembly
chr2:113,299,613-113,337,395
(GRCh37/hg19 by Entrez Gene)
Size:
37,783 bases
Orientation:
Plus strand

chr2:113,299,492-113,334,635
(GRCh37/hg19 by Ensembl)
Size:
35,144 bases
Orientation:
Plus strand

Genomic View for POLR1B Gene

Genes around POLR1B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
POLR1B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for POLR1B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for POLR1B Gene

Proteins for POLR1B Gene

  • Protein details for POLR1B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H9Y6-RPA2_HUMAN
    Recommended name:
    DNA-directed RNA polymerase I subunit RPA2
    Protein Accession:
    Q9H9Y6
    Secondary Accessions:
    • B7Z6Y7
    • B7Z823
    • F5GZX4
    • F8W898
    • Q2TAM4
    • Q585T5
    • Q6ZRR2
    • Q9H9D3

    Protein attributes for POLR1B Gene

    Size:
    1135 amino acids
    Molecular mass:
    128229 Da
    Quaternary structure:
    • Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits.

    Alternative splice isoforms for POLR1B Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for POLR1B Gene

Selected DME Specific Peptides for POLR1B Gene

Q9H9Y6:
  • FGEMERD
  • DNPDSLVNQEVL
  • YQRLRHMV
  • PSRMTIG
  • GDKFASR
  • NPHGFPSRMT
  • GGYFIING
  • YGTERLYSG
  • CPVHTPDG
  • EKVIRMLI
  • VAVISYTGYD
  • VPKGTICK
  • DSGLCVVADKLNF
  • RYLSHFRCVHRGA
  • QMGKQTMG
  • TGYDMEDAMI
  • NQSPRNMYQCQM

Post-translational modifications for POLR1B Gene

  • Ubiquitination at Lys17, Lys94, and Lys442
  • Modification sites at PhosphoSitePlus

Antibodies for research

  • Abcam antibodies for POLR1B
  • Santa Cruz Biotechnology (SCBT) Antibodies for POLR1B

Domains & Families for POLR1B Gene

Gene Families for POLR1B Gene

HGNC:
Human Protein Atlas (HPA):
  • Enzymes
  • Plasma proteins
  • Predicted intracellular proteins

Protein Domains for POLR1B Gene

InterPro:
Blocks:
  • RNA polymerase Rpb2, domain 6
  • RNA polymerase, beta subunit
  • RNA polymerase Rpb2, domain 5
  • RNA polymerase I, Rpa2 specific

Suggested Antigen Peptide Sequences for POLR1B Gene

GenScript: Design optimal peptide antigens:
  • DNA-directed RNA polymerase (F5GWZ8_HUMAN)
  • DNA-directed RNA polymerase (F5GZX4_HUMAN)
  • DNA-directed RNA polymerase (F5H643_HUMAN)
  • DNA-directed RNA polymerase (Q2TAM4_HUMAN)
  • DNA-directed RNA polymerase (Q4QRK8_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q9H9Y6

UniProtKB/Swiss-Prot:

RPA2_HUMAN :
  • Belongs to the RNA polymerase beta chain family.
Family:
  • Belongs to the RNA polymerase beta chain family.
genes like me logo Genes that share domains with POLR1B: view

Function for POLR1B Gene

Molecular function for POLR1B Gene

UniProtKB/Swiss-Prot Function:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity).
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:11128, Rhea:RHEA-COMP:11129, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:83400; EC=2.7.7.6;.

Enzyme Numbers (IUBMB) for POLR1B Gene

Phenotypes From GWAS Catalog for POLR1B Gene

Gene Ontology (GO) - Molecular Function for POLR1B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003899 contributes_to DNA-directed 5'-3' RNA polymerase activity IBA 21873635
GO:0005515 protein binding IPI 16514417
GO:0016740 transferase activity IEA --
GO:0016779 nucleotidyltransferase activity IEA --
genes like me logo Genes that share ontologies with POLR1B: view
genes like me logo Genes that share phenotypes with POLR1B: view

Human Phenotype Ontology for POLR1B Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

miRNA for POLR1B Gene

miRTarBase miRNAs that target POLR1B

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for POLR1B

Clone products for research

No data available for Animal Models , Transcription Factor Targets and HOMER Transcription for POLR1B Gene

Localization for POLR1B Gene

Subcellular locations from UniProtKB/Swiss-Prot for POLR1B Gene

Nucleus, nucleolus. Chromosome.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for POLR1B gene
Compartment Confidence
nucleus 5
cytosol 5
plasma membrane 1
extracellular 1
cytoskeleton 1
mitochondrion 1
peroxisome 0

