Aliases for PM20D1 Gene
External Ids for PM20D1 Gene
Previous GeneCards Identifiers for PM20D1 Gene
GeneCards Summary for PM20D1 Gene
PM20D1 (Peptidase M20 Domain Containing 1) is a Protein Coding gene. Diseases associated with PM20D1 include Chlamydia Pneumonia. Gene Ontology (GO) annotations related to this gene include hydrolase activity and peptidase activity. An important paralog of this gene is CNDP2.
UniProtKB/Swiss-Prot Summary for PM20D1 Gene
Bidirectional N-fatty-acyl amino acid synthase/hydrolase that regulates the production of N-fatty-acyl amino acids. These metabolites are endogenous chemical uncouplers of mitochondrial respiration. In an UCP1-independent manner, maybe through interaction with mitochondrial transporters, they promote proton leakage into the mitochondrial matrix. Thereby, this secreted protein may indirectly regulate the bodily dissipation of chemical energy as heat through thermogenic respiration.