Aliases for PLEKHG4 Gene
Aliases for PLEKHG4 Gene
External Ids for PLEKHG4 Gene
- HGNC: 24501
- Entrez Gene: 25894
- Ensembl: ENSG00000196155
- OMIM: 609526
- UniProtKB: Q58EX7
Previous HGNC Symbols for PLEKHG4 Gene
- SCA4
Previous GeneCards Identifiers for PLEKHG4 Gene
- GC16P065870
- GC16P053184
Summaries for PLEKHG4 Gene
-
The protein encoded by this gene can function as a guanine nucleotide exchange factor (GEF) and may play a role in intracellular signaling and cytoskeleton dynamics at the Golgi apparatus. Polymorphisms in the region of this gene have been found to be associated with spinocerebellar ataxia in some study populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
GeneCards Summary for PLEKHG4 Gene
PLEKHG4 (Pleckstrin Homology And RhoGEF Domain Containing G4) is a Protein Coding gene. Diseases associated with PLEKHG4 include Spinocerebellar Ataxia 4 and Indian Tick Typhus. Gene Ontology (GO) annotations related to this gene include Rho guanyl-nucleotide exchange factor activity. An important paralog of this gene is PLEKHG4B.
UniProtKB/Swiss-Prot for PLEKHG4 Gene
-
Possible role in intracellular signaling and cytoskeleton dynamics at the Golgi.
Additional gene information for PLEKHG4 Gene
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PLEKHG4 Gene
Genomics for PLEKHG4 Gene
GeneHancer (GH) Regulatory Elements for PLEKHG4 Gene
Promoters and enhancers for PLEKHG4 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around PLEKHG4 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the PLEKHG4 gene promoter:
Regulatory Element Products
Genomic Locations for PLEKHG4 Gene
Genomic Locations for PLEKHG4 Gene
- chr16:67,277,510-67,289,500
- (GRCh38/hg38)
- Size:
- 11,991 bases
- Orientation:
- Plus strand
- chr16:67,311,413-67,323,403
- (GRCh37/hg19)
Genomic View for PLEKHG4 Gene
Genes around PLEKHG4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 16q22.1 by Ensembl
- 16q22.1 by Entrez Gene
- 16q22.1 by HGNC
PLEKHG4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for PLEKHG4 Gene
Proteins for PLEKHG4 Gene
-
Protein details for PLEKHG4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q58EX7-PKHG4_HUMAN
- Recommended name:
- Puratrophin-1
- Protein Accession:
- Q58EX7
- Q4G0J8
- Q4H485
- Q56A69
- Q9H7K4
- Q9UFW0
Protein attributes for PLEKHG4 Gene
- Size:
- 1191 amino acids
- Molecular mass:
- 130803 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAH82974.1; Type=Frameshift; Positions=3; Evidence={ECO:0000305}; Sequence=BAB15765.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for PLEKHG4 Gene
Post-translational modifications for PLEKHG4 Gene
- Ubiquitination at isoforms=2405, Lys423, Lys511, Lys608, Lys674, isoforms=2869, isoforms=2922, and isoforms=21049
Other Protein References for PLEKHG4 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for PLEKHG4
-
Abcam antibodies for PLEKHG4
- Invitrogen Antibodies for PLEKHG4
- GeneTex PLEKHG4 antibody for PLEKHG4
Protein Products
-
OriGene Purified Proteins for PLEKHG4
- Search Origene for MassSpec and Protein Over-expression Lysates for PLEKHG4
- Origene Custom Protein Services for PLEKHG4
- Search GeneTex for Proteins for PLEKHG4
-
Abcam proteins for PLEKHG4
Assay Products
No data available for DME Specific Peptides for PLEKHG4 Gene
Domains & Families for PLEKHG4 Gene
Gene Families for PLEKHG4 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for PLEKHG4 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for PLEKHG4 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for PLEKHG4 Gene
Function for PLEKHG4 Gene
Molecular function for PLEKHG4 Gene
- UniProtKB/Swiss-Prot Function:
- Possible role in intracellular signaling and cytoskeleton dynamics at the Golgi.
