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Aliases for POLA2 Gene
Aliases for POLA2 Gene
- DNA Polymerase Alpha 2, Accessory Subunit 2 3 5
- DNA Polymerase Alpha 70 KDa Subunit 2 3 4
- DNA Polymerase Alpha Subunit B 2 3 4
- Polymerase (DNA Directed), Alpha 2 (70kD Subunit) 2 3
- Polymerase (DNA) Alpha 2, Accessory Subunit 2 3
- Polymerase (DNA Directed), Alpha 2, Accessory Subunit 3
- Polymerase (DNA-Directed), Alpha (70kD) 3
- FLJ21662 2
- POLA2 5
External Ids for POLA2 Gene
- HGNC: 30073
- NCBI Entrez Gene: 23649
- Ensembl: ENSG00000014138
- UniProtKB/Swiss-Prot: Q14181
Previous GeneCards Identifiers for POLA2 Gene
- GC11P067545
- GC11P066711
- GC11P065279
- GC11P064804
- GC11P064786
- GC11P065029
- GC11P061356
Summaries for POLA2 Gene
GeneCards Summary for POLA2 Gene
POLA2 (DNA Polymerase Alpha 2, Accessory Subunit) is a Protein Coding gene. Among its related pathways are Telomere C-strand (Lagging Strand) Synthesis and Mitotic G1-G1/S phases. Gene Ontology (GO) annotations related to this gene include protein heterodimerization activity and DNA-directed DNA polymerase activity. An important paralog of this gene is ENSG00000285816.
UniProtKB/Swiss-Prot Summary for POLA2 Gene
-
Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis (PubMed:9705292). During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit POLA1, an accessory subunit POLA2 and two primase subunits, the catalytic subunit PRIM1 and the regulatory subunit PRIM2) is recruited to DNA at the replicative forks via direct interactions with MCM10 and WDHD1 (By similarity). The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands (By similarity). These primers are initially extended by the polymerase alpha catalytic subunit and subsequently transferred to polymerase delta and polymerase epsilon for processive synthesis on the lagging and leading strand, respectively (By similarity).
Additional gene information for POLA2 Gene
- HGNC (30073)
- NCBI Entrez Gene (23649)
- Ensembl (ENSG00000014138)
- UniProtKB/Swiss-Prot (Q14181)
- Open Targets Platform(ENSG00000014138)
- Search for POLA2 at DataMed
- Search for POLA2 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for POLA2 Gene
Genomics for POLA2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for POLA2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around POLA2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for POLA2
- Top Transcription factor binding sites by QIAGEN in the POLA2 gene promoter:
-
- AML1a
- c-Myc
- E47
- Max1
- Meis-1a
- Meis-1b
- MyoD
- NF-1
- NF-1/L
- SEF-1 (1)
Genomic Locations for POLA2 Gene
Latest Assembly
- chr11:65,261,917-65,306,269
- (GRCh38/hg38)
- Size:
- 44,353 bases
- Orientation:
- Plus strand
Previous Assembly
- chr11:65,029,433-65,066,156
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 36,724 bases
- Orientation:
- Plus strand
- chr11:65,029,233-65,073,060
- (GRCh37/hg19 by Ensembl)
- Size:
- 43,828 bases
- Orientation:
- Plus strand
Genomic View for POLA2 Gene
Genes around POLA2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q13.1 by HGNC
- 11q13.1 by Entrez Gene
- 11q13.1 by Ensembl
POLA2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for POLA2 Gene
Proteins for POLA2 Gene
-
Protein details for POLA2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q14181-DPOA2_HUMAN
- Recommended name:
- DNA polymerase alpha subunit B
- Protein Accession:
- Q14181
- B4DNB4
- Q9BPV3
Protein attributes for POLA2 Gene
- Size:
- 598 amino acids
- Molecular mass:
- 65948 Da
- Quaternary structure:
-
- Component of the alpha DNA polymerase complex (also known as the alpha DNA polymerase-primase complex) consisting of four subunits: the catalytic subunit POLA1, the regulatory subunit POLA2, and primase complex subunits PRIM1 and PRIM2 respectively (PubMed:9705292). Within the complex, POLA1 directly interacts with PRIM2/p58 (By similarity).
Three dimensional structures from OCA and Proteopedia for POLA2 Gene
Protein Expression for POLA2 Gene
Post-translational modifications for POLA2 Gene
- Phosphorylated in a cell cycle-dependent manner, in G2/M phase.
