Aliases for PLVAP Gene
External Ids for PLVAP Gene
Previous GeneCards Identifiers for PLVAP Gene
GeneCards Summary for PLVAP Gene
PLVAP (Plasmalemma Vesicle Associated Protein) is a Protein Coding gene. Diseases associated with PLVAP include Diarrhea 10, Protein-Losing Enteropathy Type and Congenital Diarrhea 7 With Exudative Enteropathy. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity.
UniProtKB/Swiss-Prot Summary for PLVAP Gene
Endothelial cell-specific membrane protein involved in the formation of the diaphragms that bridge endothelial fenestrae. It is also required for the formation of stomata of caveolae and transendothelial channels. Functions in microvascular permeability, endothelial fenestrae contributing to the passage of water and solutes and regulating transcellular versus paracellular flow in different organs. Plays a specific role in embryonic development.