Phenotypes From GWAS Catalog for PLEKHG4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005089 | Rho guanyl-nucleotide exchange factor activity | IEA | -- |
| GO:0005515 | protein binding | IPI | 25416956 |
Phenotypes for PLEKHG4 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for PLEKHG4
-
-
ViGene Biosciences lentiviral particle packaged cDNA for PLEKHG4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for PLEKHG4 gene
- Search ViGene Biosciences for PLEKHG4
CRISPR Products
-
OriGene CRISPR knockouts for PLEKHG4
- genomics-online: gRNA clones - Search results for available PLEKHG4 gene related products
- Applied Biological Materials CRISPR for PLEKHG4
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for PLEKHG4
- GenScript: Design CRISPR guide RNA sequences for PLEKHG4
miRNA for PLEKHG4 Gene
- miRTarBase miRNAs that target PLEKHG4
-
- hsa-mir-335-5p (MIRT018367)
- hsa-mir-124-3p (MIRT022840)
- hsa-mir-93-3p (MIRT038911)
- hsa-mir-331-3p (MIRT043462)
- hsa-mir-632 (MIRT712868)
- hsa-mir-4288 (MIRT712869)
- hsa-mir-6828-3p (MIRT712870)
- hsa-mir-346 (MIRT712871)
- hsa-mir-4261 (MIRT712872)
- hsa-mir-6502-5p (MIRT712873)
- hsa-mir-1301-5p (MIRT712874)
- hsa-mir-767-3p (MIRT712875)
- hsa-mir-654-3p (MIRT712876)
- hsa-mir-3688-3p (MIRT712877)
miRNA Products
- Search ViGene Biosciences for PLEKHG4
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for PLEKHG4
- Browse OriGene Inhibitory RNA Products For PLEKHG4
- genomics-online: shRNA clones - Search results for available PLEKHG4 gene related products
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ViGene Biosciences ready-to-package AAV shRNAs for PLEKHG4 gene
Clone Products
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OriGene ORF clones in human for PLEKHG4
- RG209583
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- RC209583L1
- RC209583
- RG226331
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- RC209583L2V
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- RC226354L2V
- RC226354L1V
- RC226353L2V
- RC226353L1V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- VectorBuilder custom plasmid, inducible vectors for PLEKHG4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PLEKHG4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available PLEKHG4 gene related products
- orf clones - Search results for available PLEKHG4 gene related products
- Applied Biological Materials Clones for PLEKHG4
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for PLEKHG4
-
ViGene Biosciences adenoviral particle packaged cDNA for PLEKHG4 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for PLEKHG4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for PLEKHG4 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for PLEKHG4 Gene
Localization for PLEKHG4 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 4 |
| cytosol | 4 |
- Cell Junctions (2)
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for PLEKHG4 Gene
Pathways & Interactions for PLEKHG4 Gene
No Data Available
Interacting Proteins for PLEKHG4 Gene
Selected Interacting proteins:
Q58EX7-PKHG4_HUMAN
ENSP00000353646
for PLEKHG4 Gene via
IID
UniProtKB
STRING
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0035023 | regulation of Rho protein signal transduction | IEA | -- |
| GO:0090630 | activation of GTPase activity | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for PLEKHG4 Gene