-
Ubiquitination at Lys72, Lys292, Lys160, Lys194, Lys207, Lys212, Lys500, and Lys564
- NX_Q14181 (NX_Q14181-1)
- Modification sites at PhosphoSitePlus
Other Protein References for POLA2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- G Biosciences Immunotag™ POLA2 Antibody
- Novus Biologicals Antibodies for POLA2
-
Abcam antibodies for POLA2
- Invitrogen Antibodies for POLA2 (AFLGC-POLA2)
-
Boster Bio Antibodies for POLA2
-
Custom Antibody ServicesProSci Antibodies for POLA2
-
Santa Cruz Biotechnology (SCBT) Antibodies for POLA2
Protein products for research
-
OriGene Purified Proteins for POLA2
- Search Origene for MassSpec and Protein Over-expression Lysates for POLA2
- Origene Custom Protein Services for POLA2
-
Abcam proteins for POLA2
No data available for DME Specific Peptides for POLA2 Gene
Domains & Families for POLA2 Gene
Gene Families for POLA2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for POLA2 Gene
- InterPro:
- Blocks:
-
- DNA polymerase alpha, subunit B N-terminal
- ProtoNet:
Suggested Antigen Peptide Sequences for POLA2 Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ60312, highly similar to DNA polymerase subunit alpha B (B4DNB4_HUMAN)
- DNA polymerase alpha 70 kDa subunit (DPOA2_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q14181UniProtKB/Swiss-Prot:
DPOA2_HUMAN :- The N-terminal 240 amino acids are sufficient to mediate complex formation.
- Belongs to the DNA polymerase alpha subunit B family.
- Domain:
-
- The N-terminal 240 amino acids are sufficient to mediate complex formation.
- Family:
-
- Belongs to the DNA polymerase alpha subunit B family.
Function for POLA2 Gene
Molecular function for POLA2 Gene
- UniProtKB/Swiss-Prot Function:
- Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis (PubMed:9705292). During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit POLA1, an accessory subunit POLA2 and two primase subunits, the catalytic subunit PRIM1 and the regulatory subunit PRIM2) is recruited to DNA at the replicative forks via direct interactions with MCM10 and WDHD1 (By similarity). The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands (By similarity). These primers are initially extended by the polymerase alpha catalytic subunit and subsequently transferred to polymerase delta and polymerase epsilon for processive synthesis on the lagging and leading strand, respectively (By similarity).
Phenotypes From GWAS Catalog for POLA2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003674 | molecular_function | ND | -- |
| GO:0003677 | DNA binding | IEA | -- |
| GO:0005515 | protein binding | IPI | 32814053 |
Phenotypes for POLA2 Gene
- MGI mutant phenotypes for POLA2:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for POLA2:
-
- Increased gamma-H2AX phosphorylation
- Mitotic spindle defects
- Increased vaccinia virus (VACV) infection
- no effect
- Decreased vaccinia virus (VACV) infection
- Decreased NF-kappaB reporter expression
- Resistant to vaccinia virus (VACV-A4L) infection
- Decreased viability after Maraba virus infection
- Decreased shRNA abundance (Z-score < -2)
- Increased shRNA abundance (Z-score > 2)
- Decreased viability with TRAIL
- Decreased viability in colon lineage; decreased viability in pancreas lineage
Animal Models for POLA2 Gene
- MGI Knock Outs for POLA2:
-
- Pola2 Pola2<tm1b(KOMP)Mbp>
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for POLA2 - Starting at $85 >
- * POLA2 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for POLA2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for POLA2
-
Santa Cruz Biotechnology (SCBT) CRISPR for POLA2
miRNA for POLA2 Gene
- miRTarBase miRNAs that target POLA2
-
- hsa-miR-1-3p (MIRT001348)
- hsa-miR-215-5p (MIRT024956)
- hsa-miR-192-5p (MIRT026640)
- mmu-miR-126a-5p (MIRT586294)
- mmu-miR-881-3p (MIRT586295)
- mmu-miR-674-5p (MIRT591089)
- mmu-miR-3473d (MIRT591090)
- hsa-miR-7977 (MIRT621034)
- hsa-miR-24-3p (MIRT621035)
- hsa-miR-4284 (MIRT621036)
- hsa-miR-383-3p (MIRT621037)
- hsa-miR-1265 (MIRT621038)
- hsa-miR-2392 (MIRT621039)
- hsa-miR-5684 (MIRT621040)
- hsa-miR-3149 (MIRT641481)
- hsa-miR-297 (MIRT641482)
- hsa-miR-675-3p (MIRT641483)
- hsa-miR-1185-2-3p (MIRT641484)
- hsa-miR-1185-1-3p (MIRT641485)
- hsa-let-7f-2-3p (MIRT641486)
- hsa-miR-4789-5p (MIRT641487)
- hsa-miR-98-3p (MIRT641488)
- hsa-let-7f-1-3p (MIRT641489)
- hsa-let-7b-3p (MIRT641490)
- hsa-let-7a-3p (MIRT641491)
- hsa-miR-145-3p (MIRT641492)
- hsa-miR-3171 (MIRT641493)
- hsa-miR-3605-5p (MIRT641494)
- hsa-miR-4729 (MIRT641495)
- hsa-miR-4666a-3p (MIRT641496)
- hsa-miR-381-3p (MIRT641497)
- hsa-miR-300 (MIRT641498)
- hsa-miR-6862-5p (MIRT649426)
- hsa-miR-4253 (MIRT649427)
- hsa-miR-3945 (MIRT649428)
- hsa-miR-3622b-5p (MIRT649429)
- hsa-miR-7703 (MIRT666882)
- hsa-miR-6720-5p (MIRT666883)
- hsa-miR-6512-3p (MIRT666884)
- hsa-miR-4252 (MIRT666885)
- hsa-miR-4793-3p (MIRT666886)
- hsa-miR-766-3p (MIRT666887)
- hsa-miR-1292-3p (MIRT666888)
- hsa-miR-6849-3p (MIRT666889)
- hsa-miR-1273g-3p (MIRT666890)
- hsa-miR-3940-3p (MIRT666891)
- hsa-miR-508-5p (MIRT666892)
- hsa-miR-4439 (MIRT666893)
- hsa-miR-3136-5p (MIRT666894)
- hsa-miR-5001-3p (MIRT666895)
- hsa-miR-6820-3p (MIRT666896)
- hsa-miR-3118 (MIRT666897)
- hsa-miR-134-5p (MIRT666898)
- hsa-miR-5581-5p (MIRT666899)
- hsa-miR-4297 (MIRT666900)
- hsa-miR-6857-3p (MIRT666901)
- hsa-miR-4513 (MIRT666902)
- hsa-miR-6855-3p (MIRT666903)
- hsa-miR-3117-5p (MIRT666904)
- hsa-miR-6730-3p (MIRT666905)
- hsa-miR-942-5p (MIRT666906)
- hsa-miR-199b-5p (MIRT666907)
- hsa-miR-199a-5p (MIRT666908)
- hsa-miR-4302 (MIRT666909)
- hsa-miR-888-3p (MIRT666910)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for POLA2
- Browse OriGene Inhibitory RNA Products For POLA2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for POLA2
Clone products for research
- Applied Biological Materials (abm): Clones for POLA2 - Starting at $45 >
- * POLA2 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
-
- MG205518
- MG209308
- MG218152
- MR205518
- MR205518L3
- MR205518L4
- MR209308
- MR209308L3
- MR209308L4
- MR218152
- MR218152L3
- MR218152L4
- RC201145
- RC201145L3
- RC201145L4
- RG201145
- RR208936
- RR208936L3
- RR208936L4
- MR205518L3V
- MR205518L4V
- MR209308L3V
- MR209308L4V
- MR218152L3V
- MR218152L4V
- RC201145L3V
- RC201145L4V
- RR208936L3V
- RR208936L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for POLA2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for POLA2
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for POLA2 Gene
Localization for POLA2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for POLA2 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 4 |
| cytoskeleton | 2 |
| extracellular | 1 |
| mitochondrion | 1 |
- Nucleoplasm (3)
- Cytosol (1)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005658 | alpha DNA polymerase:primase complex | IBA,IDA | 8026492 |
| GO:0005829 | cytosol | IDA | -- |
Pathways & Interactions for POLA2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Telomere C-strand (Lagging Strand) Synthesis |
.67
Cell cycle Transition and termination of DNA replication
.48
|
|
| 2 | E2F mediated regulation of DNA replication |
.64
Cell cycle Start of DNA replication in early S phase
.53
|
|
| 3 | CDK-mediated phosphorylation and removal of Cdc6 |
.93
.93
|
.80
.78
|
| 4 | Mitotic G1-G1/S phases |
.83
|
|
| 5 | Cell Cycle, Mitotic |
.83
|
|
Pathways by source for POLA2 Gene
2 BioSystems pathways for POLA2 Gene
25 Reactome pathways for POLA2 Gene
1 KEGG pathway for POLA2 Gene
3 GeneGo (Thomson Reuters) pathways for POLA2 Gene
- Cell cycle Start of DNA replication in early S phase
- Cell cycle Transition and termination of DNA replication
- Transcription Ligand-dependent activation of the ESR1/SP pathway
Interacting Proteins for POLA2 Gene
Selected Interacting proteins:
Q14181-DPOA2_HUMAN
ENSP00000265465
for POLA2 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for POLA2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000082 | G1/S transition of mitotic cell cycle | TAS | -- |
| GO:0006260 | DNA replication | IEA,NAS | 8223465 |
| GO:0006269 | DNA replication, synthesis of RNA primer | IDA | 8026492 |
| GO:0006270 | DNA replication initiation | TAS | -- |
| GO:0032201 | telomere maintenance via semi-conservative replication | TAS | -- |
No data available for SIGNOR curated interactions for POLA2 Gene
Drugs & Compounds for POLA2 Gene
(1) ApexBio Compounds for POLA2 Gene
| Compound | Action | Cas Number |
|---|---|---|
| Fludarabine Phosphate (Fludara) | Inhibits STAT1 activation and DNA synthesis | 75607-67-9 |
Transcripts for POLA2 Gene
mRNA/cDNA for POLA2 Gene
- 1 REFSEQ mRNAs :
- 12 NCBI additional mRNA sequence :
- 8 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000265465 3544 nts (view in UCSC)
- ENST00000525924 873 nts (view in UCSC)
- ENST00000527618 1924 nts (view in UCSC)
- ENST00000527850 2403 nts (view in UCSC)
- ENST00000532391 580 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for POLA2 - Starting at $85 >
- * POLA2 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for POLA2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for POLA2
-
Santa Cruz Biotechnology (SCBT) CRISPR for POLA2
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for POLA2
- Browse OriGene Inhibitory RNA Products For POLA2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for POLA2
Clone products for research
- Applied Biological Materials (abm): Clones for POLA2 - Starting at $45 >
- * POLA2 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
-
- MG205518
- MG209308
- MG218152
- MR205518
- MR205518L3
- MR205518L4
- MR209308
- MR209308L3
- MR209308L4
- MR218152
- MR218152L3
- MR218152L4
- RC201145
- RC201145L3
- RC201145L4
- RG201145
- RR208936
- RR208936L3
- RR208936L4
- MR205518L3V
- MR205518L4V
- MR209308L3V
- MR209308L4V
- MR218152L3V
- MR218152L4V
- RC201145L3V
- RC201145L4V
- RR208936L3V
- RR208936L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for POLA2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for POLA2
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | ^ | 15a | · | 15b | ^ | 16 | ^ | 17a | · | 17b | · | 17c | ^ | 18a | · |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - |
| ExUns: | 18b |
|---|---|
| SP1: | |
| SP2: | |
| SP3: | |
| SP4: | |
| SP5: | |
| SP6: | |
| SP7: |
Relevant External Links for POLA2 Gene
- GeneLoc Exon Structure for
- POLA2
Expression for POLA2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Neural Tube (Nervous System)
- Brain (Nervous System)
- Gut Tube (Gastrointestinal Tract)
- Kidney (Urinary System)
This gene is overexpressed in Pancreas (30.5), Heart (18.9), and Fetal ovary (8.5).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for POLA2 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for POLA2
SOURCE GeneReport for Unigene cluster for POLA2 Gene:
Hs.201897Evidence on tissue expression from TISSUES for POLA2 Gene
- Lung(4.5)
- Heart(4.1)
- Nervous system(3.9)
Primer products for research
-
OriGene qPCR primer pairs for POLA2
-
OriGene qPCR primer pairs and template standards for POLA2
Gene Expression Assays for research
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for POLA2 Gene
Orthologs for POLA2 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | POLA2 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | POLA2 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | POLA2 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Pola2 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Pola2 30 17 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
| -- 31 |
|
OneToMany | |||
| -- 31 |
|
OneToMany | |||
| Oppossum (Monodelphis domestica) |
Mammalia | POLA2 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | LOC100859759 30 |
|
||
| POLA2 31 |
|
OneToOne | |||
| Lizard (Anolis carolinensis) |
Reptilia | POLA2 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | pola2 30 |
|
||
| Str.6808 30 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.4593 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | pola2 30 31 |
|
OneToOne | |
| wufb48f05 30 |
|
||||
| Fruit Fly (Drosophila melanogaster) |
Insecta | DNApol-alpha73 30 31 |
|
OneToOne | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP004392 30 |
|
||
| Worm (Caenorhabditis elegans) |
Secernentea | div-1 31 |
|
OneToOne | |
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | POL12 31 33 |
|
OneToOne | |
| Thale Cress (Arabidopsis thaliana) |
eudicotyledons | POLA2 30 |
|
||
| Rice (Oryza sativa) |
Liliopsida | Os12g0242900 30 |
|
- Species where no ortholog for POLA2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)