Aliases for PLXNB1 Gene
External Ids for PLXNB1 Gene
Previous HGNC Symbols for PLXNB1 Gene
Previous GeneCards Identifiers for PLXNB1 Gene
GeneCards Summary for PLXNB1 Gene
PLXNB1 (Plexin B1) is a Protein Coding gene. Diseases associated with PLXNB1 include Breast Cancer and Walker-Warburg Syndrome. Among its related pathways are Signaling by GPCR and Development Slit-Robo signaling. Gene Ontology (GO) annotations related to this gene include GTPase activating protein binding. An important paralog of this gene is PLXNB3.
UniProtKB/Swiss-Prot Summary for PLXNB1 Gene
Receptor for SEMA4D (PubMed:19843518, PubMed:20877282, PubMed:21912513). Plays a role in GABAergic synapse development (By similarity). Mediates SEMA4A- and SEMA4D-dependent inhibitory synapse development (By similarity). Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton (PubMed:12196628, PubMed:15210733). Plays a role in axon guidance, invasive growth and cell migration (PubMed:12198496).