Transcripts for PLEKHG4 Gene
mRNA/cDNA for PLEKHG4 Gene
- (9) REFSEQ mRNAs :
- (11) Additional mRNA sequences :
- (94) Selected AceView cDNA sequences:
- (15) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for PLEKHG4 Gene
CRISPR Products
-
OriGene CRISPR knockouts for PLEKHG4
- genomics-online: gRNA clones - Search results for available PLEKHG4 gene related products
- Applied Biological Materials CRISPR for PLEKHG4
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for PLEKHG4
- GenScript: Design CRISPR guide RNA sequences for PLEKHG4
miRNA Products
- Search ViGene Biosciences for PLEKHG4
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for PLEKHG4
- Browse OriGene Inhibitory RNA Products For PLEKHG4
- genomics-online: shRNA clones - Search results for available PLEKHG4 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for PLEKHG4 gene
Clone Products
-
OriGene ORF clones in human for PLEKHG4
- RG209583
- RC209583L2
- RC209583L1
- RC209583
- RG226331
- RC226331L2
- RC226331L1
- RC226331
- RG226355
- RC226355L2
- RC226355L1
- RC226355
- RG226354
- RC226354L2
- RC226354L1
- RC226354
- RG226353
- RC226353L2
- RC226353L1
- RC226353
- RC209583L2V
- RC209583L1V
- RC226331L2V
- RC226331L1V
- RC226355L2V
- RC226355L1V
- RC226354L2V
- RC226354L1V
- RC226353L2V
- RC226353L1V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for PLEKHG4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PLEKHG4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available PLEKHG4 gene related products
- orf clones - Search results for available PLEKHG4 gene related products
- Applied Biological Materials Clones for PLEKHG4
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9a | · | 9b | ^ | 10a | · | 10b | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
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| SP5: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||
| SP7: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | - | - |
| ExUns: | 22 | ^ | 23 | ^ | 24a | · | 24b | ^ | 25a | · | 25b | ^ | 26a | · | 26b | ^ | 27a | · | 27b | · | 27c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||
| SP4: | - | ||||||||||||||||||||
| SP5: | - | ||||||||||||||||||||
| SP6: | - | - | - | - | - | - | |||||||||||||||
| SP7: | |||||||||||||||||||||
| SP8: | |||||||||||||||||||||
| SP9: |
Expression for PLEKHG4 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Ovary (Reproductive System)
- Cumulus Cells Antral Follicle
- Granulosa Cells Primary Follicle
-
Testis (Reproductive System)
mRNA differential expression in normal tissues according to GTEx for PLEKHG4 Gene
This gene is overexpressed in Testis (x8.7).
This gene is overexpressed in Plasma (37.2), Ovary (16.4), and Testis (14.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for PLEKHG4 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of PLEKHG4 Gene:
PLEKHG4SOURCE GeneReport for Unigene cluster for PLEKHG4 Gene:
Hs.188781mRNA Expression by UniProt/SwissProt for PLEKHG4 Gene:
Q58EX7-PKHG4_HUMAN
Tissue specificity:
Expressed in kidney, Leydig cells in the testis, epithelial cells in the prostate gland and Langerhans islet in the pancreas. Isoform 1 and isoform 3 are strongly expressed in Purkinje cells and to a lower extent in other neurons (at protein level). Widely expressed at low levels. More strongly expressed in testis and pancreas.
