Aliases for PNMA3 Gene
External Ids for PNMA3 Gene
Previous GeneCards Identifiers for PNMA3 Gene
The protein encoded by this gene belongs to the paraneoplastic antigen MA (PNMA) family, which shares homology with retroviral Gag proteins. The PNMA antigens are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
GeneCards Summary for PNMA3 Gene
PNMA3 (PNMA Family Member 3) is a Protein Coding gene. Diseases associated with PNMA3 include Cd3zeta Deficiency and Tracheitis. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is PNMA5.