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PLET1 (Placenta Expressed Transcript 1) is a Protein Coding gene. Diseases associated with PLET1 include Sebaceous Gland Neoplasm and Sebaceous Adenoma. Among its related pathways are Metabolism of proteins and Post-translational modification- synthesis of GPI-anchored proteins.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005576 | extracellular region | TAS | -- |
GO:0005886 | plasma membrane | TAS | -- |
GO:0009897 | external side of plasma membrane | IBA | 21873635 |
GO:0016020 | membrane | IEA | -- |
GO:0016324 | apical plasma membrane | IBA,ISS | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0001953 | negative regulation of cell-matrix adhesion | IBA,ISS | -- |
GO:0030154 | cell differentiation | IEA | -- |
GO:0030335 | positive regulation of cell migration | IBA,ISS | -- |
GO:0035313 | wound healing, spreading of epidermal cells | IBA,ISS | -- |
This gene was present in the common ancestor of mammals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | C11H11orf34 30 |
|
||
PLET1 31 |
|
OneToOne | |||
Dog (Canis familiaris) |
Mammalia | C5H11orf34 30 |
|
||
PLET1 31 |
|
OneToOne | |||
Cow (Bos Taurus) |
Mammalia | C15H11orf34 30 |
|
||
PLET1 31 |
|
OneToOne | |||
Rat (Rattus norvegicus) |
Mammalia | Plet1 30 |
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||
Mouse (Mus musculus) |
Mammalia | Plet1 30 17 |
|
||
1600029D21Rik 31 |
|
OneToOne | |||
Oppossum (Monodelphis domestica) |
Mammalia | PLET1 31 |
|
OneToOne |
SNP ID | Clinical significance and condition | Chr 11 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs2564872 | - |
p.Ser142Pro |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv148e201 | CNV | deletion | 23290073 |
dgv706e59 | CNV | duplication | 20981092 |
esv2661060 | CNV | deletion | 23128226 |
esv2677815 | CNV | deletion | 23128226 |
esv2745078 | CNV | deletion | 23290073 |
esv3415331 | CNV | duplication | 20981092 |
nsv1138075 | CNV | deletion | 24896259 |
Disorder | Aliases | PubMed IDs |
---|---|---|
sebaceous gland neoplasm |
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|
sebaceous adenoma |
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|
hyaline fibromatosis syndrome |
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|