Evidence on tissue expression from TISSUES for PLEKHG4 Gene
- Nervous system(4.3)
- Skin(4.2)
- Spleen(4.2)
- Eye(4.1)
Phenotype-based relationships between genes and organs from Gene ORGANizer for PLEKHG4 Gene
Germ Layers:
- ectoderm
- mesoderm
Systems:
- nervous
- skeletal muscle
- skeleton
Regions:
Head and neck:
- brain
- cerebellum
- cranial nerve
- eye
- head
Limb:
- foot
- lower limb
- upper limb
General:
- peripheral nerve
- peripheral nervous system
- spinal cord
Primer Products
-
OriGene qPCR primer pairs for PLEKHG4
- genomics-online: primer clones - Search results for available PLEKHG4 gene related products
Orthologs for PLEKHG4 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | PLEKHG4 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | PLEKHG4 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | PLEKHG4 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Plekhg4 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Plekhg4 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | PLEKHG4 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | PLEKHG4 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | PLEKHG4 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | PLEKHG4 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | plekhg4 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | plekhg4 33 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG30456 34 |
|
ManyToMany | |
| CG33275 34 |
|
ManyToMany | |||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany | |
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.8422 33 |
|
- Species where no ortholog for PLEKHG4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for PLEKHG4 Gene
Paralogs for PLEKHG4 Gene
(2) SIMAP similar genes for PLEKHG4 Gene using alignment to 10 proteins:
Variants for PLEKHG4 Gene
| SNP ID | Clin | Chr 16 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs886041026 | uncertain-significance, Spinocerebellar ataxia 31 | 67,280,029(+) | C/G/T | 5_prime_UTR_variant, non_coding_transcript_variant | |
| rs11860295 | likely-benign, not specified | 67,282,331(+) | C/T | coding_sequence_variant, missense_variant, non_coding_transcript_variant | |
| rs3868142 | likely-benign, not specified | 67,286,320(+) | G/A | coding_sequence_variant, missense_variant, non_coding_transcript_variant | |
| rs8044843 | likely-benign, not specified | 67,284,339(+) | A/G/T | coding_sequence_variant, missense_variant, non_coding_transcript_variant | |
| rs1000129864 | -- | 67,289,884(+) | C/T | downstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv827708 | CNV | gain | 20364138 |
| nsv827707 | CNV | loss | 20364138 |
| nsv572906 | CNV | loss | 21841781 |
| nsv572905 | CNV | loss | 21841781 |
| nsv524492 | CNV | loss | 19592680 |
| nsv524363 | CNV | loss | 19592680 |
| nsv522852 | CNV | gain | 19592680 |
| nsv471092 | CNV | gain | 18288195 |
| nsv457513 | CNV | loss | 19166990 |
| nsv1144771 | CNV | deletion | 24896259 |
Residual Variation Intolerance Score:
80.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
16.61;
97.82% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for PLEKHG4 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PLEKHG4 Gene
Disorders for PLEKHG4 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| spinocerebellar ataxia 4 |
|
|
| indian tick typhus |
|
|
| queensland tick typhus |
|
|
| israeli tick typhus |
|
|
| flinders island spotted fever |
|
|
Search PLEKHG4 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for PLEKHG4
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for PLEKHG4 Gene
Publications for PLEKHG4 Gene
- Mutations of the puratrophin-1 (PLEKHG4) gene on chromosome 16q22.1 are not a common genetic cause of cerebellar ataxia in a European population. (PMID: 16491300) Wieczorek S … Epplen JT (Journal of human genetics 2006) 2 3 22 44 58
- An autosomal dominant cerebellar ataxia linked to chromosome 16q22.1 is associated with a single-nucleotide substitution in the 5' untranslated region of the gene encoding a protein with spectrin repeat and Rho guanine-nucleotide exchange-factor domains. (PMID: 16001362) Ishikawa K … Mizusawa H (American journal of human genetics 2005) 2 3 4 22 58
- [Study on the single-nucleotide substitution (c.-16C to T) of the PURATROPHIN-1 gene in Chinese patients with spinocerebellar ataxia]. (PMID: 19065522) Zhou Y … Tang B (Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 2008) 3 44 58
- Redefining the disease locus of 16q22.1-linked autosomal dominant cerebellar ataxia. (PMID: 17611710) Amino T … Mizusawa H (Journal of human genetics 2007) 3 4 58
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
Products for PLEKHG4 Gene
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- Browse R&D Systems for biochemical assays
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- Custom Antibody Services
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- OriGene Purified Proteins for PLEKHG4
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- Origene shrna, sirna, and RNAi products in human, mouse, rat for PLEKHG4
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- OriGene qPCR primer pairs for PLEKHG4
- OriGene CRISPR knockouts for PLEKHG4
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- RC226353L1V
- RC226353L2V
- RC226354L1V
- RC226354L2V
- RC226355L1V
- RC226355L2V
- RC226331L1V
- RC226331L2V
- RC209583L1V
- RC209583L2V
- RC226353
- RC226353L1
- RC226353L2
- RG226353
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Sources for PLEKHG4 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew