This gene encodes an RRM (RNA recognition motif)-containing protein that participates in the regulation of translation by recruiting ribosomal protein S6 kinase beta-1 to mRNAs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] See more...

Aliases for POLDIP3 Gene

Aliases for POLDIP3 Gene

  • DNA Polymerase Delta Interacting Protein 3 2 3 5
  • S6K1 Aly/REF-Like Target 2 3 4
  • Polymerase (DNA-Directed), Delta Interacting Protein 3 2 3
  • 46 KDa DNA Polymerase Delta Interaction Protein 3 4
  • Polymerase Delta-Interacting Protein 3 3 4
  • PDIP46 3 4
  • SKAR 3 4
  • Polymerase (DNA) Delta Interacting Protein 3 3
  • RNA-Binding Protein P46 3
  • KIAA1649 4
  • PDIP3 3
  • P46 4

External Ids for POLDIP3 Gene

Previous GeneCards Identifiers for POLDIP3 Gene

  • GC22M041211
  • GC22M041212
  • GC22M041304
  • GC22M042979
  • GC22M025940

Summaries for POLDIP3 Gene

Entrez Gene Summary for POLDIP3 Gene

  • This gene encodes an RRM (RNA recognition motif)-containing protein that participates in the regulation of translation by recruiting ribosomal protein S6 kinase beta-1 to mRNAs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

GeneCards Summary for POLDIP3 Gene

POLDIP3 (DNA Polymerase Delta Interacting Protein 3) is a Protein Coding gene. Among its related pathways are Gene Expression and Transport of Mature Transcript to Cytoplasm. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and nucleotide binding. An important paralog of this gene is ALYREF.

UniProtKB/Swiss-Prot Summary for POLDIP3 Gene

  • Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. Recruits activated ribosomal protein S6 kinase beta-1