Aliases for PNCK Gene
External Ids for PNCK Gene
Previous GeneCards Identifiers for PNCK Gene
PNCK is a member of the calcium/calmodulin-dependent protein kinase family of protein serine/threonine kinases (see CAMK1; MIM 604998) (Gardner et al., 2000 [PubMed 10673339]).[supplied by OMIM, Mar 2008]
GeneCards Summary for PNCK Gene
PNCK (Pregnancy Up-Regulated Nonubiquitous CaM Kinase) is a Protein Coding gene. Diseases associated with PNCK include Megalencephalic Leukoencephalopathy With Subcortical Cysts 1. Among its related pathways are B Cell Receptor Signaling Pathway (sino) and VEGF Signaling. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is CAMK1.
UniProtKB/Swiss-Prot Summary for PNCK Gene
Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates CREB1 and SYN1/synapsin I. Phosphorylates and activates CAMK1 (By similarity).