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PLPPR2 (Phospholipid Phosphatase Related 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. An important paralog of this gene is PLPPR5.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IPI | 32296183 |
GO:0008195 | phosphatidate phosphatase activity | IBA | 21873635 |
GO:0016787 | hydrolase activity | IEA | -- |
GO:0042577 | lipid phosphatase activity | IBA | 21873635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005887 | integral component of plasma membrane | IBA | 21873635 |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Peptide ligand-binding receptors | ||
2 | Signaling by GPCR | ||
3 | Lysosphingolipid and LPA receptors | ||
4 | triacylglycerol biosynthesis |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006644 | phospholipid metabolic process | IBA | 21873635 |
GO:0007165 | signal transduction | IBA | 21873635 |
GO:0016311 | dephosphorylation | IEA | -- |
GO:0046839 | phospholipid dephosphorylation | IBA | 21873635 |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Cow (Bos Taurus) |
Mammalia | -- 31 |
|
OneToOne | |
LPPR2 30 |
|
||||
Dog (Canis familiaris) |
Mammalia | LPPR2 30 |
|
||
-- 31 |
|
OneToOne | |||
Mouse (Mus musculus) |
Mammalia | BC018242 30 31 |
|
OneToOne | |
Plppr2 17 |
|
||||
Rat (Rattus norvegicus) |
Mammalia | Lppr2 30 |
|
||
Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | LOC100485784 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | LOC571463 30 |
|
||
lppr2a 31 |
|
OneToMany | |||
CABZ01025393.1 31 |
|
OneToMany | |||
-- 30 |
|
SNP ID | Clinical significance and condition | Chr 19 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
VAR_038546 | A colorectal cancer sample |
p.Thr155Met |
No disorders were found for PLPPR2 Gene.