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoli (3)
  • Cytosol (1)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for POLR1B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005654 nucleoplasm TAS --
GO:0005694 chromosome ISS --
GO:0005730 nucleolus IEA,IDA --
GO:0005736 RNA polymerase I complex IBA 21873635
genes like me logo Genes that share ontologies with POLR1B: view

Pathways & Interactions for POLR1B Gene

genes like me logo Genes that share pathways with POLR1B: view

Pathways by source for POLR1B Gene

1 GeneGo (Thomson Reuters) pathway for POLR1B Gene
  • ATP/ITP metabolism
3 Qiagen pathways for POLR1B Gene
  • Assembly of RNA Polymerase-I Initiation Complex
  • DNA Repair Mechanisms
  • Inhibition of Ribosome Biogenesis by p14(ARF)

Gene Ontology (GO) - Biological Process for POLR1B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006361 transcription initiation from RNA polymerase I promoter TAS --
GO:0006362 transcription elongation from RNA polymerase I promoter TAS --
GO:0006363 termination of RNA polymerase I transcription TAS --
GO:0007566 embryo implantation IEA --
genes like me logo Genes that share ontologies with POLR1B: view

No data available for SIGNOR curated interactions for POLR1B Gene

Drugs & Compounds for POLR1B Gene

(7) Drugs for POLR1B Gene - From: ApexBio and HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Cytidine triphosphate Experimental Pharma 0
Guanosine triphosphate Experimental Pharma 0
Phosphate Experimental Pharma 0
Thymidine 5'-triphosphate Experimental Pharma 0
Uridine triphosphate Experimental, Investigational Pharma 0

(1) Additional Compounds for POLR1B Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
pyrophosphate
  • [(HO)2P(O)OP(O)(OH)2]
  • Acide diphosphorique
  • Diphosphorsaeure
  • H4P2O7
  • Pyrophosphoric acid
14000-31-8

(1) ApexBio Compounds for POLR1B Gene

Compound Action Cas Number
BMH-21 RNA polymerase I Inhibitior 896705-16-1
genes like me logo Genes that share compounds with POLR1B: view

Drug products for research

Transcripts for POLR1B Gene

mRNA/cDNA for POLR1B Gene

10 REFSEQ mRNAs :
17 NCBI additional mRNA sequence :
17 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for POLR1B

Clone products for research

Alternative Splicing Database (ASD) splice patterns (SP) for POLR1B Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15a · 15b ^ 16 ^ 17 ^ 18 ^ 19a ·
SP1: - - - - - -
SP2: - - - - - - -
SP3: - - - - - - - - -
SP4: -
SP5:
SP6: -
SP7:
SP8: - - - -

ExUns: 19b ^ 20 ^ 21
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:

Relevant External Links for POLR1B Gene

GeneLoc Exon Structure for
POLR1B

Expression for POLR1B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for POLR1B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for POLR1B Gene

This gene is overexpressed in Liver, secretome (11.4), Lymph node (11.0), and Peripheral blood mononuclear cells (10.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for POLR1B Gene



Protein tissue co-expression partners for POLR1B Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for POLR1B

SOURCE GeneReport for Unigene cluster for POLR1B Gene:

Hs.745127

Evidence on tissue expression from TISSUES for POLR1B Gene

  • Spleen(4.2)
  • Pancreas(4.1)
  • Nervous system(3.3)
genes like me logo Genes that share expression patterns with POLR1B: view

Primer products for research

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for POLR1B Gene

Orthologs for POLR1B Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for POLR1B Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia POLR1B 29 30
  • 99.47 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia POLR1B 29 30
  • 90.81 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia POLR1B 29 30
  • 88.93 (n)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia POLR1B 30
  • 87 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia POLR1B 30
  • 86 (a)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Polr1b 29
  • 85.47 (n)
Mouse
(Mus musculus)
Mammalia Polr1b 29 16 30
  • 84.96 (n)
OneToOne
Chicken
(Gallus gallus)
Aves POLR1B 29 30
  • 71.44 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia POLR1B 30
  • 73 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia polr1b 29
  • 72.13 (n)
Str.17855 29
African clawed frog
(Xenopus laevis)
Amphibia MGC68946 29
Zebrafish
(Danio rerio)
Actinopterygii polr1b 29 30
  • 69.44 (n)
OneToOne
Rainbow Trout
(Oncorhynchus mykiss)
Actinopterygii Omy.6132 29
Fruit Fly
(Drosophila melanogaster)
Insecta RpI135 29 30
  • 52.24 (n)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP009539 29
  • 51.25 (n)
Worm
(Caenorhabditis elegans)
Secernentea F14B4.3 29
  • 52.82 (n)
rpoa-2 30
  • 43 (a)
OneToOne
K. Lactis Yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0B06303g 29
  • 52.63 (n)
A. gosspyii yeast
(Eremothecium gossypii)
Saccharomycetes AGOS_ABR029W 29
  • 52.48 (n)
Baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RPA135 29 32
  • 52.06 (n)
RPB2 30
  • 25 (a)
OneToMany
Thale Cress
(Arabidopsis thaliana)
eudicotyledons NRPA2 29
  • 51.07 (n)
Rice
(Oryza sativa)
Liliopsida Os.46652 29
Wheat
(Triticum aestivum)
Liliopsida Ta.4946 29
Fission Yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes rpa2 29
  • 53.91 (n)
Bread mold
(Neurospora crassa)
Ascomycetes NCU08616 29
  • 52.58 (n)
Sea Vase
(Ciona intestinalis)
Ascidiacea Cin.8215 29
Species where no ortholog for POLR1B was found in the sources mined by GeneCards:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)

Evolution for POLR1B Gene

ENSEMBL:
Gene Tree for POLR1B (if available)
TreeFam:
Gene Tree for POLR1B (if available)
Aminode:
Evolutionary constrained regions (ECRs) for POLR1B: view image
Alliance of Genome Resources:
Additional Orthologs for POLR1B

Paralogs for POLR1B Gene

Paralogs for POLR1B Gene

(2) SIMAP similar genes for POLR1B Gene using alignment to 15 proteins:

  • RPA2_HUMAN
  • C9JJG2_HUMAN
  • C9JS83_HUMAN
  • F5GZX4_HUMAN
  • F5H643_HUMAN
  • F8W898_HUMAN
  • F8WAK7_HUMAN
  • F8WBB9_HUMAN
  • F8WCS3_HUMAN
  • F8WDS4_HUMAN
  • H7C0D9_HUMAN
  • Q2TAM4_HUMAN
  • Q4QRK8_HUMAN
  • Q6DKI9_HUMAN
  • Q9BSR4_HUMAN
genes like me logo Genes that share paralogs with POLR1B: view

Variants for POLR1B Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for POLR1B Gene

SNP ID Clinical significance and condition Chr 02 pos Variation AA Info Type
932311 Pathogenic: Treacher Collins syndrome 4 112,568,874(+) T/A
NM_019014.6(POLR1B):c.2046T>A (p.Ser682Arg)
MISSENSE
932312 Pathogenic: Treacher Collins syndrome 4 112,575,328(+) C/T
NM_019014.6(POLR1B):c.3007C>T (p.Arg1003Cys)
MISSENSE
932313 Pathogenic: Treacher Collins syndrome 4 112,575,328(+) C/A
NM_019014.6(POLR1B):c.3007C>A (p.Arg1003Ser)
MISSENSE
rs1545133 -- p.Ser295Leu
VAR_071195 -- p.His887Arg

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for POLR1B Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for POLR1B Gene

Variant ID Type Subtype PubMed ID
esv3592009 CNV loss 21293372
nsv458997 CNV gain 19166990
nsv582708 CNV gain 21841781

Variation tolerance for POLR1B Gene

Residual Variation Intolerance Score: 10.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 11.26; 92.52% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for POLR1B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
POLR1B
Leiden Open Variation Database (LOVD)
POLR1B

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for POLR1B Gene

Disorders for POLR1B Gene

MalaCards: The human disease database

(1) MalaCards diseases for POLR1B Gene - From: OMI, CVR, and GCD

Disorder Aliases PubMed IDs
treacher collins syndrome 4
  • tcs4
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for POLR1B

genes like me logo Genes that share disorders with POLR1B: view

No data available for UniProtKB/Swiss-Prot and Genatlas for POLR1B Gene

Publications for POLR1B Gene

  1. POLR1B and neural crest cell anomalies in Treacher Collins syndrome type 4. (PMID: 31649276) Sanchez E … Geneviève D (Genetics in medicine : official journal of the American College of Medical Genetics 2020) 3 72
  2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier LW … Wilson RK (Nature 2005) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
  4. hRRN3 is essential in the SL1-mediated recruitment of RNA Polymerase I to rRNA gene promoters. (PMID: 11250903) Miller G … Zomerdijk JC (The EMBO journal 2001) 3 4
  5. ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents. (PMID: 32780723) Lan W … Iovanna J (JCI insight 2020) 3

Products for POLR1B Gene

Sources for POLR1B Gene